Results 51 to 60 of about 160,880 (298)

Expression of ERG11, ERG3, MDR1 and CDR1 genes in Candida tropicalis

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2023
Introduction. Drug resistance to azoles is a growing problem in the Candida genus. Objective. To analyze molecularly the genes responsible for fluconazole resistance in Candida tropicalis strains. Materials and methods. Nineteen strains, with and without
Ana Elisa Rojas   +3 more
doaj   +1 more source

The Fungal Cell Wall : Structure, Biosynthesis, and Function [PDF]

open access: yes, 2017
N.G. is funded by the Wellcome Trust via a senior investigator award and a strategic award and by the MRC Centre for Medical Mycology. C.M. acknowledges the support of the Wellcome Trust and the MRC. N.G. and C.M.
Aimanianda   +215 more
core   +1 more source

Cryptococcus flips its lid – membrane phospholipid asymmetry modulates antifungal drug resistance and virulence

open access: yesMicrobial Cell, 2016
Human fungal infections are increasing in prevalence and acquisition of antifungal drug resistance, while our antifungal drug armamentarium remains very limited, constituting a significant public health problem. Despite the fact that prominent antifungal
Erika Shor   +3 more
doaj   +1 more source

Screening of the central nervous system in children with invasive pulmonary aspergillosis [PDF]

open access: yes, 2014
Peer reviewedPublisher ...
Broenen, Emmi   +5 more
core   +2 more sources

The Infectious Disease Ontology in the Age of COVID-19 [PDF]

open access: yes, 2021
The Infectious Disease Ontology (IDO) is a suite of interoperable ontology modules that aims to provide coverage of all aspects of the infectious disease domain, including biomedical research, clinical care, and public health.
Babcock, Shane   +3 more
core   +1 more source

Linking Cellular Morphogenesis with Antifungal Treatment and Susceptibility in Candida Pathogens

open access: yesJournal of Fungi, 2019
Fungal infections are a growing public health concern, and an increasingly important cause of human mortality, with Candida species being amongst the most frequently encountered of these opportunistic fungal pathogens.
Jehoshua Sharma   +3 more
doaj   +1 more source

New Clox Systems for rapid and efficient gene disruption in Candida albicans [PDF]

open access: yes, 2014
Acknowledgements: We are grateful to Janet Quinn, Lila Kastora, Joanna Potrykus, Michelle Leach, and others for sharing their experiences with the Clox cassettes.
Ballou, Elizabeth R   +6 more
core   +4 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

mSphere of Influence: Rapid evolution of pathogenesis and drug resistance in human pathogenic fungi

open access: yesmSphere
Pengjie Hu works in the field of fungal pathogenesis, drug resistance, and evolution. In this mSphere of Influence article, he reflects on how three works, “Transposon mobilization in the human fungal pathogen Cryptococcus is mutagenic during infection ...
Pengjie Hu
doaj   +1 more source

Stress, Drugs, and Evolution: the Role of Cellular Signaling in Fungal Drug Resistance [PDF]

open access: yesEukaryotic Cell, 2008
The survival of all organisms depends critically upon interactions with the environment, mediated largely through the action of small molecules. Small molecules can provide the nutrients to support life ([195][1]), mediate communication between organisms ([25][2], [76][3], [238][4]), or ...
Leah E, Cowen, William J, Steinbach
openaire   +2 more sources

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