Results 41 to 50 of about 4,366,481 (288)
Drug Resistance and Evolvability in an Emerging Human Fungal Pathogen
mBio, 2022 Over the past decade, Candida auris has emerged as a highly transmissible human fungal pathogen. Because of its ability to transmit between patients in hospitals and its ability to rapidly develop drug resistance, C. auris presents unique challenges.
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Antifungals and Drug Resistance
Encyclopedia, 2022 Antifungal drugs prevent topical or invasive fungal infections (mycoses) either by stopping growth of fungi (termed fungistatic) or by killing the fungal cells (termed fungicidal).
Chowdhury Mobaswar Hossain +6 more
doaj +1 more source
Linking Cellular Morphogenesis with Antifungal Treatment and Susceptibility in Candida Pathogens
Journal of Fungi, 2019 Fungal infections are a growing public health concern, and an increasingly important cause of human mortality, with Candida species being amongst the most frequently encountered of these opportunistic fungal pathogens.
Jehoshua Sharma +3 more
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Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Candida auris : An Overview of the Emerging Drug-Resistant Fungal Infection
Infection & Chemotherapy, 2022 Candida auris is an invasive fungal pathogen that has been recognized globally as a serious health threat due to its extensive innate and acquired resistance to antifungal drugs. A growing number of emerging cases of C. auris have been reported with resistance to the standard antifungal treatments including azoles, echinocandins, and polyenes, making ...
Adekunle Sanyaolu +8 more
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Advances in Sustainable and Wearable Textile Based Soft Robotics
Advanced Functional Materials, EarlyView.This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas +6 more
wiley +1 more source
mSphere of Influence: Rapid evolution of pathogenesis and drug resistance in human pathogenic fungi
mSpherePengjie Hu works in the field of fungal pathogenesis, drug resistance, and evolution. In this mSphere of Influence article, he reflects on how three works, “Transposon mobilization in the human fungal pathogen Cryptococcus is mutagenic during infection ...
Pengjie Hu
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Nitroheterocyclic drug resistance mechanisms in Trypanosoma brucei [PDF]
, 2016 Objectives The objective of this study was to identify the mechanisms of resistance to nifurtimox and fexinidazole in African trypanosomes. Methods Bloodstream-form Trypanosoma brucei were selected for resistance to nifurtimox and fexinidazole by ...
Kelner, Anna +5 more
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Candidemia : evolution of drug resistance and novel therapeutic approaches [PDF]
, 2021 Candidemia and invasive candidiasis are the most common healthcare-associated invasive fungal infections, with a crude mortality rate of 25-50%. Candida albicans remains the most frequent etiology, followed by C. glabrata, C.
Prigitano, Anna +9 more
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Prevalence of Fungal Drug Resistance in COVID-19 Infection: a Global Meta-analysis
Current Fungal Infection Reports, 2022 Secondary bacterial or fungal infections are one of the most important medical complications among patients with Coronavirus Disease 2019 (COVID-19). The emergence of multidrug-resistant (MDR) candida can cause many problems such as treatment failure, adverse clinical outcomes, and even disease outbreaks.
Habibzadeh, Adrina +9 more
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