Abstract The primary objective is to critically analyze approaches to local therapy for periodontal disease, particularly in light of its well‐established systemic implications. We specifically address common misconceptions and overestimations regarding the potential of local treatments in contrast to their actual clinical effectiveness.
Andrea Mombelli, Alkisti Zekeridou
wiley +1 more source
Antibiotic‐mediated immune modulation in periodontitis
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez +6 more
wiley +1 more source
Drug-Resistant Tuberculosis Outcomes in South Kivu Province, Democratic Republic of Congo, During a Humanitarian Crisis (2018-2024). [PDF]
Musafiri EM +7 more
europepmc +1 more source
The role of neutrophils in the pathophysiology of inflammatory bowel diseases
Abstract Objectives Inflammatory bowel disease (IBD) encompasses a spectrum of chronic disorders of the gastrointestinal tract, with a potential bidirectional relationship with periodontitis. Neutrophils are key regulators of immune‐inflammatory responses and play a major role in both diseases.
Joao Paulo Steffens +8 more
wiley +1 more source
ABSTRACT Background Tuberculous pleural effusion (TPE), the second most common form of extra‐pulmonary tuberculosis (TB), remains difficult to diagnose due to low‐yield, invasive and often unavailable diagnostics in resource‐limited settings. This study aimed to evaluate the diagnostic accuracy of sonographic characteristics alone to predict TB ...
Lukonde Zimba +3 more
wiley +1 more source
Drug-Resistant Tuberculosis in Prisons of Latin America and the Caribbean: A Critical Reflection on Structural Challenges and Gaps. [PDF]
Torres A, Trujillo G, Sánchez JD.
europepmc +1 more source
Assessment of Antimicrobial Resistance in M. leprae Strains From Kiribati
ABSTRACT Objectives Kiribati has one of the highest rates of leprosy worldwide. A nationwide screening and chemoprophylaxis program for household leprosy contacts was introduced in 2018. In 2022, population‐wide screening and rifamycin‐based treatment or chemoprophylaxis for leprosy and tuberculosis was introduced as part of the PEARL and COMBINE ...
Patrick O. Campbell +10 more
wiley +1 more source
Alleviating psychosocial distress in drug-resistant tuberculosis: a pre-post study on telephone-delivered motivational interviewing. [PDF]
Xie F, Xie E, Yang X, Wan B, Yao R.
europepmc +1 more source
ABSTRACT Objectives To describe the aetiology and antibiotic susceptibility patterns of common bacterial infections in hospitalised patients in Jakarta, Indonesia. Methods We conducted a hospital‐wide point prevalence survey in six hospitals in 2019, capturing data from routinely ordered bacterial cultures taken before the start of antibiotic treatment.
Justin de Brabander +36 more
wiley +1 more source
Targeted next-generation sequencing for direct drug-resistant tuberculosis detection in sputum samples in Indonesia: an implementation study (2024-25). [PDF]
Lestari BW +13 more
europepmc +1 more source

