Results 61 to 70 of about 5,954,250 (317)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Graft‐versus‐host disease (GvHD) remains one of the most significant complications of hematopoietic stem cell transplantation (HSCT). Abatacept, a selective T‐cell costimulation modulator, is a relatively novel prophylactic agent, though pediatric data remain limited.
Matthijs D. Kruizinga +3 more
wiley +1 more source
Nano-Drug Delivery Systems in Oral Cancer Therapy: Recent Developments and Prospective
, 2023 Oral cancer (OC), characterized by malignant tumors in the mouth, is one of the most prevalent malignancies worldwide. Chemotherapy is a commonly used treatment for OC; however, it often leads to severe side effects on human bodies.
Zhiyong Li +9 more
core +1 more source
Calculation of reference intervals using an indirect approach from laboratory database
Advances in Laboratory MedicineThe establishment of reference intervals (RIs) for biochemical parameters is crucial for the accurate interpretation of laboratory test results and clinical decision-making. This study aims to evaluate the feasibility of determining RIs using an indirect
Martin-Riera Victor +13 more
doaj +1 more source
Frontiers in MicrobiologyMycobacterium tuberculosis (Mtb) is the pathogenic agent of tuberculosis (TB). Intracellular survival plays a central role in the pathogenesis of Mtb in a manner that is dependent on an array of transcriptional regulators for Mtb.
Hui Wang +8 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine +21 more
wiley +1 more source
Evaluation of the Peer Support Program (Student Drug Prevention) 1986-1987
, 2019 The Peer Support program is a school based program funded by the National Campaign Against Drug Abuse (NCADA) as a drug prevention strategy. Prior to the existence of the NCADA the program was funded through the NSW Drug and Alcohol Authority.
Directorate of the Drug Offensive
core +1 more source
Cost-effectiveness of tenofovir instead of zidovudine for use in first-line antiretroviral therapy in settings without virological monitoring. [PDF]
, 2012 BACKGROUND: The most recent World Health Organization (WHO) antiretroviral treatment guidelines recommend the inclusion of zidovudine (ZDV) or tenofovir (TDF) in first-line therapy.
Alec Miners +31 more
core +2 more sources
Non-surgical osteoarthritis therapy, intra-articular drug delivery towards clinical applications [PDF]
, 2020 Osteoarthritis (OA）is a common orthopaedic disease in middle-aged and aged people. To date, no disease-modifying drug is available to prevent the progression of OA.
Liang, Yujie +13 more
core +1 more source
The LEDGIN GS-9822 inhibits HIV-2 infection and enhances HIV-2 latency
Microbiology SpectrumHIV integration is targeted toward active transcription units through the interaction of HIV integrase with the cellular co-factor LEDGF/p75. LEDGINs, small molecule inhibitors of this interaction, reduce HIV-1 integration and retarget residual ...
Anne Bruggemans +5 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak +9 more
wiley +1 more source