Results 21 to 30 of about 158,142 (288)
Glutamine transporters as pharmacological targets: From function to drug design
Asian Journal of Pharmaceutical Sciences, 2020 Among the different targets of administered drugs, there are membrane transporters that play also a role in drug delivery and disposition. Moreover, drug-transporter interactions are responsible for off-target effects of drugs underlying their toxicity ...
Mariafrancesca Scalise +4 more
doaj +3 more sources
, 2018 Fil: Talevi, Alan. Universidad Nacional de La Plata. Facultad de Ciencas Exactas. Laboratorio de Investigación y Desarrollo de Bioactivos; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Ciencias Biológicas. Cátedra de Química Medicinal; Argentina.
Talevi, Alan +2 more
openaire +3 more sources
Prenatal opioid exposure significantly impacts placental protein kinase C (PKC) and drug transporters, leading to drug resistance and neonatal opioid withdrawal syndrome [PDF]
Frontiers in NeuroscienceBackgroundNeonatal Opioid Withdrawal Syndrome (NOWS) is a consequence of in-utero exposure to prenatal maternal opioids, resulting in the manifestation of symptoms like irritability, feeding problems, tremors, and withdrawal signs.
Uppala Radhakrishna +8 more
doaj +2 more sources
Food Additives Inhibit Intestinal Drug Transporters but Have Limited Effect on In Vitro Drug Permeability. [PDF]
Mol PharmFood additives are chemical substances that are added to processed food to improve its flavor, texture, or appearance. Food additives can inhibit intestinal transporters, such as breast cancer resistance protein (BCRP), multidrug resistance associated ...
Suominen L +3 more
europepmc +2 more sources
Editorial: Diverse functions of drug transporters [PDF]
Frontiers in PharmacologyJeffry C. Granados +2 more
doaj +2 more sources
Overview of Drug Transporters in Human Placenta [PDF]
International Journal of Molecular Sciences, 2021 Michiko Yamashita +2 more
exaly +2 more sources
Physiology, Biochemistry, and Pharmacology of Transporters for Organic Cations [PDF]
, 2021 Membrane transporters are of vital importance for cells. They mediate the flux of many substances through the plasma membrane. In this book, the transporters for organic cations, a special class of membrane transporters, are presented.
core +1 more source
Frontiers in Pharmacology, 2021 The kidneys are a pair of important organs that excretes endogenous waste and exogenous biological agents from the body. Numerous transporters are involved in the excretion process.
Wei Zou +9 more
doaj +1 more source
Drug transporters in pharmacokinetics [PDF]
Naunyn-Schmiedeberg's Archives of Pharmacology, 2006 This review deals with the drug transporters allowing drugs to enter and leave cells by carrier-mediated pathways. Emphasis is put on liver transporters but systems in gut, kidney, and blood-brain barrier are mentioned as well. Drug-drug interactions on carriers may provoke significant modification in pharmacokinetics as do carrier gene polymorphisms ...
Ernst, Petzinger, Joachim, Geyer
openaire +2 more sources
Imbalance of Drug Transporter-CYP450s Interplay by Diabetes and Its Clinical Significance
Pharmaceutics, 2020 The pharmacokinetics of a drug is dependent upon the coordinate work of influx transporters, enzymes and efflux transporters (i.e., transporter-enzyme interplay). The transporter–enzyme interplay may occur in liver, kidney and intestine.
Yiting Yang, Xiaodong Liu
doaj +1 more source