Results 101 to 110 of about 12,201 (250)
Liver organoids: From 3D printing to biomedical applications
BMEMat, EarlyView.A comprehensive review on liver organoids culture techniques from 3D printing to organ‐on‐chip, as well as focusing on challenges and perspectives for advancement liver organoids in various future applications. Abstract The liver is an immune organ, especially an immune tolerance organ.
Ying Shi +4 more
wiley +1 more source
Hepatic macrophages in drug-induced liver injury
Liver Research, 2019 Drug-induced liver injury (DILI) is a major public health concern. Intrinsic DILI, for example, acetaminophen overdose accounts for half of acute liver failure in the United States.
Zhao Shan, Cynthia Ju
doaj
A programmable actuator for combined motion and connection and its application to modular robot [PDF]
Mechatronics, Elsevier, 2019, 58, pp.9-19, 2019 This paper proposes a new type of actuator at millimeter scale, which is based on Simplified Electro-Permanent (SEP) magnets. The new actuator can achieve connection and smooth motion by controlling the polarity of SEP magnets. Analyses based on numerical simulation are used to design a prototype.
arxiv +1 more source
Comprehensive review of anti-tubercular treatment induced liver injury [PDF]
, 2017 The challenge in the management of tuberculosis is further compounded by the liver injury associated with anti-tubercular treatment (ATT) drugs. The problem of drug-induced liver injury (DILI) associated with ATT drugs is significant in the developing ...
Chakrawarty, Avinash +3 more
core +2 more sources
Organ‐on‐Chip: The Future of Nutrition Research in a One Health World
Food Frontiers, EarlyView.Organ‐on‐chips offer a promising tool for evaluating food and feed safety. Organ‐on‐chips also present a scientifically robust and ethical alternative to animal studies. ABSTRACT The One Health approach emphasizes the interconnectedness of human, animal, and environmental health, recognizing that the health of each is interdependent and influenced by ...
Manuela Cassotta +8 more
wiley +1 more source
The rediscovery of HepG2 cells for prediction of drug induced liver injury (DILI)
EXCLI journal, 2014 EXCLI Journal ; Vol.
openaire +4 more sources
Pregnane X receptor in drug-induced liver injury: Friend or foe?
Liver Research, 2018 The pregnane X receptor (PXR) is a ligand activated nuclear receptor that is highly expressed in the liver and regulates many cellular functions including drug metabolism, endobiotic metabolism, oxidative stress response, apoptosis, inflammation, cell ...
Amina I. Shehu, Xiaochao Ma
doaj
Frontiers in Pharmacology, 2020 Drug-induced liver injury (DILI) is one of the major reasons for termination of drug development. Due to the importance of predicting DILI in early phases of drug development, diverse in silico models have been developed to filter out DILI-causing ...
Hyun Kil Shin +7 more
doaj +1 more source
REMEDI: REinforcement learning-driven adaptive MEtabolism modeling of primary sclerosing cholangitis DIsease progression [PDF]
arXiv, 2023 Primary sclerosing cholangitis (PSC) is a rare disease wherein altered bile acid metabolism contributes to sustained liver injury. This paper introduces REMEDI, a framework that captures bile acid dynamics and the body's adaptive response during PSC progression that can assist in exploring treatments.
arxiv
Drug-induced liver injury [PDF]
, 2010 Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn Skoða/Opna(view/open)Drug-induced liver injury (DILI) is a well known adverse reaction of many drugs. Direct toxic liver damage is associated with paracetamol toxicity
Einar S. Björnsson
core