Results 131 to 140 of about 12,091 (224)

Helicobacter pylori Eradication Therapy–Associated Drug-Induced Liver Injury in a Patient With Primary Biliary Cholangitis

Gastro Hep Advances
Drug-induced liver injury (DILI) is a rare but serious complication of Helicobacter pylori eradication therapy, especially in patients with pre-existing liver disease. We report a 75-year-old man with well-controlled primary biliary cholangitis (PBC) who
Taro Nakajima, Takefumi Kimura, Yuki Yamashita, Yugo Iwaya, Tadanobu Nagaya, Hiromitsu Mori, Shuichi Wada   +6 more
doaj   +1 more source

EGCG inhibits ferroptosis to ameliorate APAP-induced liver injury by suppressing NEDD8 and stabilizing HUWE1 in vivo and in vitro

Acta Materia Medica
Excessive consumption of acetaminophen (APAP) has emerged as the primary culprit behind drug-induced liver injury (DILI), with N-acetylcysteine serving as the principal antidote.
Zijun Ouyang, Tao Zhang, Mengting Liu, Fufu Li, Hui Guo, Yanhui Li, Jieyu Chen, Feiyang Wang, Yang Sun, Dong Liu, Haiyan Sun   +10 more
doaj   +1 more source

Exploring drug-induced liver injury: comprehensive insights into mechanisms and management of hepatotoxic agents

Future Journal of Pharmaceutical Sciences
Background Drug-induced liver injury (DILI) is a significant adverse drug reaction, manifesting through a range of clinical presentations from mild liver enzyme to acute liver failure.
Ahmed K. Saleh, Thanaa A. El-Masry, Aya H. El-Kadem, Nada A. Ashour, Nageh A. El-Mahdy   +4 more
doaj   +1 more source

Drug induced liver injury (DILI) causes: Literatur review

Annals of Hepato-Biliary-Pancreatic Surgery, 2022
openaire   +1 more source

Guideline review: EASL clinical practice guidelines: drug-induced liver injury (DILI). [PDF]

Frontline Gastroenterol, 2022
Brennan PN, Cartlidge P, Manship T, Dillon JF.   +3 more
europepmc   +1 more source

Activation of Flucloxacillin-Specific CD8+ T-Cells With the Potential to Promote Hepatocyte Cytotoxicity in a Mouse Model [PDF]

, 2017
There are currently no animal models of drug-induced liver injury (DILI) where the adaptive immune system has been shown to damage the liver. Thus, it is difficult to explore the mechanistic basis of the tissue injury.
Antoine, Daniel J., Faulkner, Lee, Kenna, Gerry, Kipar, Anja, Naisbitt, Dean J., Nattrass, Ryan, Nicolas, Jean-Francois, Park, B. Kevin, Vocanson, Marc   +8 more
core  

Survival regression by data fusion [PDF]

, 2014
Any knowledge discovery could in principal benefit from the fusion of directly or even indirectly related data sources. In this paper we explore whether data fusion by simultaneous matrix factorization could be adapted for survival regression. We propose
Zitnik, Marinka, Zupan, Blaz
core  

Deriving time-concordant event cascades from gene expression data: A case study for Drug-Induced Liver Injury (DILI). [PDF]

PLoS Comput Biol, 2022
Liu A, Han N, Munoz-Muriedas J, Bender A.   +3 more
europepmc   +1 more source

Hepatotoxicity associated with statins: A retrospective pharmacovigilance study based on the FAERS database.

PLoS ONE
BackgroundStatins are commonly prescribed in clinical practice and are associated with a high risk of drug-induced liver injury (DILI). This study aims to examine the real-world data on statin-induced liver injury to assess medication safety.MethodsAll ...
Lu Zhou, Bin Wu, Yuan Bian, Yun Lu, Ya Zou, Shanshan Lin, Qinchuan Li, Chun Liu   +7 more
doaj   +1 more source

S2840 Drug-Induced Liver Injury (DILI) Secondary to Kratom Use

American Journal of Gastroenterology, 2021
Ali Wakil, Alsadiq Al-Hillan, Mujtaba Mohamed, Fayssa Salomon, Gopala Koneru   +4 more
openaire   +2 more sources