Results 11 to 20 of about 543,044 (334)
Hsp90 governs dispersion and drug resistance of fungal biofilms. [PDF]
PLoS Pathogens, 2011 Fungal biofilms are a major cause of human mortality and are recalcitrant to most treatments due to intrinsic drug resistance. These complex communities of multiple cell types form on indwelling medical devices and their eradication often requires ...
Nicole Robbins +7 more
doaj +21 more sources
Fungal Biofilms and Drug Resistance
Emerging Infectious Diseases, 2004 Candida species, including the novel opportunistic pathogen Candida dubliniensis, are now emerging as major agents of nosocomial infections. Many such manifestations of infections associated with the formation of Candida biofilms include those occurring ...
Mary Ann Jabra-Rizk +2 more
doaj +6 more sources
Development and research progress of anti-drug resistant fungal drugs
Journal of Infection and Public Health, 2022 With the widespread use of immunosuppressive agents and the increase in patients with severe infections, the incidence of fungal infections worldwide has increased year by year.
Xiangyi Cui +3 more
doaj +3 more sources
Prevalence and Therapeutic Challenges of Fungal Drug Resistance: Role for Plants in Drug Discovery [PDF]
Antibiotics, 2020 Antimicrobial resistance is a global issue that threatens the effective practice of modern medicine and global health. The emergence of multidrug-resistant (MDR) fungal strains of Candida auris and azole-resistant Aspergillus fumigatus were highlighted ...
L. Marquez, C. Quave
semanticscholar +4 more sources
Sphingolipids: Regulators of azole drug resistance and fungal pathogenicity
Molecular Microbiology, 2020 In recent years, the role of sphingolipids in pathogenic fungi, in terms of pathogenicity and resistance to azole drugs, has been a rapidly growing field.
Jinxing Song, Xiao Liu, Rongpeng Li
semanticscholar +4 more sources
Virulence Regulation and Drug-Resistance Mechanism of Fungal Infection
Microorganisms, 2022 In this issue, I propose promising developments in the field of the mechanism of virulence factors that can be linked to antifungal resistance [...]
Letizia Angiolella
doaj +3 more sources
The Fungal CYP51s: Their Functions, Structures, Related Drug Resistance, and Inhibitors [PDF]
Frontiers in Microbiology, 2019 CYP51 (Erg11) belongs to the cytochrome P450 monooxygenase (CYP) superfamily and mediates a crucial step of the synthesis of ergosterol, which is a fungal-specific sterol. It is also the target of azole drugs in clinical practice.
Jingxiang Zhang +5 more
semanticscholar +5 more sources
KAJIAN MOLEKULER RESISTENSI Candida albicans TERHADAP ANTIFUNGI [PDF]
Jurnal Farmasi Sains dan Komunitas, 2014 : Candida albicans is one of the species Candida which mostly cause infection in human. Antifungal agent azole, polyene, echinocandin, and flucytosine are commonly used for Candida albicans infection treatment.
Damiana Sapta Candrasari
doaj +5 more sources
Candida auris: An Overview of the Emerging Drug-Resistant Fungal Infection
Infection & Chemotherapy, 2022 Candida auris is an invasive fungal pathogen that has been recognized globally as a serious health threat due to its extensive innate and acquired resistance to antifungal drugs. A growing number of emerging cases of C.
A. Sanyaolu +8 more
semanticscholar +3 more sources
Deciphering the role of mitochondria in human fungal drug resistance
MycologyAs pathogenic fungi increasingly threaten public health, particularly in immunocompromised populations, understanding the mechanisms behind fungal drug resistance has become critical.
Yuanyuan Ma +5 more
doaj +2 more sources