Fungicide-driven evolution and molecular basis of multidrug resistance in field populations of the grey mould fungus Botrytis cinerea [PDF]
The grey mould fungus Botrytis cinerea causes losses of commercially important fruits, vegetables and ornamentals worldwide. Fungicide treatments are effective for disease control, but bear the risk of resistance development.
Pradier Jean-Marc +53 more
core +1 more source
Global analysis of the evolution and mechanism of echinocandin resistance in Candida glabrata. [PDF]
The evolution of drug resistance has a profound impact on human health. Candida glabrata is a leading human fungal pathogen that can rapidly evolve resistance to echinocandins, which target cell wall biosynthesis and are front-line therapeutics for ...
Sheena D Singh-Babak +9 more
doaj +1 more source
Synergy in efficacy of fungal entomopathogens and permethrin against West African insecticide-resistant Anopheles gambiae mosquitoes. [PDF]
BACKGROUND: Increasing incidences of insecticide resistance in malaria vectors are threatening the sustainable use of contemporary chemical vector control measures.
Knols, B.G.J. +31 more
core +2 more sources
Stress, Drugs, and Evolution: the Role of Cellular Signaling in Fungal Drug Resistance [PDF]
The survival of all organisms depends critically upon interactions with the environment, mediated largely through the action of small molecules. Small molecules can provide the nutrients to support life ([195][1]), mediate communication between organisms ([25][2], [76][3], [238][4]), or ...
Leah E, Cowen, William J, Steinbach
openaire +2 more sources
Prevalence and Therapeutic Challenges of Fungal Drug Resistance: Role for Plants in Drug Discovery [PDF]
Antimicrobial resistance is a global issue that threatens the effective practice of modern medicine and global health. The emergence of multidrug-resistant (MDR) fungal strains of Candida auris and azole-resistant Aspergillus fumigatus were highlighted in the Centers for Disease Control and Prevention’s (CDC) 2019 report, Antibiotic Resistance Threats ...
Lewis Marquez, Cassandra L. Quave
openaire +3 more sources
Explaining risk factors for drug-resistant tuberculosis in England and Wales: contribution of primary and secondary drug resistance [PDF]
Drug-resistant tuberculosis can be transmitted (primary) or develop during the course of treatment (secondary). We investigated risk factors for each type of resistance.
Glynn, JR +5 more
core +1 more source
In vitro susceptibility of Cuban Aspergillus spp. strains of clinical and environmental origin
Introduction: The behavior of antifungal susceptibility of Aspergillus spp. in Cuba remains unknown. The antifungals recommended to treat aspergillosis are amphotericin B, itraconazole, voriconazole and echinocandins. The influence of the environment may
Javier L. San Juan +6 more
doaj +1 more source
Linking calcium signaling and mitochondrial function in fungal drug resistance [PDF]
The host range for Aspergillus fumigatus is wide, including mammals, aves, and insecta (stonebrood). This is linked to the significant adaptability of this important fungal pathogen. It is thermotolerant, able to grow up to 70 °C, and astonishingly also remains viable down to −20 °C (1).
Paul Bowyer +2 more
openaire +3 more sources
Development of Fungal Applications on Netting Substrates for Malaria Vector Control [PDF]
Mosquito resistance to chemical insecticides is considered a serious threat for the sustainable use of contemporary malaria vector control methods.
Knols, B.G.J. +3 more
core +1 more source
Drug induced tolerance mechanisms of the fungal pathogen Candida albicans [PDF]
Candida albicans is a fungal pathogen that already has described mechanisms of resistance. Here we describe mechanisms of drug tolerance.
Mark Peacock (21038903)
core +5 more sources

