Results 1 to 10 of about 32,629 (301)

Small hard drusen and associated factors in early seniority.

PLoS ONE, 2022
PurposeThe purpose of this study was to examine the ocular and systemic risk profile of the fundus phenotype ≥ 20 small hard (macular) drusen (< 63 μm in diameter).MethodsThis single-center, cross-sectional study of 176 same-sex twin pairs aged 30 to 80 (
Mohamed Belmouhand, Simon P Rothenbuehler, Sami Dabbah, Jakob Bjerager, Birgit Sander, Jacob B Hjelmborg, Christine Dalgård, Rasmus Jensen, Michael Larsen   +8 more
doaj   +1 more source

The HIT Study—The Hydroxychloroquine Effect in the Treatment of Patients with Age-Related Macular Degeneration: A Randomized Controlled Trial

Medicina, 2023
Background and Objectives: Decreased age-related macular degeneration (AMD) has been reported in individuals with rheumatoid arthritis treated with hydroxychloroquine (HCQ, plaquenil).
Tal Yahalomi, Yoav Pikkel, Roee Arnon, Dafi Porat, Joseph Pikkel   +4 more
doaj   +1 more source

Topographic Distribution and Progression of Soft Drusen Volume in Age-Related Macular Degeneration Implicate Neurobiology of Fovea

Investigative Ophthalmology and Visual Science, 2021
Purpose To refine estimates of macular soft drusen abundance in eyes with age-related macular degeneration (AMD) and evaluate hypotheses about drusen biogenesis, we investigated topographic distribution and growth rates of drusen by optical coherence ...
A. Pollreisz, G. Reiter, H. Bogunović, L. Baumann, Astrid Jakob, F. Schlanitz, S. Sacu, C. Owsley, K. Sloan, C. Curcio, U. Schmidt-Erfurth   +10 more
semanticscholar   +1 more source

Drusen characteristics of type 2 macular neovascularization in age-related macular degeneration

BMC Ophthalmology, 2020
Background Type 2 macular neovascularization (MNV) is supposed to be a rare condition in age-related macular degeneration (AMD). The main purpose of this study was to assess accompanying factors of type 2 MNV in AMD.
Daniel Ahmed, Martin Stattin, Anna-Maria Haas, Alexandra Graf, Katharina Krepler, Siamak Ansari-Shahrezaei   +5 more
doaj   +1 more source

Evaluation of the microperimetry in eyes with cuticular drusen

Scientific Reports, 2022
Retinal sensitivity may vary by subtypes of cuticular drusen. This retrospective study included 52 eyes of 32 patients with cuticular drusen. All the patients underwent assessment of best-corrected visual acuity (BCVA), spectral-domain optical coherence ...
Seung Wan Nam, Jung Hwa Lee, Zeeyoon Byun, Don-Il Ham, Mingui Kong   +4 more
doaj   +1 more source

Validation of a Novel Automated Algorithm to Measure Drusen Volume and Area Using Swept Source Optical Coherence Tomography Angiography

Translational Vision Science & Technology, 2021
Purpose The purpose of this study was to validate a novel automated swept source optical coherence tomography angiography (SS-OCTA) algorithm to measure elevations of the retinal pigment epithelium (RPE) in eyes with nonexudative age-related macular ...
Xiaoshuang Jiang, Mengxi Shen, Liang Wang, L. de Sisternes, M. Durbin, W. Feuer, P. Rosenfeld, Giovanni Gregori   +7 more
semanticscholar   +1 more source

Population-Based Prevalence and 5-Year Change of Soft Drusen, Pseudodrusen, and Pachydrusen in a Japanese Population

Ophthalmology Science, 2021
Purpose: To elucidate the prevalence of soft drusen, pseudodrusen, and pachydrusen and their 5-year changes in a Japanese population. Design: Longitudinal population-based cohort study conducted from 2013 through 2017. Participants: Residents 40 years of
Miki Sato-Akushichi, MD, Reiko Kinouchi, MD, PhD, Satoshi Ishiko, MD, PhD, Kazuomi Hanada, MD, PhD, Hiroki Hayashi, Daiki Mikami, Shinji Ono, MD, PhD, Yasuo Yanagi, MD, PhD   +7 more
doaj   +1 more source

OCT Based Interpretation of the Optic Nerve Head Anatomy and Prevalence of Optic Disc Drusen in Patients with Idiopathic Intracranial Hypertension (IIH)

Life, 2021
We aimed to systematically examine the optic nerve head anatomy in patients with idiopathic intracranial hypertension (IIH) using a standardized optical coherence tomography (OCT) protocol.
E. A. Wibroe, L. Malmqvist, S. Hamann
semanticscholar   +1 more source

Drusen and pigment abnormality predict the development of neovascular age-related macular degeneration in Japanese patients

PLoS ONE, 2021
Drusen are known to be the important hallmark to predict the development of age-related macular degeneration (AMD). The prevalence of drusen is lower in Asians compared with Caucasians so that the role of signs constituting early AMD is not well ...
Shoji Notomi, S. Shiose, K. Ishikawa, Yosuke Fukuda, Kumiko Kano, Kenichiro Mori, Iori Wada, Yoshihiro Kaizu, H. Matsumoto, M. Akiyama, K. Sonoda   +10 more
semanticscholar   +1 more source

Integrity of the Hyperreflective Layer in the Inner Choroid in Eyes with Drusen

Ophthalmology and Therapy, 2023
Introduction This study aimed to compare the integrity of the hyperreflective layer of the inner choroid in eyes with and without drusen. Methods Swept-source optical coherence tomography images of patients with drusen and normal controls were reviewed ...
Young Ho Kim, Cheolmin Yun, Jaeryung Oh
doaj   +1 more source