Results 51 to 60 of about 613,359 (339)

Expression of ERG11, ERG3, MDR1 and CDR1 genes in Candida tropicalis

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2023
Introduction. Drug resistance to azoles is a growing problem in the Candida genus. Objective. To analyze molecularly the genes responsible for fluconazole resistance in Candida tropicalis strains. Materials and methods. Nineteen strains, with and without
Ana Elisa Rojas   +3 more
doaj   +1 more source

The Fungal Cell Wall : Structure, Biosynthesis, and Function [PDF]

open access: yes, 2017
N.G. is funded by the Wellcome Trust via a senior investigator award and a strategic award and by the MRC Centre for Medical Mycology. C.M. acknowledges the support of the Wellcome Trust and the MRC. N.G. and C.M.
Aimanianda   +215 more
core   +1 more source

Calcineurin in fungal virulence and drug resistance: Prospects for harnessing targeted inhibition of calcineurin for an antifungal therapeutic approach

open access: yesVirulence, 2017
Increases in the incidence and mortality due to the major invasive fungal infections such as aspergillosis, candidiasis and cryptococcosis caused by the species of Aspergillus, Candida and Cryptococcus, are a growing threat to the immunosuppressed ...
P. R. Juvvadi   +3 more
semanticscholar   +1 more source

Regulatory Circuitry Governing Fungal Development, Drug Resistance, and Disease [PDF]

open access: yesMicrobiology and Molecular Biology Reviews, 2011
SUMMARYPathogenic fungi have become a leading cause of human mortality due to the increasing frequency of fungal infections in immunocompromised populations and the limited armamentarium of clinically useful antifungal drugs.Candida albicans,Cryptococcus neoformans, andAspergillus fumigatusare the leading causes of opportunistic fungal infections.
Rebecca S, Shapiro   +2 more
openaire   +2 more sources

The Quiet and Underappreciated Rise of Drug-Resistant Invasive Fungal Pathogens [PDF]

open access: yesJournal of Fungi, 2020
Human fungal pathogens are attributable to a significant economic burden and mortality worldwide. Antifungal treatments, although limited in number, play a pivotal role in decreasing mortality and morbidities posed by invasive fungal infections (IFIs). However, the recent emergence of multidrug-resistant Candida auris and Candida glabrata and acquiring
Amir Arastehfar   +7 more
openaire   +5 more sources

Screening of the central nervous system in children with invasive pulmonary aspergillosis [PDF]

open access: yes, 2014
Peer reviewedPublisher ...
Broenen, Emmi   +5 more
core   +2 more sources

In vitro susceptibility of Cuban Aspergillus spp. strains of clinical and environmental origin

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2017
Introduction: The behavior of antifungal susceptibility of Aspergillus spp. in Cuba remains unknown. The antifungals recommended to treat aspergillosis are amphotericin B, itraconazole, voriconazole and echinocandins. The influence of the environment may
Javier L. San Juan   +6 more
doaj   +1 more source

Kajian Molekuler Resistensi Candida Albicans Terhadap Antifungi [PDF]

open access: yes, 2014
Candida albicans is one of the species Candida which mostly cause infection in human. Antifungal agent azole, polyene, echinocandin, and flucytosine are commonly used for Candida albicans infection treatment.
Candrasari, D. S. (Damiana)
core   +3 more sources

Finding the needle in a haystack: Mapping antifungal drug resistance in fungal pathogen by genomic approaches

open access: yesPLoS Pathogens, 2019
Fungi are ubiquitous on earth and are essential for the maintenance of the global ecological equilibrium. Despite providing benefits to living organisms, they can also target specific hosts and inflict damage.
D. Sanglard
semanticscholar   +1 more source

Drug Resistance and Novel Therapeutic Approaches in Invasive Candidiasis

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Candida species are the leading cause of invasive fungal infections worldwide and are associated with acute mortality rates of ~50%. Mortality rates are further augmented in the context of host immunosuppression and infection with drug-resistant Candida ...
Sarah E. Murphy, T. Bicanic
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy