Results 261 to 270 of about 84,689 (291)
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Pathogenesis of Fungal Infections and Drug-Resistance Phenomenon
2020Fungi the primitive eukaryotes are emerging as life-threatening pathogens of public health. Over a decade and ago, the frequency of fungal infections has been enormous, with an increased range of mortality and morbidity in immunocompromised patients.
Sudhakar Pola +3 more
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Human Fungal Pathogens and Drug Resistance Against Azole Drugs
2017Pathogenic fungi causing severe infections in humans with immunocompromised immune system have been the major reasons of deaths in the world. Candida albicans, Cryptococcus neoformans, and Aspergillus fumigatus are among the most prevalent human fungal pathogens. The most widely used therapy used for the invasive fungal infections is the treatment with
Preetida J. Bhetariya +5 more
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Drug development challenges and strategies to address emerging and resistant fungal pathogens
Expert Review of Anti-infective Therapy, 2017Invasive fungal infections represent an expanding threat to public health. The recent emergence of Candida auris, which is often resistant to existing antifungal agents and is associated with a high mortality rate, underscores the urgent need for novel drug development strategies.
Matthew W, McCarthy, Thomas J, Walsh
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In the Crossroad Between Drug Resistance and Virulence in Fungal Pathogens
2018Fungal species from the Cryptococcus, Candida, and Aspergillus genera are recognized as important human pathogens, causing infections which are often deadly and extremely difficult to treat due to their ability to exhibit and develop antifungal resistance and virulence.
Mafalda Cavalheiro +1 more
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Resistance and tolerance mechanisms to antifungal drugs in fungal pathogens
Mycologist, 2003Fungal pathogens are using several mechanisms to circumvent the inhibitory actions of antifungal drugs. The variety of these mechanisms was revealed in recent years by several laboratories with molecular approaches. Besides the identification of genes involved in antifungal drug resistance and the discovery of alternative pathways of resistance (i.e ...
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The race to beat deadly, drug-resistant fungal diseases
Open Access GovernmentThe race to beat deadly, drug-resistant fungal diseases Professors Elaine Bignell and Neil A.R. Gow address the growing threat of fungal infections, highlighting the sharp rise in drug-resistant cases, and the required efforts to better understand and mitigate fAMR. Fungi are agents of mass crop destruction, but
Elaine Bignell, Neil A R Gow
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Fungal Resistance to Antimycotic Drugs
International Journal of Dermatology, 1991openaire +2 more sources
- Molecular Characterization of Fungal Drug Resistance
2011Maurizio Sanguinetti +2 more
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Antifungal Drug Development: Targeting the Fungal Sphingolipid Pathway
Journal of Fungi (Basel, Switzerland), 2020Kyle Mcevoy +2 more
exaly