Results 1 to 10 of about 943,135 (348)
Review of Predicting Synergistic Drug Combinations [PDF]
Life, 2023 The prediction of drug combinations is of great clinical significance. In many diseases, such as high blood pressure, diabetes, and stomach ulcers, the simultaneous use of two or more drugs has shown clear efficacy. It has greatly reduced the progression
Yichen Pan +4 more
doaj +2 more sources
Drug combinations targeting antibiotic resistance [PDF]
npj Antimicrobials and ResistanceWhile the rise of antibiotic resistance poses a global health challenge, the development of new antibiotics has slowed down over the past decades. This turned the attention of researchers towards the rational design of drug combination therapies to ...
Bence Bognár +2 more
doaj +2 more sources
Candyflipping and Other Combinations: Identifying Drug–Drug Combinations from an Online Forum [PDF]
Frontiers in Psychiatry, 2018 Novel psychoactive substances (NPS) refer to synthetic compounds or derivatives of more widely known substances of abuse that have emerged over the last two decades. Case reports suggest that users combine substances to achieve desired psychotropic experiences while reducing dysphoria and unpleasant somatic effects.
David Yi, Michael Chary, Alex F. Manini
openaire +4 more sources
Network-based prediction of anti-cancer drug combinations [PDF]
Frontiers in PharmacologyDrug combinations have emerged as a promising therapeutic approach in cancer treatment, aimed at overcoming drug resistance and improving the efficacy of monotherapy regimens.
Jue Jiang +4 more
doaj +2 more sources
Synergistic and Antagonistic Drug Combinations Depend on Network Topology [PDF]
PLoS ONE, 2014 Drug combinations may exhibit synergistic or antagonistic effects. Rational design of synergistic drug combinations remains a challenge despite active experimental and computational efforts.
Lai, Luhua +5 more
core +5 more sources
piscesCSM: prediction of anticancer synergistic drug combinations [PDF]
Journal of CheminformaticsWhile drug combination therapies are of great importance, particularly in cancer treatment, identifying novel synergistic drug combinations has been a challenging venture.
Raghad AlJarf +4 more
doaj +2 more sources
Drug interactions and lethal drug combinations [PDF]
Journal of Clinical Pathology, 1975 A. Richens
openaire +5 more sources
Novel Synergistic Anti-Enteroviral Drug Combinations
Viruses, 2022 Background: Enterovirus infections affect people around the world, causing a range of illnesses, from mild fevers to severe, potentially fatal conditions. There are no approved treatments for enterovirus infections. Methods: We have tested our library of
Aleksandr Ianevski +7 more
doaj +1 more source
Corrigendum: Network-based prediction of anti-cancer drug combinations [PDF]
Frontiers in PharmacologyJue Jiang +4 more
doaj +2 more sources