Results 11 to 20 of about 4,366,481 (288)
Fungal Biofilms and Drug Resistance
Emerging Infectious Diseases, 2004 Candida species, including the novel opportunistic pathogen Candida dubliniensis, are now emerging as major agents of nosocomial infections. Many such manifestations of infections associated with the formation of Candida biofilms include those occurring ...
Mary Ann Jabra-Rizk +2 more
doaj +5 more sources
Hsp90 governs dispersion and drug resistance of fungal biofilms. [PDF]
PLoS Pathogens, 2011 Fungal biofilms are a major cause of human mortality and are recalcitrant to most treatments due to intrinsic drug resistance. These complex communities of multiple cell types form on indwelling medical devices and their eradication often requires ...
Nicole Robbins +7 more
doaj +7 more sources
Fungal Biofilms, Drug Resistance, and Recurrent Infection. [PDF]
Cold Spring Harbor Perspectives in Medicine, 2018 A biofilm is a surface-associated microbial community. Diverse fungi are capable of biofilm growth. The significance of this growth form for infection biology is that biofilm formation on implanted devices is a major cause of recurrent infection ...
Aaron Mitchell (3881287) +2 more
core +3 more sources
Microbial Cell, 2016 Human fungal infections are increasing in prevalence and acquisition of antifungal drug resistance, while our antifungal drug armamentarium remains very limited, constituting a significant public health problem. Despite the fact that prominent antifungal
Erika Shor +3 more
doaj +2 more sources
Fungal Cell Wall: Emerging Antifungals and Drug Resistance [PDF]
Frontiers in Microbiology, 2019 The cell wall is an essential component in fungal homeostasis. The lack of a covering wall in human cells makes this component an attractive target for antifungal development. The host environment and antifungal stress can lead to cell wall modifications
Soraia L. Lima +2 more
doaj +3 more sources
Virulence Regulation and Drug-Resistance Mechanism of Fungal Infection
Microorganisms, 2022 In this issue, I propose promising developments in the field of the mechanism of virulence factors that can be linked to antifungal resistance [...]
Letizia Angiolella
doaj +3 more sources
Lysine Deacetylases Hda1 and Rpd3 Regulate Hsp90 Function thereby Governing Fungal Drug Resistance
Cell Reports, 2012 The molecular chaperone Hsp90 is a hub of protein homeostasis and regulatory circuitry. Hsp90 function is regulated by posttranslational modifications including acetylation in mammals; however, whether this regulation is conserved remains unknown.
Nicole Robbins +2 more
doaj +2 more sources
Deciphering the role of mitochondria in human fungal drug resistance
MycologyAs pathogenic fungi increasingly threaten public health, particularly in immunocompromised populations, understanding the mechanisms behind fungal drug resistance has become critical.
Yuanyuan Ma +5 more
doaj +4 more sources
Drug resistance mechanisms of fungal biofilms
, 2011 Fungi are ubiquitous in nature and exist in soil, water, plants, and in animals and humans. Similar to bacteria, fungi also form confluent biofilms either singly (mono-species) or with other microbial species (mixed-species). Fungal biofilms are known to
Samaranayake, LP, Seneviratne, CJ
core +2 more sources
Potential Strategies to Control the Risk of Antifungal Resistance in Humans: A Comprehensive Review
Antibiotics, 2023 Fungal infections are becoming one of the main causes of morbidity and mortality in people with weakened immune systems. Mycoses are becoming more common, despite greater knowledge and better treatment methods, due to the regular emergence of resistance ...
Ali A. Rabaan +19 more
doaj +1 more source