Results 101 to 110 of about 11,641 (246)

Case report: Kinetics of human leukocyte antigen receptor HLA-DR during liver injury induced by potassium para-aminobenzoate as assessed for causality using the updated RUCAM

Frontiers in Pharmacology, 2022
Potassium para-aminobenzoate (POTABA) is used to treat Peyronie’s disease by decreasing fibrosis and plaque size progression. Among potential side effects, drug-induced liver injury (DILI) attributed to POTABA administration has been reported in a few ...
Marlene Plüß, Désirée Tampe, Harald Schwörer, Sebastian Christopher Benjamin Bremer, Björn Tampe   +4 more
doaj   +1 more source

Drug Hepatotoxicity: Environmental Factors [PDF]

, 2017
Drug-induced liver injury presents as various forms of acute and chronic liver disease. There is wide geographic variation in the most commonly implicated agents.
Chalasani, Naga P., Stine, Jonathan G.
core   +1 more source

Drugs-induced liver injury associated with non-steroidal anti-inflammatory drugs: a case report and clinical insights

Alʹmanah Kliničeskoj Mediciny, 2019
Aim: To raise the awareness of general practitioners with special characteristics of the clinical manifestations of the drug-induced liver injury (DILI), which can manifest with various signs, symptoms and types of morphological injury, from asymptomatic
Yu. G. Sandler, E. V. Vinnitskaya, K. G. Saliev, S. G. Khomeriki, T. Yu. Кhaimenova   +4 more
doaj   +1 more source

Utility of Liver Biopsy in the Diagnosis and Management of Possible Drug-Induced Liver Injury in Patients Receiving Antituberculosis Therapy: A Retrospective Study

Infectious Disease Reports, 2023
Background: Drug-induced liver injury (DILI) secondary to ATT treatment (TB-DILI) is reported in 2–28% of patients. We present here a series of clinical cases of suspected DILI arising during antituberculosis treatment, studied with the aid of liver ...
Gina Gualano, Drieda Zace, Silvia Mosti, Paola Mencarini, Maria Musso, Raffaella Libertone, Carlotta Cerva, Delia Goletti, Alessia Rianda, Franca Del Nonno, Laura Falasca, Fabrizio Palmieri   +11 more
doaj   +1 more source

Progress in the treatment of drug-induced liver injury with natural products

Pharmacological Research, 2022
There are numerous prescription drugs and non-prescription drugs that cause drug-induced liver injury (DILI), which is the main cause of liver disease in humans around the globe. Its mechanism becomes clearer as the disease is studied further.
Yuan-kai Sun, Ya-fei Zhang, Li Xie, Fan Rong, Xing-yu Zhu, Jing Xie, Huan Zhou, Tao Xu   +7 more
doaj   +1 more source

In Vitro Assessment of Drug‐Induced Liver Injury Using Three‐Dimensional Cultured HepaSH Cells Derived From Chimeric Mouse Model With Humanized Liver

Journal of Applied Toxicology, EarlyView.
ABSTRACT Drug‐induced liver injury (DILI) is a serious adverse event and a common cause of postmarketing drug withdrawal. Despite nonclinical assessments of DILI risk, which are predominantly conducted in experimental animals, DILI remains a frequent adverse event, highlighting the need to improve nonclinical assessments.
Xingming Liu, Yuichiro Higuchi, Yuta Sakamoto, Shota Yanagida, Shotaro Uehara, Hiroshi Suemizu, Yasunari Kanda, Hiroyuki Kawagishi   +7 more
wiley   +1 more source

Severe drug-induced liver injury associated with prolonged use of Linezolid [PDF]

, 2010
This study aims to describe a patient developing concomitant severe liver failure and lactic acidosis after long-term treatment with linezolid. A 55-year-old Caucasian woman developed concomitant severe liver failure and lactic acidosis after a treatment
Benoit, Dominique, De Bus, Liesbet, Depuydt, Pieter, Libbrecht, Louis, NOLLET, JOKE, Van Vlierberghe, Hans, Vandekerckhove, Linos, Vogelaers, Dirk   +7 more
core   +1 more source

The rediscovery of HepG2 cells for prediction of drug induced liver injury (DILI)

EXCLI journal, 2014
EXCLI Journal ; Vol.
openaire   +4 more sources

Drug-induced liver injury: A primer for cardiologists

Journal of Clinical and Preventive Cardiology, 2022
Although drug-induced liver injury (DILI) is an uncommon diagnosis, it is an important cause of morbidity and mortality in hepatology practice. A timely diagnosis of DILI is important to stop causative drugs and keeping a high index of suspicion is ...
Narendra Singh Choudhary, Neeraj Saraf, Vinod Kumar, Manish Bansal, Ravi R Kasliwal   +4 more
doaj   +1 more source

Drug‐induced liver injury associated with selective androgen receptor modulators in an adolescent patient

JPGN Reports, EarlyView.
ABSTRACT Selective androgenic receptor modulators (SARMs) have similar properties to anabolic steroids but bind to androgen receptors in a tissue‐specific manner. Studies have investigated the benefits of SARMs in promoting bone and muscle growth while limiting the adverse effects of androgenic stimulation of other organs.
David J. Katibian, Laura E. Bauman, Katayoon Shayan, D. Brent Polk   +3 more
wiley   +1 more source