Results 11 to 20 of about 84,689 (291)

Deciphering the role of mitochondria in human fungal drug resistance

Mycology
As pathogenic fungi increasingly threaten public health, particularly in immunocompromised populations, understanding the mechanisms behind fungal drug resistance has become critical.
Yuanyuan Ma, Yachun Zhou, Tianyuan Jia, Zilin Zhuang, Peng Xue, Liang Yang   +5 more
doaj   +5 more sources

Fungal Cell Wall: Emerging Antifungals and Drug Resistance [PDF]

Frontiers in Microbiology, 2019
The cell wall is an essential component in fungal homeostasis. The lack of a covering wall in human cells makes this component an attractive target for antifungal development. The host environment and antifungal stress can lead to cell wall modifications
Soraia L. Lima, Arnaldo L. Colombo, João N. de Almeida Junior   +2 more
doaj   +3 more sources

Virulence Regulation and Drug-Resistance Mechanism of Fungal Infection

Microorganisms, 2022
In this issue, I propose promising developments in the field of the mechanism of virulence factors that can be linked to antifungal resistance [...]
Letizia Angiolella
doaj   +3 more sources

Fungal Biofilms, Drug Resistance, and Recurrent Infection. [PDF]

Cold Spring Harbor Perspectives in Medicine, 2018
A biofilm is a surface-associated microbial community. Diverse fungi are capable of biofilm growth. The significance of this growth form for infection biology is that biofilm formation on implanted devices is a major cause of recurrent infection ...
Aaron Mitchell (3881287), Jigar V Desai (5063276), David R. Andes (146260)   +2 more
core   +3 more sources

Carrier-Mediated Drug Uptake in Fungal Pathogens

Genes, 2020
Candida, Aspergillus, and Cryptococcus species are the most frequent cause of severe human fungal infections. Clinically relevant antifungal drugs are scarce, and their effectiveness are hampered by the ability of fungal cells to develop drug resistance ...
Mónica Galocha, MIGUEL C Teixeira, Galocha Mónica   +2 more
exaly   +2 more sources

Prevalence of Fungal Drug Resistance in COVID-19 Infection: a Global Meta-analysis

Current Fungal Infection Reports, 2022
PURPOSE: Secondary bacterial or fungal infections are one of the most important medical complications among patients with Coronavirus Disease 2019 (COVID-19).
Maryam Akbari, Karimimoghadam, Zeinab, Wang, Kan, Adrina Habibzadeh, Habibzadeh, Adrina, Zeinab Karimimoghadam, Fariba Ahmadizar, Mohammad Hossein Imanieh, Imanieh, Mohammad Hossein, Kamran B. Lankarani, Kashani, Seyyed Mohammad Amin, Akbari, Maryam, Reza Tabrizi, Tabrizi, Reza, Ahmadizar, Fariba, Farjam, Mojtaba, Lankarani, Kamran B., Kan Wang, Mojtaba Farjam, Seyyed Mohammad Amin Kashani   +19 more
core   +4 more sources

Regulatory Circuitry Governing Fungal Development, Drug Resistance, and Disease [PDF]

Microbiology and Molecular Biology Reviews, 2011
SUMMARY Pathogenic fungi have become a leading cause of human mortality due to the increasing frequency of fungal infections in immunocompromised populations and the limited armamentarium of clinically useful antifungal drugs.
Rebecca S. Shapiro, Nicole Robbins, Leah E. Cowen   +2 more
core   +3 more sources

Drug resistance mechanisms of fungal biofilms

, 2011
Fungi are ubiquitous in nature and exist in soil, water, plants, and in animals and humans. Similar to bacteria, fungi also form confluent biofilms either singly (mono-species) or with other microbial species (mixed-species). Fungal biofilms are known to
Samaranayake, LP, Seneviratne, CJ
core   +2 more sources

Antifungal resistance in dermatophytosis: A global health concern

Letters in Animal Biology, 2022
Dermatophytosis is a common dermatological problem in animals as well as humans which is associated with interference in immune function. Unlike the antibacterial resistance which is frequently reported, antifungal resistance is less commonly reported ...
Jubeda Begum, P Das
doaj   +1 more source

The metal chaperone protein MtmA plays important roles in antifungal drug susceptibility in Aspergillus fumigatus

Frontiers in Microbiology, 2022
Drug-resistant fungal infections are emerging as an important clinical problem. In general, antifungal resistance results from increased target expression or mutations within the target protein sequence.
Pengfei Zhai, Yinyan Ma, Wenlong Du, Ling Lu   +3 more
doaj   +1 more source