Results 31 to 40 of about 1,946,248 (285)
Editorial: Drug Repurposing [PDF]
Frontiers in Medicine, 2019 Pan Pantziarka +5 more
doaj +4 more sources
Shotgun Drug Repurposing Biotechnology to Tackle Epidemics and Pandemics [PDF]
, 2020 In this manuscript we highlight consensus between the list of drugs currently in clinical trials to treat COVID-19, the worldwide pandemic caused by severe acute respiratory coronavirus 2 (SARS-CoV-2), and the list of predictions made using our shotgun ...
William, Mangione +4 more
core +1 more source
Drug repurposing for Alzheimer’s disease from 2012–2022—a 10-year literature review
Frontiers in Pharmacology, 2023 Background: Alzheimer’s disease (AD) is a debilitating neurodegenerative condition with few treatment options available. Drug repurposing studies have sought to identify existing drugs that could be repositioned to treat AD; however, the effectiveness of
Monika E. Grabowska +4 more
doaj +1 more source
Repurposing Drugs via Network Analysis: Opportunities for Psychiatric Disorders
Pharmaceutics, 2022 Despite advances in pharmacology and neuroscience, the path to new medications for psychiatric disorders largely remains stagnated. Drug repurposing offers a more efficient pathway compared with de novo drug discovery with lower cost and less risk ...
Trang T. T. Truong +3 more
doaj +1 more source
A data-driven methodology towards evaluating the potential of drug repurposing hypotheses
Computational and Structural Biotechnology Journal, 2021 Drug repurposing has become a widely used strategy to accelerate the process of finding treatments. While classical de novo drug development involves high costs, risks, and time-consuming paths, drug repurposing allows to reuse already-existing and ...
Lucía Prieto Santamaría +5 more
doaj +1 more source
Gene based message passing for drug repurposing [PDF]
, 2023 Summary: The medicinal effect of a drug acts through a series of genes, and the pathological mechanism of a disease is also related to genes with certain biological functions. However, the complex information between drug or disease and a series of genes
Zhiming Dai +9 more
core +1 more source
Drug Repurposing in Parkinson’s Disease [PDF]
CNS Drugs, 2018 The development of an intervention to slow or halt disease progression remains the greatest unmet therapeutic need in Parkinson's disease. Given the number of failures of various novel interventions in disease-modifying clinical trials in combination with the ever-increasing costs and lengthy processes for drug development, attention is being turned to
Athauda, D, Foltynie, T
openaire +3 more sources
Drug repurposing: Misconceptions, challenges, and opportunities for academic researchers
, 2021 Drug repurposing is promoted as a cost- and time-effective mechanism for providing new medicines. Often, however, there is insufficient consideration by academic researchers of the processes required to ensure that a repurposed drug can be used for a new
Baell, Jonathan +14 more
core +2 more sources
, 2023 Code used for data analysis of drug repurposing approach to target inflammation in ...
kravneet
core +1 more source
Considerations and challenges for sex-aware drug repurposing
Biology of Sex Differences, 2022 Highlights Genetic, epigenetic, hormonal, immunological, metabolic, and environmental factors affect sex-biased drug responses. Drug repurposing approaches provide a significant advantage over novel drug development by reducing lengthy and costly ...
Jennifer L. Fisher +5 more
doaj +1 more source