Results 41 to 50 of about 45,299 (154)
Artificial intelligence in COVID-19 drug repurposing
The Lancet: Digital Health, 2020 Summary: Drug repurposing or repositioning is a technique whereby existing drugs are used to treat emerging and challenging diseases, including COVID-19.
Yadi Zhou, PhD +4 more
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Pharmacology Research & PerspectivesDrug repurposing is an authentic, emerging, and growing aspect of drug development when the demand for new therapeutic solutions is high. Many repurposed drugs have been discovered by serendipity or a non‐ordered process driven by chance and sharp ...
Richard Head +2 more
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Protein sequence analysis in the context of drug repurposing
BMC Medical Informatics and Decision MakingMotivation Drug repurposing speeds up the development of new treatments, being less costly, risky, and time consuming than de novo drug discovery. There are numerous biological elements that contribute to the development of diseases and, as a result, to ...
Natalia García Sánchez +3 more
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Literature data-based de novo candidates for drug repurposing
BMC BioinformaticsBackground Drug repurposing offers a promising strategy for drug discovery. Drug repurposing involves identifying new therapeutic indications for existing, marketed drugs, thereby reducing the risks, costs, and time typically required for drug ...
Xianglong Liang, Xin Jiang, Yifang Ma
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Drug repurposing in cardiology [PDF]
Netherlands Heart Journal, 2020 van Driel, B. O., van der Velden, J.
openaire +3 more sources
A bibliometric review of drug repurposing [PDF]
Drug Discovery Today, 2018 We have conducted a bibliometric review of drug repurposing by scanning >25 million papers in PubMed and using text-mining methods to gather, count and analyze chemical-disease therapeutic relationships. We find that >60% of the ~35,000 drugs or drug candidates identified in our study have been tried in more than one disease, including 189 drugs that ...
Nancy C, Baker +3 more
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Trends in drug repurposing for chronic hepatitis-B infection: Bibliometric-based approach 1990-2024 [PDF]
BIO Web of ConferencesChronic hepatitis B (CHB) infection is still a world problem today, especially in the developing countries. Until now, treatment related to CHB is still being continuously pursued using a variety of the latest approaches.
Irham Lalu Muhammad +6 more
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Clinical and Translational MedicinePurpose Systematic repurposing of approved medicines for another indication may accelerate drug development in oncology. We present a strategy combining biomarker testing with drug repurposing to identify new treatments for patients with advanced cancer.
Imogen R. Walpole +8 more
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BMC GenomicsBackground Drug repurposing plays a significant role in providing effective treatments for certain diseases faster and more cost-effectively. Successful repurposing cases are mostly supported by a classical paradigm that stems from de novo drug ...
Belén Otero-Carrasco +5 more
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Drug repurposing for rare: progress and opportunities for the rare disease community
Frontiers in MedicineRepurposing is one of the key opportunities to address the unmet rare diseases therapeutic need. Based on cases of drug repurposing in small population conditions, and previous work in drug repurposing, we analyzed the most important lessons learned ...
Anneliene Hechtelt Jonker +19 more
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