Results 31 to 40 of about 4,538,104 (325)

Antifungal resistance in dermatology

Indian Journal of Dermatology, 2018
Cutaneous fungal infections affect more than one-fourth of world's population. The pathogenesis and severity of fungal infection depend on various immunological and nonimmunological factors.
Varadraj Pai, Ajantha Ganavalli, Naveen Narayanshetty Kikkeri   +2 more
doaj   +1 more source

Fungal biofilm resistance [PDF]

, 2012
Fungal biofilm infections have become increasingly recognised as a significant clinical problem. One of the major reasons behind this is the impact that these have upon treatment, as antifungal therapy often fails and surgical intervention is required ...
Ramage, Gordon, Williams, Craig, Rajendran, Ranjith, Ranjith Rajendran, Gordon Ramage, Leighann Sherry, Sherry, Leighann, Craig Williams   +7 more
core   +1 more source

Exploring hidden dimensions of soil fungal biodiversity: A simple technique to detect soil fungi resistant to antifungal compounds [PDF]

, 2010
Soils are known to be ultimate and complex reservoirs of microbial diversity. The complex dimensions of bacterial and fungal diversity in tropical soils and microbial community dynamics are underexplored.
Sonashia Velho-Pereira, Nandkumar M. Kamat   +1 more
core   +1 more source

The Quiet and Underappreciated Rise of Drug-Resistant Invasive Fungal Pathogens [PDF]

Journal of Fungi, 2020
Human fungal pathogens are attributable to a significant economic burden and mortality worldwide. Antifungal treatments, although limited in number, play a pivotal role in decreasing mortality and morbidities posed by invasive fungal infections (IFIs). However, the recent emergence of multidrug-resistant Candida auris and Candida glabrata and acquiring
Amir Arastehfar, Cornelia Lass-Flörl, Rocio Garcia-Rubio, Farnaz Daneshnia, Macit Ilkit, Teun Boekhout, Toni Gabaldon, David S. Perlin   +7 more
openaire   +5 more sources

Repurposing FDA-Approved Drugs to Inhibit Fungal PPTases for Broad-Spectrum Synergy. [PDF]

Adv Sci (Weinh)
Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Song Z, Zhao C, Wang Q, Zhang H, Liu X, Wang L, Bromley M, Yin WB.   +7 more
europepmc   +2 more sources

Fungicide-driven evolution and molecular basis of multidrug resistance in field populations of the grey mould fungus Botrytis cinerea [PDF]

, 2009
The grey mould fungus Botrytis cinerea causes losses of commercially important fruits, vegetables and ornamentals worldwide. Fungicide treatments are effective for disease control, but bear the risk of resistance development.
Pradier Jean-Marc, Pradier, J.M., Walker, Anne-Sophie, Mernke, Dennis, Pradier, Jean Marc, J. M., Leroux, Pierre, Matthias Hahn, Matthias Kretschmer, Sabine Fillinger, Walker, Anne Sophie, Kretschmer, M., Hahn, Matthias, Fillinger Sabine, Jean-Marc Pradier, Mosbach, Andreas, Walker, A.S., Mernke, Denis, Kretschmer Matthias, Mernke, D., Fillinger, S., de Waard, Maarten A, Maarten A De Waard, Walker, Anne Sophie, A. S., Leroux, P., de Waard, M.A., De Waard Maarten A., Leroux Pierre, Fillinger-David, Sabine, Helma, S. H., Anne-Sophie Walker, Pierre Leroux, Waard, Maarten A. De, Schoonbeek, Henk-jan, Leroch, Michaela, Leroch, M., Pradier, Jean Marc, Leroux, Pierre, P., Mosbach, A., Waard, M.A., de, Dennis Mernke, Pradier, Jean-Marc, Hahn Matthias, Leroch Michaela, Walker Anne-Sophie, Schoonbeek Henk-Jan, Fillinger-David, Sabine, Helma, Henk-Jan Schoonbeek, Mernke Dennis, Fillinger, Sabine, Mosbach Andreas, Andreas Mosbach, Michaela Leroch, Kretschmer, Matthias, Schoonbeek, H.J., Hahn, M.   +53 more
core   +1 more source

Molecular mechanisms governing antifungal drug resistance

npj antimicrobials and resistance, 2023
Fungal pathogens are a severe public health problem. The leading causative agents of systemic fungal infections include species from the Candida, Cryptococcus, and Aspergillus genera.
Yunjin Lee, Nicole Robbins, L. Cowen
semanticscholar   +1 more source

Coordination of fungal biofilm development by extracellular vesicle cargo

Nature Communications, 2021
The fungal pathogen Candida albicans can release extracellular vesicles that promote biofilm formation and antifungal resistance. Here, Zarnowski et al.
Robert Zarnowski, Andrea Noll, Marc G. Chevrette, Hiram Sanchez, Ryley Jones, Hanna Anhalt, Jen Fossen, Anna Jaromin, Cameron Currie, Jeniel E. Nett, Aaron Mitchell, David R. Andes   +11 more
doaj   +1 more source

Psychogenetic, genetic and epigenetic mechanisms in Candida auris: Role in drug resistance

Journal of Infection and Public Health, 2023
In recent years, we are facing the challenge of drug resistance emergence in fungi. The availability of limited antifungals and development of multi-drug resistance in fungal pathogens has become a serious concern in the past years in the health sector ...
Ali A. Rabaan, Khalid Eljaaly, Wadha A. Alfouzan, Abbas Al Mutair, Saad Alhumaid, Amal H. Alfaraj, Yahya Aldawood, Abdulmonem A. Alsaleh, Hawra Albayat, Reyouf Al Azmi, Nawal AlKaabi, Samira J. Alzahrani, Salma AlBahrani, Tarek Sulaiman, Abeer N. Alshukairi, Abdulmonem A. Abuzaid, Mohammed Garout, Rafiq Ahmad, Javed Muhammad   +18 more
doaj   +1 more source

Antifungal Drug Resistance: An Emergent Health Threat

Biomedicines, 2023
Fungal infections, named mycosis, can cause severe invasive and systemic diseases that can even lead to death. In recent years, epidemiological data have recorded an increase in cases of severe fungal infections, caused mainly by a growing number of ...
A. Vitiello, F. Ferrara, M. Boccellino, Annarita Ponzo, Carla Cimmino, Emilio Comberiati, A. Zovi, Salvatore Clemente, M. Sabbatucci   +8 more
semanticscholar   +1 more source