Results 41 to 50 of about 4,538,104 (325)

Drug resistance with monitored adherence [PDF]

, 2013
Drug resistance can be defined as the failure of a drug to exert its expected effect on pharmacological biomarkers and is caused by pharmacogenetic, cellular or clinical factors.
Walter, Philipp Niklaus
core   +1 more source

Efficacy of Gold Nanoparticles against Drug-Resistant Nosocomial Fungal Pathogens and Their Extracellular Enzymes: Resistance Profiling towards Established Antifungal Agents

Nanomaterials, 2022
Drug resistance of filamentous fungi to the commonly used antifungal agents is a major concern in medicine. Therefore, an effective approach to treat several opportunistic fungal infections is the need of the hour.
A. Almansob, A. Bahkali, Fuad Ameen
semanticscholar   +1 more source

Reverse genetics in Candida albicans predicts ARF cycling is essential for drug resistance and virulence [PDF]

, 2010
Peer ...
Mullick, Alaka, Malcolm Whiteway, Jansen, Gregor, Whiteway, Malcolm, David Y Thomas, Harcus Doreen, Lee Anna Y., Vanier, Ghyslaine, Lee, Anna Y., Thomas, David Y, Michael Hallett, Vanier Ghyslaine, Munro, Carol A., Elias Epp, Epp Elias, Gregor Jansen, Thomas, David Y., Ghyslaine Vanier, Jansen Gregor, Harcus, Doreen, Anna Y Lee, Alaka Mullick, Hallett, Michael, Lee, Anna Y, Thomas David Y., Hallett Michael, Whiteway Malcolm, Carol A Munro, Mullick Alaka, Epp, Elias, Don C Sheppard, Sheppard Don C., Munro Carol A., Doreen Harcus, Sheppard, Don C, Sheppard, Don C., Munro, Carol A   +36 more
core   +1 more source

Lipid Flippase Subunit Cdc50 Mediates Drug Resistance and Virulence in Cryptococcus neoformans

mBio, 2016
Cryptococcus neoformans is a human fungal pathogen and a major cause of fungal meningitis in immunocompromised individuals. Treatment options for cryptococcosis are limited.
Wei Huang, Guojian Liao, Gregory M. Baker, Yina Wang, Richard Lau, Padmaja Paderu, David S. Perlin, Chaoyang Xue   +7 more
doaj   +1 more source

Synergy in efficacy of fungal entomopathogens and permethrin against West African insecticide-resistant Anopheles gambiae mosquitoes. [PDF]

, 2010
BACKGROUND: Increasing incidences of insecticide resistance in malaria vectors are threatening the sustainable use of contemporary chemical vector control measures.
Knols, B.G.J., Mark Rowland, Annabel F V Howard, Farenhorst, Marit, Knols, Bart G. J., N’Guessan Raphael, N'Guessan, R., Howard, A.F.V., Thomas, Matthew B., Annabel F. V. Howard, Rowland Mark, Knols, Bart GJ, Farenhorst, M., N'Guessan, Raphael, Takken, W., Thomas Matthew B., Raphael N’Guessan, Farenhorst Marit, Howard Annabel F. V., Rowland, Mark, Howard, Annabel F. V., Matthew B. Thomas, Thomas, Matthew B, Howard, Annabel FV, Takken, Willem, Takken Willem, Knols Bart G. J., Thomas, M.B., Matthew B Thomas, Rowland, M., Raphael N'Guessan, Marit Farenhorst, Bart G. J. Knols, Bart G J Knols, Willem Takken   +34 more
core   +3 more sources

Spread of anti-malarial drug resistance: mathematical model with implications for ACT drug policies. [PDF]

, 2008
BACKGROUND: Most malaria-endemic countries are implementing a change in anti-malarial drug policy to artemisinin-based combination therapy (ACT). The impact of different drug choices and implementation strategies is uncertain.
Hastings, Ian M, Day, Nicholas PJ, White, Nicholas J., Dondorp, AM, Hastings, Ian M., Dondorp, Arjen M, Dondorp, Adrianus, Hastings, Ian, Day, Nicholas P. J., Pongtavornpinyo, W, Hastings, IM, Pongtavornpinyo, Wirichada, White, Nicholas J, Day, Nicholas, Day, Nicholas P.J., Yeung, Shunmay, Day, NP, White, NJ, White, Nicholas, Dondorp, Arjen M., Yeung, S, Hastings Ian M, Dondorp Arjen M, Pongtavornpinyo Wirichada, Day Nicholas PJ, Yeung Shunmay, White Nicholas J   +26 more
core   +1 more source

Stress, Drugs, and Evolution: the Role of Cellular Signaling in Fungal Drug Resistance [PDF]

Eukaryotic Cell, 2008
The survival of all organisms depends critically upon interactions with the environment, mediated largely through the action of small molecules. Small molecules can provide the nutrients to support life ([195][1]), mediate communication between organisms ([25][2], [76][3], [238][4]), or ...
Leah E, Cowen, William J, Steinbach
openaire   +2 more sources

Global analysis of the evolution and mechanism of echinocandin resistance in Candida glabrata. [PDF]

PLoS Pathogens, 2012
The evolution of drug resistance has a profound impact on human health. Candida glabrata is a leading human fungal pathogen that can rapidly evolve resistance to echinocandins, which target cell wall biosynthesis and are front-line therapeutics for ...
Sheena D Singh-Babak, Tomas Babak, Stephanie Diezmann, Jessica A Hill, Jinglin Lucy Xie, Ying-Lien Chen, Susan M Poutanen, Robert P Rennie, Joseph Heitman, Leah E Cowen   +9 more
doaj   +1 more source

Hsp21potentiates antifungal drug tolerance in Candida albicans [PDF]

, 2013
Peer ...
Hube Bernhard, Wilson Duncan, Duncan Wilson, Bernhard Hube, Mayer, François L, Hube, Bernhard, Mayer François L., Wilson, Duncan, François L Mayer   +8 more
core   +2 more sources

Development of Fungal Applications on Netting Substrates for Malaria Vector Control [PDF]

, 2011
Mosquito resistance to chemical insecticides is considered a serious threat for the sustainable use of contemporary malaria vector control methods.
Thomas, Matthew B., Knols, B.G.J., Hilhorst, Anne, Farenhorst, M., Farenhorst, Marit, Knols, Bart G. J., Hilhorst, A., Thomas, M.B.   +7 more
core   +1 more source