Results 21 to 30 of about 31,224 (320)

Topographic Distribution and Progression of Soft Drusen Volume in Age-Related Macular Degeneration Implicate Neurobiology of Fovea

Investigative Ophthalmology and Visual Science, 2021
Purpose To refine estimates of macular soft drusen abundance in eyes with age-related macular degeneration (AMD) and evaluate hypotheses about drusen biogenesis, we investigated topographic distribution and growth rates of drusen by optical coherence ...
A. Pollreisz, G. Reiter, H. Bogunović, L. Baumann, Astrid Jakob, F. Schlanitz, S. Sacu, C. Owsley, K. Sloan, C. Curcio, U. Schmidt-Erfurth   +10 more
semanticscholar   +1 more source

Validation of a Novel Automated Algorithm to Measure Drusen Volume and Area Using Swept Source Optical Coherence Tomography Angiography

Translational Vision Science & Technology, 2021
Purpose The purpose of this study was to validate a novel automated swept source optical coherence tomography angiography (SS-OCTA) algorithm to measure elevations of the retinal pigment epithelium (RPE) in eyes with nonexudative age-related macular ...
Xiaoshuang Jiang, Mengxi Shen, Liang Wang, L. de Sisternes, M. Durbin, W. Feuer, P. Rosenfeld, Giovanni Gregori   +7 more
semanticscholar   +1 more source

Macular dysfunction in drusen maculopathy assessed with multifocal electroretinogram and optical coherence tomography

Clinical Ophthalmology, 2013
Jose G Garcia-Garcia,1,2 Jose M Ruiz-Moreno,1 Kristina Holm,2 Sten Andréasson,2 Monica Lövestam-Adrian21Department of Ophthalmology, University of Castilla La Mancha, Albacete, Spain; 2Department of Ophthalmology, University of Lund, Lund ...
Garcia-Garcia JG, Ruiz-Moreno JM, Holm K, Andreasson S, Lövestam-Adrian M   +4 more
doaj   +3 more sources

Analysis of Macular Drusen and Blood Test Results in 945 Macaca fascicularis. [PDF]

PLoS ONE, 2016
Age-dependent formation of macular drusen caused by the focal accumulation of extracellular deposits beneath the retinal pigment epithelium precede the development of age-related macular degeneration (AMD), one of the leading causes of blindness ...
Koji M Nishiguchi, Yu Yokoyama, Yusuke Fujii, Kosuke Fujita, Yusuke Tomiyama, Ryo Kawasaki, Toshinori Furukawa, Fumiko Ono, Nobuhiro Shimozawa, Mutsumi Togo, Michihiro Suzuki, Toru Nakazawa   +11 more
doaj   +1 more source

Bilaterality of drusen. [PDF]

British Journal of Ophthalmology, 1990
The characteristics of drusen in 81 patients with bilateral drusen as a manifestation of age related disease were analysed for symmetry between the two eyes. It was found that there was close concordance with respect to drusen size, number, density, and fluorescence which was greater than would have been expected by chance alone.
I C Chisholm, Alan C. Bird, M J Barondes, D. Pauleikhoff, Darwin C Minassian   +4 more
openaire   +3 more sources

OCT Based Interpretation of the Optic Nerve Head Anatomy and Prevalence of Optic Disc Drusen in Patients with Idiopathic Intracranial Hypertension (IIH)

Life, 2021
We aimed to systematically examine the optic nerve head anatomy in patients with idiopathic intracranial hypertension (IIH) using a standardized optical coherence tomography (OCT) protocol.
E. A. Wibroe, L. Malmqvist, S. Hamann
semanticscholar   +1 more source

Characterization of Drusen and Hyperreflective Foci as Biomarkers for Disease Progression in Age-Related Macular Degeneration Using Artificial Intelligence in Optical Coherence Tomography.

JAMA ophthalmology, 2020
Importance The morphologic changes and their pathognomonic distribution in progressing age-related macular degeneration (AMD) are not well understood. Objectives To characterize the pathognomonic distribution and time course of morphologic patterns in ...
S. Waldstein, Wolf-Dieter Vogl, H. Bogunović, A. Sadeghipour, Sophie Riedl, U. Schmidt-Erfurth   +5 more
semanticscholar   +1 more source

Increased retinal drusen in IgA glomerulonephritis are further evidence for complement activation in disease pathogenesis

Scientific Reports, 2022
Drusen are retinal deposits comprising cell debris, immune material and complement that are characteristic of macular degeneration but also found in glomerulonephritis.
P. Harraka, Tony Wightman, Sarah Akom, Kieran Sandhu, Deb Colville, Andrew Catran, David Langsford, Timothy Pianta, David Barit, Frank Ierino, Alison Skene, Heather Mack, Judy Savige   +12 more
doaj   +1 more source

Drusen, AMD, and history [PDF]

Graefe's Archive for Clinical and Experimental Ophthalmology, 2015
It is becoming increasingly difficult to get manuscripts on (ophthalmic) history accepted by medical journals. This, in spite of the fact that studying the history of disorders yields valuable insights, which can offer new approaches to solving problems of pathophysiology or delimiting disease entities.
Paulus T. V. M. de Jong, Paulus T. V. M. de Jong   +1 more
openaire   +4 more sources

Clinical Characteristics of Neovascular Age-Related Macular Degeneration without Typical Drusen

Journal of Ophthalmology, 2021
Purpose. To evaluate the clinical characteristics of neovascular age-related macular degeneration (nAMD) patients without typical drusen. Methods. We retrospectively studied 165 eyes in 165 patients with treatment-naïve nAMD, including typical AMD and ...
Hiroyuki Kamao, Katsutoshi Goto, Kento Matsuno, Kenichi Mizukawa, Atsushi Miki, Junichi Kiryu   +5 more
doaj   +1 more source