Results 21 to 30 of about 7,295,578 (250)
Drug-drug interactions in the hospital [PDF]
, 2007 Introduction Drug interaction screening programs are an important tool to check prescriptions of multiple drugs for potential drug-drug interactions (pDDIs). Several programs are available on the market.
Vonbach, Priska
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Protein-Ligand Interactions and Drug Design
, 2021 This detailed book collects modern and established computer-based methods aimed at addressing the drug discovery challenge from disparate perspectives by exploiting information on ligand-protein recognition.
Ballante, Flavio,
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INNOVATIONS in Pharmacy, 2022 Background: Pharmacogenomics (PGx) can provide more precision in determining causation of adverse drug reactions (ADRs) from drug-drug-gene interaction clinical application.
Jade Nanan +2 more
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Drug-Drug-Gene Interactions: A Call for Clinical Consideration [PDF]
, 2021 It is widely accepted that both comedications and genetic factors may contribute to variation of drug response. Clinical decision support systems increasingly consider recommendations on drug– drug interactions (DDIs) during electronic prescribing, and ...
Cascorbi, Ingolf +3 more
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Potential drug interactions : exposure and management in hospital and ambulatory settings [PDF]
, 2006 Health care professionals are responsible to ensure safe dispensing and use of drug regimens involving the use of drug combinations that may interact and cause serious adverse events.
Indermitte, Jörg Lorenz
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Drug–Drug–Gene Interactions in Cardiovascular Medicine
Pharmacogenomics and Personalized Medicine, 2022 Innocent G Asiimwe, Munir Pirmohamed The Wolfson Centre for Personalized Medicine, MRC Centre for Drug Safety Science, Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool ...
Asiimwe IG, Pirmohamed M
doaj
The evolution of drug-activated nuclear receptors: one ancestral gene diverged into two xenosensor genes in mammals [PDF]
, 2004 BACKGROUND: Drugs and other xenobiotics alter gene expression of cytochromes P450 (CYP) by activating the pregnane X receptor (PXR) and constitutive androstane receptor (CAR) in mammals.
Urs A Meyer +26 more
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Prediction of human drug clearance and anticipation of clinical drug-drug interaction potential from in vitro drug transport studies [PDF]
, 2014 A major concern in drug development is the characterization of new molecular entities (NMEs) with respect to their safety and efficacy. Both factors are determined by the drug’s exposure within the body which itself is affected by drug clearance ...
Kunze, Annett
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Expression of drug transporters in intestine and blood [PDF]
, 2005 Proteins that are capable to transport molecules across membranes are fundamental for the accurate functioning of the body. Many diseases have their cause in a dysfunction of a particular transport protein.
Zimmermann, Christian
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PLoS ONE, 2022 In recent years, drug sensitivity prediction has garnered a great deal of attention due to the growing interest in precision medicine. Several computational methods have been developed for drug sensitivity prediction and the identification of related ...
Heewon Park +3 more
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