Results 51 to 60 of about 543,044 (334)
Drug Resistance and Evolvability in an Emerging Human Fungal Pathogen
mBio, 2022 Over the past decade, Candida auris has emerged as a highly transmissible human fungal pathogen. Because of its ability to transmit between patients in hospitals and its ability to rapidly develop drug resistance, C. auris presents unique challenges.
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Microbial Cell, 2016 Human fungal infections are increasing in prevalence and acquisition of antifungal drug resistance, while our antifungal drug armamentarium remains very limited, constituting a significant public health problem. Despite the fact that prominent antifungal
Erika Shor +3 more
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PLoS Genetics, 2019 Drug resistance is a rapidly emerging concern, thus prompting the development of novel therapeutics or combinatorial therapy. Currently, combinatorial therapy targets are based on knowledge of drug mode of action and/or resistance mechanisms ...
J. Usher, K. Haynes
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The mPEG-PCL Copolymer for Selective Fermentation of Staphylococcus lugdunensis Against Candida parapsilosis in the Human Microbiome. [PDF]
, 2016 Many human skin diseases, such as seborrheic dermatitis, potentially occur due to the over-growth of fungi. It remains a challenge to develop fungicides with a lower risk of generating resistant fungi and non-specifically killing commensal microbes.
Barshop, Bruce A +15 more
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In vitro susceptibility of Cuban Aspergillus spp. strains of clinical and environmental origin
Biomédica: revista del Instituto Nacional de Salud, 2017 Introduction: The behavior of antifungal susceptibility of Aspergillus spp. in Cuba remains unknown. The antifungals recommended to treat aspergillosis are amphotericin B, itraconazole, voriconazole and echinocandins. The influence of the environment may
Javier L. San Juan +6 more
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Nature Communications, 2016 The fungal pathogen Candida glabrata has emerged as a major health threat since it readily acquires resistance to multiple drug classes, including triazoles and/or echinocandins.
K. Healey +12 more
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Linking Cellular Morphogenesis with Antifungal Treatment and Susceptibility in Candida Pathogens
Journal of Fungi, 2019 Fungal infections are a growing public health concern, and an increasingly important cause of human mortality, with Candida species being amongst the most frequently encountered of these opportunistic fungal pathogens.
Jehoshua Sharma +3 more
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Virulence, 2017 Increases in the incidence and mortality due to the major invasive fungal infections such as aspergillosis, candidiasis and cryptococcosis caused by the species of Aspergillus, Candida and Cryptococcus, are a growing threat to the immunosuppressed ...
P. R. Juvvadi +3 more
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Biomédica: revista del Instituto Nacional de Salud, 2023 Introduction. Malassezia is a lipophilic and lipid-dependent yeast genus belonging to the skin microbiota of humans and other animals. However, due to dysbiosis processes or other factors in the host, this yeast can cause different pathologies, ranging ...
Kevin Ehemann +2 more
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Controlling Drug Resistance in Fungal Systems by Zinc Cluster Proteins [PDF]
Biophysical Journal, 2013 Drug resistance is a serious complication for patients with an infection, and unfortunately, bacteria and fungi are quickly rendering many therapeutic drugs ineffective. In Saccharomyces cerevisiae, this mechanism is defined as pleiotropic drug-resistance (PDR).
Heather W. Pinkett, Kari J. Tanaka
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