Results 31 to 40 of about 7,761,818 (273)
DGIdb 3.0: a redesign and expansion of the drug–gene interaction database [PDF]
Nucleic Acids Research, 2017 ABSTRACT The Drug-Gene Interaction Database (DGIdb, www.dgidb.org ) consolidates, organizes, and presents drug-gene interactions and gene druggability information from papers, databases, and web resources.
Kelsy C Cotto +9 more
openaire +3 more sources
Drug-drug interactions in the hospital [PDF]
, 2007 Introduction Drug interaction screening programs are an important tool to check prescriptions of multiple drugs for potential drug-drug interactions (pDDIs). Several programs are available on the market.
Vonbach, Priska
core +1 more source
Frontiers in Microbiology, 2021 Understanding interactions between antibiotics used in combination is an important theme in microbiology. Using the interactions between the antifolate drug trimethoprim and the ribosome-targeting antibiotic erythromycin in Escherichia coli as a model ...
Qin Qi +4 more
doaj +1 more source
CYP2C19 drug-drug and drug-gene interactions in ED patients. [PDF]
Am J Emerg Med, 2016 CYP450 polymorphisms result in variable rates of drug metabolism. CYP drug-drug interactions can contribute to altered drug effectiveness and safety.The primary objective was to determine the percentage of emergency department (ED) patients with cytochrome 2C19 (CYP2C19) drug-drug interactions. The secondary objective was to determine the prevalence of
Flaten HK +4 more
europepmc +4 more sources
High-throughput profiling of drug interactions in Gram-positive bacteria [PDF]
, 2021 Antimicrobial resistance is an increasingly serious threat that influences all domains of modern medicine and public health. Many strategies are currently implemented to counteract its spread and tackle resistant strains.
Cacace, Elisabetta; id_orcid +2 more
core +1 more source
Drug–Drug–Gene Interactions in Cardiovascular Medicine
Pharmacogenomics and Personalized Medicine, 2022 Innocent G Asiimwe, Munir Pirmohamed The Wolfson Centre for Personalized Medicine, MRC Centre for Drug Safety Science, Department of Pharmacology and Therapeutics, Institute of Systems, Molecular and Integrative Biology, University of Liverpool ...
Asiimwe IG, Pirmohamed M
doaj
INNOVATIONS in Pharmacy, 2022 Background: Pharmacogenomics (PGx) can provide more precision in determining causation of adverse drug reactions (ADRs) from drug-drug-gene interaction clinical application.
Jade Nanan +2 more
doaj +1 more source
Protein-Ligand Interactions and Drug Design
, 2021 This detailed book collects modern and established computer-based methods aimed at addressing the drug discovery challenge from disparate perspectives by exploiting information on ligand-protein recognition.
Ballante, Flavio,
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Functional drug–gene interactions in lung cancer
Expert Review of Molecular Diagnostics, 2012 Despite the dawn of the genomic information era, the challenges of cancer treatment remain formidable. Particularly for the most prevalent cancer types, including lung cancer, successful treatment of metastatic disease is rare and escalating costs for modern targeted drugs place an increasing strain on healthcare systems.
Smida, M, Nijman, S
openaire +2 more sources
Model Informed Drug Development and Precision Dosing for Drug-Drug-Gene-Interactions: Application of Physiologically-Based Pharmacokinetic Modeling [PDF]
, 2021 The global demand for pharmaceuticals is continuously growing. As a result, one can observe an increase in adverse drug reactions, which pose a critical risk to patients.
Wojtyniak, Jan-Georg
core +1 more source