Results 71 to 80 of about 2,964,728 (312)

Remodeling Collagen Microenvironment in Liver Using a Biomimetic Nano‐Regulator for Reversal of Liver Fibrosis

Advanced Science, 2023
Liver fibrosis is a progressive histological manifestation that happens in almost all chronic liver diseases. An unabated liver fibrosis may eventually develop into liver cirrhosis or hepatocellular carcinoma.
Yan Liang, Jinjin Wang, Chenlu Xu, Wenshuai Han, Sixuan Wu, Yonghua Wu, Jingge Zhang, Junjie Liu, Zhenzhong Zhang, Jinjin Shi, Kaixiang Zhang   +10 more
doaj   +1 more source

Cognitive behavioral group therapy versus psychoeducational intervention in Parkinson's disease [PDF]

, 2018
Objective: The aim of the current study was to evaluate whether cognitive behavioral group therapy has a positive impact on psychiatric, and motor and non-motor symptoms in Parkinson’s disease (PD).
Berardelli, Isabella, Bloise, Maria Carmela, Bologna, Matteo, Conte, Antonella, Fabbrini, Giovanni, Lamis, Dorian A., Pasquini, Massimo, Pompili, Maurizio   +7 more
core   +2 more sources

Exploring the Impact of Telerehabilitation on Physical Performance in Patients with Pulmonary Fibrosis

Telemedicine Reports
Background: Interstitial lung disease (ILD) is a heterogeneous group of lung parenchymal diseases. Idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP) are typical idiopathic interstitial pneumonias associated with ...
Matti Okker, Kirsi Lindgren, Herkko Ryynänen, Marjukka Myllärniemi, Mari Ainola, Maria Hollmen   +5 more
doaj   +1 more source

Epigallocatechin-3-gallate ameliorates glucolipid metabolism and oxidative stress in type 2 diabetic rats

Diabetes & Vascular Disease Research, 2020
Aims: The objective of this study was to explore the effects of epigallocatechin-3-gallate (EGCG) on type 2 diabetes mellitus (T2DM). Main methods: Male Sprague–Dawley rats were allocated into six groups.
Wenru Li, Chaonan Zhu, Tianheng Liu, Weifang Zhang, Xu Liu, Peng Li, Tiantian Zhu   +6 more
doaj   +1 more source

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song, Jonathan Baron, Carlos Chavez Perez, Sidharth Ramesh, Jane Minturn, Kavita A. Desai, Amish C. Shah, Jean M. Belasco, Kristina A. Cole, Michael J. Fisher, Phillip B. Storm, Peter M. Madsen, Goldie Kurtz, Robert A. Lustig, Christine Hill‐Kayser, Michael J. LaRiviere   +15 more
wiley   +1 more source

The role of transcriptional regulators in metal ion homeostasis of Mycobacterium tuberculosis

Frontiers in Cellular and Infection Microbiology
Metal ions are essential trace elements for all living organisms and play critical catalytic, structural, and allosteric roles in many enzymes and transcription factors.
Shuxian Wang, Ren Fang, Hui Wang, Xiaotian Li, Jiayin Xing, Zhaoli Li, Ningning Song   +6 more
doaj   +1 more source

KLK3/PSA and cathepsin D activate VEGF-C and VEGF-D

eLife, 2019
Vascular endothelial growth factor-C (VEGF-C) acts primarily on endothelial cells, but also on non-vascular targets, for example in the CNS and immune system.
Sawan Kumar Jha, Khushbu Rauniyar, Ewa Chronowska, Kenny Mattonet, Eunice Wairimu Maina, Hannu Koistinen, Ulf-Håkan Stenman, Kari Alitalo, Michael Jeltsch   +8 more
doaj   +1 more source

Capillary Rarefaction in Obesity and Metabolic Diseases—Organ-Specificity and Possible Mechanisms

Cells, 2020
Obesity and its comorbidities like diabetes, hypertension and other cardiovascular disorders are the leading causes of death and disability worldwide.
Satu Paavonsalo, Sangeetha Hariharan, Madeleine H. Lackman, Sinem Karaman   +3 more
doaj   +1 more source

Era of direct acting anti-viral agents for the treatment of hepatitis C. [PDF]

, 2018
Hepatitis C infection is universal and the most common indication of liver transplantation in the United States. The period of less effective interferon therapy with intolerable side effects has gone.
Ahmed, Monjur
core   +1 more source

Ethnic Differences in the Association Between SOD2 rs4880 and Hepatotoxicity in Pediatric Acute Lymphoblastic Leukemia: A Report From the REDIAL Consortium

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Treatment‐associated hepatotoxicity (TAH) is a common complication of pediatric acute lymphoblastic leukemia (ALL) treatment, but genetic risk factors remain poorly understood. We evaluated the SOD2 rs4880 variant in 544 children with ALL at Texas Children's Hospital. After adjusting for demographic and clinical covariates, the rs4880 C allele
Emily J. Mason, John P. Woodhouse, Joanna S. Yi, M. Monica Gramatges, Olga A. Taylor, Veronica A. Morales, Shalini Dhamodharan, Marley Roberts, Karen R. Rabin, Philip J. Lupo, Michael E. Scheurer, Van Huynh, Steven D. Mittelman, Etan Orgel, Austin L. Brown   +14 more
wiley   +1 more source