Results 11 to 20 of about 25,200 (252)

Radiomic Characterization and Automated Classification of Drusen Substructure Phenotype Associated with High-Risk Dry Age-Related Macular Degeneration [PDF]

Diagnostics
Background/Objectives: Optical coherence tomography (OCT)-reflective drusen substructures (ODSs) are associated with the conversion of intermediate AMD to geographic atrophy (GA). However, ODSs must be manually identified, a laborious process introducing
Scott W. Perkins, Neal Shah, Jon Whitney, Karen Matar, Hannah J. Yu, Charles C. Wykoff, Justis P. Ehlers   +6 more
doaj   +2 more sources

Integrative analysis of the choroid by quantifying Haller vessel and choriocapillaris parameters in different drusen subtypes [PDF]

Scientific Reports, 2021
This study aimed to quantify the Haller vessel and choriocapillaris (CC) parameters in drusen subtypes in nonexudative age-related macular degeneration (AMD) and pachydrusen.
Hyungwoo Lee, Seungmin Kim, Myung Ae Kim, Young Joon Jo, Woo Hyuk Lee, Hyung Chan Kim, Hyewon Chung   +6 more
doaj   +2 more sources

Age-related macular degeneration, subretinal drusenoid deposits, and cuticular and calcified drusen in black and hispanic subjects [PDF]

International Journal of Retina and Vitreous
Background Subretinal drusenoid deposits (SDDs), cuticular drusen, and calcified drusen have been linked to rapid progression of age-related macular degeneration (AMD). SDDs have also been linked to high-risk vascular diseases (HRVDs).
John M. Tan, Yang Fei, Liang Wang, Oscar Otero-Marquez, Tasin R. Bhuiyan, J. Fernando Arevalo, Gareth M.C. Lema, Roland Theodore Smith   +7 more
doaj   +2 more sources

Retinal Angiomatous Proliferation in an Eye with Cuticular Drusen [PDF]

Case Reports in Ophthalmology, 2015
Purpose: To report the presence of retinal angiomatous proliferation (RAP) in an eye with cuticular drusen detected by fluorescein and indocyanine green angiography by confocal scanning laser ophthalmoscopy and by spectral-domain optical coherence ...
Atsuko Sato, Nami Senda, Emi Fukui, Kouichi Ohta   +3 more
doaj   +2 more sources

Drusen classification and quantification in pseudophakic postmortem eyes implanted with or without blue-light filtering intraocular lenses

The Pan-American Journal of Ophthalmology
Purpose: To investigate the effect of blue-light filtering intraocular lenses on drusen formation in postmortem eyes via histopathological analysis.
Emmanuel Issa Bassam Nassrallah, Christina Mastromonaco, Emily Marcotte, Emma Youhnovska, Mohamed Abdouh, Miguel N. Burnier   +5 more
doaj   +2 more sources

Retinal peripapillary nerve fiber and retinal ganglion cell layer thickening preceed atrophy in children and teenagers with optic disc drusen. [PDF]

Sci Rep
Rudolph L, Baldassarre V, Halfter K, Lottspeich C, Rudolph G, Priglinger CS.   +5 more
europepmc   +3 more sources

Low-Reflectivity Drusen With Overlying RPE Damage Revealed by Spectral-Domain OCT: Hint for the Development of Age-Related Macular Degeneration

Frontiers in Medicine, 2021
Purpose: To observe the relationship between the characteristic changes in the drusen morphology revealed by the spectral-domain optical coherence tomography (SD-OCT) and the progression of age-related macular degeneration (AMD).Methods: A total of 380 ...
Shasha Yang, Zongyin Gao, Haijiang Qiu, Chengguo Zuo, Lan Mi, Hui Xiao, Xing Liu   +6 more
doaj   +1 more source

The HIT Study—The Hydroxychloroquine Effect in the Treatment of Patients with Age-Related Macular Degeneration: A Randomized Controlled Trial

Medicina, 2023
Background and Objectives: Decreased age-related macular degeneration (AMD) has been reported in individuals with rheumatoid arthritis treated with hydroxychloroquine (HCQ, plaquenil).
Tal Yahalomi, Yoav Pikkel, Roee Arnon, Dafi Porat, Joseph Pikkel   +4 more
doaj   +1 more source

Drusen characteristics of type 2 macular neovascularization in age-related macular degeneration

BMC Ophthalmology, 2020
Background Type 2 macular neovascularization (MNV) is supposed to be a rare condition in age-related macular degeneration (AMD). The main purpose of this study was to assess accompanying factors of type 2 MNV in AMD.
Daniel Ahmed, Martin Stattin, Anna-Maria Haas, Alexandra Graf, Katharina Krepler, Siamak Ansari-Shahrezaei   +5 more
doaj   +1 more source

Small hard drusen and associated factors in early seniority.

PLoS ONE, 2022
PurposeThe purpose of this study was to examine the ocular and systemic risk profile of the fundus phenotype ≥ 20 small hard (macular) drusen (< 63 μm in diameter).MethodsThis single-center, cross-sectional study of 176 same-sex twin pairs aged 30 to 80 (
Mohamed Belmouhand, Simon P Rothenbuehler, Sami Dabbah, Jakob Bjerager, Birgit Sander, Jacob B Hjelmborg, Christine Dalgård, Rasmus Jensen, Michael Larsen   +8 more
doaj   +1 more source