Results 131 to 140 of about 12,201 (250)

Incidence of drug-induced liver injury in medical inpatients [PDF]

, 2018
Objectives: Drug-induced liver injury (DILI) is a common concern. However, data on DILI epidemiology in inpatients are sparse. Methods: To investigate the incidence of DILI, we screened all patients in the pharmacoepidemiological inpatient database ...
Cavallaro, Marzia, Fattinger, Karin, Folkers, Gerd, Meier, Peter, Meier, Yvonne, Pauli-Magnus, Christiane, Roos, Malgorzata   +6 more
core  

Geniposidic Acid Targeting FXR “S332 and H447” Mediated Conformational Change to Upregulate CYPs and miR‐19a‐3p to Ameliorate Drug‐Induced Liver Injury

Advanced Science, Volume 12, Issue 15, April 17, 2025.
Drug abuse exacerbates cholesterol and bile acids burden, causing liver injury. Geniposidic acid targets FXR Ser332 and His447, together with SRC2‐3 recruitment and activated FXR nuclear translocation. Geniposidic acid‐activated FXR can upregulate CYPs to accelerate bile acids clearance and activate miR‐19a‐3p to suppress LXR‐mediated cholesterol ...
Minqi Fan, Yuanhang Xu, Bingxin Wu, Jiachan Long, Caihong Liu, Zuhui Liang, Rong Zhang, Zhongqiu Liu, Caiyan Wang   +8 more
wiley   +1 more source

Drug-induced liver injuries (Part 1)

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2012
The aim of review. To present modern concepts on mechanisms of drug-induced liver injury (DILI), to give their classification, to present approaches to disease diagnostics.Original positions.
S. F. Galimova
doaj  

Associations of gender and a proxy of female menopausal status with histological features of drug‐induced liver injury [PDF]

, 2017
Background & AimGender and menopause may contribute to type and severity of drug‐induced liver injury (DILI) by influencing host responses to injury. The aim of this study was to assess the associations of gender and female age 50 [a proxy of menopause ...
Ayako Suzuki, David E. Kleiner, Hans L. Tillmann, Herbert L. Bonkovsky, Huiman Barnhart, Jiezhun Gu, null null, Robert J. Fontana   +7 more
core   +1 more source

Psychedelic Drugs in Mental Disorders: Current Clinical Scope and Deep Learning‐Based Advanced Perspectives

Advanced Science, Volume 12, Issue 15, April 17, 2025.
Graphic illustration showing the strategic approaches based on the currently investigated evidence of psychedelics that suggests the challenges and how to address the prescription of mental disorders. These applicable avenues may provide substantial insight into distinguishing between brain networks and psychedelics.
Sung‐Hyun Kim, Sumin Yang, Jeehye Jung, Jeonghyeon Choi, Mingon Kang, Jae‐Yeol Joo   +5 more
wiley   +1 more source

Drug-Induced Liver Injury (DILI): A Major Challenge [PDF]

Drug Research, 2021
openaire   +2 more sources

Shape Detection of Liver From 2D Ultrasound Images [PDF]

arXiv, 2019
Applications of ultrasound images have expanded from fetal imaging to abdominal and cardiac diagnosis. Liver-being the largest gland in the body and responsible for metabolic activities requires to be to be diagnosed and therefore subject to utmost injury. Although, ultrasound imaging has developed into three and four dimensions providing higher amount
arxiv  

Incidence and prevalence of acute hepatitis E virus infection in patients with suspected Drug‐Induced Liver Injury in the Spanish DILI Registry [PDF]

, 2020
Judith Sanabria‐Cabrera, Rocío Sanjuán‐Jiménez, Encarnación Clavijo, Inmaculada Medina‐Cáliz, A. González-Jiménez, Miren García‐Cortés, Aida Ortega‐Alonso, Miguel Jiménez‐Pérez, Rocío González‐Grande, Camilla Stephens, Mercedes Robles‐Díaz, M. Isabel Lucena, Raúl J. Andrade   +12 more
openalex   +1 more source

Development of a Predictive Model for Classifying Immune Checkpoint Inhibitor‐Induced Liver Injury Types

JGH Open, Volume 9, Issue 4, April 2025.
ABSTRACT Aims Immune checkpoint inhibitors (ICIs) have transformed cancer therapy; however, they are associated with ICI‐induced liver injury (ICI‐LI), which manifests as hepatocellular, mixed, or cholestatic patterns with variable treatment responses.
Jun Kitadai, Toshifumi Tada, Takanori Matsuura, Mayumi Ehara, Tatsuya Sakane, Miki Kawano, Yuta Inoue, Shoji Tamura, Aya Horai, Yuuki Shiomi, Yoshihiko Yano, Yuzo Kodama   +11 more
wiley   +1 more source

Late-onset isavuconazole-induced liver injury

Medical Mycology Case Reports, 2018
Antifungal agents account for approximately 3% of Drug-Induced Liver Injury (DILI) cases. Isavuconazole is a novel triazole, and experience with long-term use of it is lacking.
Felix Bongomin, Isabel Rodriguez-Goncer, Carol Lorden, Akaninyene Otu, Rohit Bazaz   +4 more
doaj