Results 271 to 280 of about 543,044 (334)

Multidirectional in silico and in vitro Research for the Pharmaceutical Potential of Fibigia Clypeata (L.) Medik: Phytochemical, Antimicrobial, and Antimyeloma Properties

ChemistryOpen, EarlyView.
Fibigia clypeata water extract has a slightly more substantial inhibitory effect than the methanol extract. F. clypeata decreased cell viability in three human MM cells and the MCF10A cell lines. Cyanidin 3‐rutinoside chloride has the highest binding affinity to Staphylococcus aureus MurB, Candida parapsilosis, and Candida albicans dihydrofolate ...
Tuba Unver, Ugur Uzuner, Dilara Akcora‐Yildiz, Ismet Gurhan, Caglar Arkan, Zeynep Ozdemir   +5 more
wiley   +1 more source

Proteomic Analysis Revealed that DVL, a Lectin Purified from <i>Dioclea violacea</i> Seeds, Induced a Change in the Protein Profile of <i>Candida albicans</i>. [PDF]

ACS Omega
Silva RRS, Santos MHC, Santos ALE, Freitas CDT, Carneiro RF, Nagano CS, Mesquita FP, Souza PFN, Teixeira CS.   +8 more
europepmc   +1 more source

Essential Oil Profiles of Lippia turbinata (Verbenaceae) from Argentina: Insights from a Systematic Review and Meta‐Analysis

ChemistryOpen, EarlyView.
This study systematically reviews essential oil (EO) profiles of Lippia turbinata (Verbenaceae) populations from Argentina. A meta‐analysis reveals significant chemical variability and distinct chemotypes, primarily defined by limonene, carvone, β‐caryophyllene, and caryophyllene oxide.
Fernando Livio Corzo, Franco Emmanuel Calvo, Emilio Fernando Lizarraga, Guillermo Emilio Marcial, Maria Ines Mercado   +4 more
wiley   +1 more source

Targeted loss of heterozygosity in Candida albicans using CRISPR-Cas9 reveals the functional impact of allelic variation. [PDF]

Genetics
Després PC, Gervais NC, Fogal M, Rogers RKJ, Cuomo CA, Shapiro RS.   +5 more
europepmc   +1 more source

Arenaria serpyllifolia as a Natural Antiviolaceum Agent: Phytochemical, Biological, and Molecular Approaches

ChemistryOpen, EarlyView.
Arenaria serpyllifolia extract exhibits strong antioxidant, antimicrobial, antibiofilm, and antiquorum sensing activities. Key compounds, including levoglucosan and guanosine, show potent CviR receptor binding. Violacein inhibition and molecular dynamics confirm their stability, highlighting their potential as quorum sensing inhibitors and therapeutic ...
Meryem Burcu Külahcı, Betül Aydın, Emine Incilay Torunoğlu, Zekeriya Düzgün, Alper Durmaz, Erdi Can Aytar   +5 more
wiley   +1 more source

Aspergillosis: A comprehensive review of pathogenesis, drug resistance, and emerging therapeutics. [PDF]

J Food Drug Anal
Singh A, Singh J, Kumar S.
europepmc   +1 more source

Crystal Structure–Activity Relationship of Some MeO Phenylacrylonitriles: Dual Antimicrobial–Cytotoxic Effects and in Silico Perspectives

ChemistryOpen, EarlyView.
Methoxy‐phenylacrylonitriles (2a–c) are synthesized and characterized by fourier‐transform infrared spectroscopy, nuclear magnetic resonance spectroscopy, and X‐ray crystallography (for 2a,b). Compound 2b shows selective cytotoxicity against MCF‐7 cells (IC50: 34 μM) and enhances activity against Gram‐positive bacteria. Molecular docking reveals strong
Leyla Babali Özen, Öner Ekici, Furkan Özen, Süleyman Berberler, Gül Özkan, Betül Yılmaz Öztürk, Pınar Oztopcu‐Vatan, Cansu Filik İşçen, Günseli Turgut Cin   +8 more
wiley   +1 more source

Next-generation antifungal drugs: Mechanisms, efficacy, and clinical prospects. [PDF]

Acta Pharm Sin B
Lu X, Zhou J, Ming Y, Wang Y, He R, Li Y, Feng L, Zeng B, Du Y, Wang C.   +9 more
europepmc   +1 more source

Leveraging synthetic genetic array screening to identify therapeutic targets and inhibitors for combatting azole resistance in <i>Candida glabrata</i>. [PDF]

Microbiol Spectr
Williams CC, Usher J.
europepmc   +1 more source

Genetic analysis of common triazole resistance mechanisms in a collection of <i>Aspergillus lentulus</i> clinical isolates from the United States. [PDF]

Antimicrob Agents Chemother
Martin-Vicente A, Nywening AV, Xie J, Thorn HI, Guruceaga X, Fortwendel JR.   +5 more
europepmc   +1 more source