Results 31 to 40 of about 7,295,578 (250)
Learning Petri net models of non-linear gene interactions [PDF]
, 2005 Understanding how an individual's genetic make-up influences their risk of disease is a problem of paramount importance. Although machine-learning techniques are able to uncover the relationships between genotype and disease, the problem of automatically
Mayo, Michael
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Cancer Informatics, 2018 Understanding gene-gene interaction and its causal relationship to protein-protein interaction is a viable route for understanding drug action at the genetic level, which is largely hindered by inability to robustly map gene regulatory networks. Here, we
Adel Aloraini, Karim M ElSawy
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Pharmacological approach to Drug and Drug-Food Interactions
, 2023 Medication interactions must be taken into consideration in order to avoid toxicities, side effects, and lower efficacy brought on by subtherapeutic drug doses.
Hasan, Fatima
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A novel approach to simulate gene-environment interactions in complex diseases [PDF]
, 2010 Background: Complex diseases are multifactorial traits caused by both genetic and environmental factors. They represent the major part of human diseases and include those with largest prevalence and mortality (cancer, heart disease, obesity, etc ...
Amato, Roberto +25 more
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BMC Bioinformatics, 2023 This paper applies different link prediction methods on a knowledge graph generated from biomedical literature, with the aim to compare their ability to identify unknown drug-gene interactions and explain their predictions.
Fotis Aisopos, Georgios Paliouras
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Prediction of drug-drug interactions from chemogenomic and gene-gene interactions and analysis of drug-drug interactions [PDF]
, 2013 The interactions between multiple drugs administered to an organism concurrently, whether in the form of synergy or antagonism, are of clinical relevance.
Akhmetov, Azat
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Pharmacogenomic network analysis of the gene-drug interaction landscape underlying drug disposition
Computational and Structural Biotechnology Journal, 2020 In recent decades the identification of pharmacogenomic gene-drug associations has evolved tremendously. Despite this progress, a major fraction of the heritable inter-individual variability remains elusive.
Yitian Zhou, Volker M. Lauschke
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Frontiers in Genetics, 2014 New approaches to toxicity testing have incorporated high-throughput screening across a broad-range of in vitro assays to identify potential key events in response to chemical or drug treatment.
Oscar Takeo Suzuki +12 more
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Drug interactions and hepatotoxicity of clopidogrel [PDF]
, 2010 Clopidogrel (Plavix¨) is an antiplatelet drug, which is clinically used in combination with aspirin to reduce cardiovascular events in patients undergoing percutaneous coronary intervention or in patients suffering from acute coronary syndromes ...
Zahno, Anja-Christina
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