Results 31 to 40 of about 7,761,768 (249)
Discovering Drug-Drug Interactions Using Association Rule Mining from Electronic Health Records [PDF]
, 2023 In this paper, we propose utilising Electronic Health Records (EHR) to discover previously unknown drug-drug interactions (DDI) that may result in high rates of hospital readmissions.
Chahed, S. +4 more
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Frontiers in Microbiology, 2021 Understanding interactions between antibiotics used in combination is an important theme in microbiology. Using the interactions between the antifolate drug trimethoprim and the ribosome-targeting antibiotic erythromycin in Escherichia coli as a model ...
Qin Qi +4 more
doaj +1 more source
Drug-drug interactions in the hospital [PDF]
, 2007 Introduction Drug interaction screening programs are an important tool to check prescriptions of multiple drugs for potential drug-drug interactions (pDDIs). Several programs are available on the market.
Vonbach, Priska
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INNOVATIONS in Pharmacy, 2022 Background: Pharmacogenomics (PGx) can provide more precision in determining causation of adverse drug reactions (ADRs) from drug-drug-gene interaction clinical application.
Jade Nanan +2 more
doaj +1 more source
High-throughput profiling of drug interactions in Gram-positive bacteria [PDF]
, 2021 Antimicrobial resistance is an increasingly serious threat that influences all domains of modern medicine and public health. Many strategies are currently implemented to counteract its spread and tackle resistant strains.
Cacace, Elisabetta; id_orcid +2 more
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Drug–Drug–Gene Interactions in Cardiovascular Medicine
Pharmacogenomics and Personalized Medicine, 2022 Innocent G Asiimwe, Munir Pirmohamed The Wolfson Centre for Personalized Medicine, MRC Centre for Drug Safety Science, Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool ...
Asiimwe IG, Pirmohamed M
doaj
Protein-Ligand Interactions and Drug Design
, 2021 This detailed book collects modern and established computer-based methods aimed at addressing the drug discovery challenge from disparate perspectives by exploiting information on ligand-protein recognition.
Ballante, Flavio,
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Model Informed Drug Development and Precision Dosing for Drug-Drug-Gene-Interactions: Application of Physiologically-Based Pharmacokinetic Modeling [PDF]
, 2021 The global demand for pharmaceuticals is continuously growing. As a result, one can observe an increase in adverse drug reactions, which pose a critical risk to patients.
Wojtyniak, Jan-Georg
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Multimorbidity, polypharmacy, and drug-drug-gene interactions following a non-ST elevation acute coronary syndrome: analysis of a multicentre observational study. [PDF]
BMC Med, 2020 Background: The number of patients living with co-existing diseases is growing. This study aimed to assess the extent of multimorbidity, medication use, and drug- and gene-based interactions in patients following a non-ST elevation acute coronary ...
Turner RM +4 more
europepmc +2 more sources
Gene based message passing for drug repurposing [PDF]
, 2023 Summary: The medicinal effect of a drug acts through a series of genes, and the pathological mechanism of a disease is also related to genes with certain biological functions. However, the complex information between drug or disease and a series of genes
Zhiming Dai +9 more
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