Routine Molecular Surveillance of Drug-Resistant Tuberculosis: Translating Mutation Proxies into Clinical Governance Intelligence in Rural Eastern Cape. [PDF]
Sonka B +4 more
europepmc +1 more source
Clerodendrum infortunatum (Lamiaceae) is widely used in traditional medicine across South and Southeast Asia for the treatment of inflammation, fever, pain, and gastrointestinal disorders, yet its pharmacological efficacy and phytochemical basis remain inadequately validated by scientific research.
Mohi Uddin +6 more
wiley +1 more source
Orchestrating faster access to products of non-profit R&D: a case study of a novel regimen for drug-resistant tuberculosis. [PDF]
Moon S, Vieira MCF, Large K.
europepmc +1 more source
Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui +4 more
wiley +1 more source
Lineages of Mycobacterium tuberculosis complex associated with pulmonary drug-resistant tuberculosis in Africa: a systematic review. [PDF]
Gweba C +4 more
europepmc +1 more source
Epilepsy: Epidemiology, Molecular Pathogenesis, and Clinical Management
Epilepsy is a heterogeneous and chronically evolving brain network disorder. This review integrates epidemiological burden, psychiatric comorbidities, and cyclic seizure patterns with multiscale pathogenic mechanisms, including ion‐channel dysfunction, synaptic transmission defects, neuroinflammation, metabolic and mitochondrial dysfunction, and ...
Jian Liu +8 more
wiley +1 more source
Bedaquiline Resistance in Drug-Resistant Tuberculosis in South Africa: A Systematic Review and Meta-Analysis of Emerging Trends. [PDF]
Kaapu KG +3 more
europepmc +1 more source
The Dual Roles of Regulatory B Cells in Infection, Cancer, and Immunity
Regulatory B cells maintain immune homeostasis via suppressive cytokines and surface molecules like PD‐L1. While beneficially suppressing autoimmunity and promoting transplant tolerance, these identical mechanisms detrimentally attenuate antipathogen and antitumor immune responses.
Anni Feng +3 more
wiley +1 more source
Factors Influencing Early Sputum Culture Conversion in Pulmonary Drug-resistant Tuberculosis. [PDF]
Kotokey UK, Kumari S.
europepmc +1 more source
Weight Change Between Pregnancies and Mortality Over 50 Years of Follow‐Up
ABSTRACT Objective This study aimed to evaluate the link between postpartum weight retention (PPWR) and long‐term mortality. Methods In this secondary analysis of 8165 women with ≥ 2 pregnancies in the Collaborative Perinatal Project (CPP), U.S., 1959–1966, with vital status follow‐up through 2016, we used interconception weight change (ICWC) and ...
Yajnaseni Chakraborti +10 more
wiley +1 more source

