Results 21 to 30 of about 25,200 (252)

Evaluation of the microperimetry in eyes with cuticular drusen

Scientific Reports, 2022
Retinal sensitivity may vary by subtypes of cuticular drusen. This retrospective study included 52 eyes of 32 patients with cuticular drusen. All the patients underwent assessment of best-corrected visual acuity (BCVA), spectral-domain optical coherence ...
Seung Wan Nam, Jung Hwa Lee, Zeeyoon Byun, Don-Il Ham, Mingui Kong   +4 more
doaj   +1 more source

Extracellular vesicles released by human retinal pigment epithelium mediate increased polarised secretion of drusen proteins in response to AMD stressors

Journal of Extracellular Vesicles, 2021
Age‐related macular degeneration (AMD) is a leading cause of blindness worldwide. Drusen are key contributors to the etiology of AMD and the ability to modulate drusen biogenesis could lead to therapeutic strategies to slow or halt AMD progression.
Miguel Flores‐Bellver, Jason Mighty, Silvia Aparicio‐Domingo, Kang V. Li, Cui Shi, Jing Zhou, Hannah Cobb, Patrick McGrath, German Michelis, Patricia Lenhart, Ganna Bilousova, Søren Heissel, Michael J. Rudy, Christina Coughlan, Andrew E. Goodspeed, S. Patricia Becerra, Stephen Redenti, M. Valeria Canto‐Soler   +17 more
doaj   +1 more source

Integrity of the Hyperreflective Layer in the Inner Choroid in Eyes with Drusen

Ophthalmology and Therapy, 2023
Introduction This study aimed to compare the integrity of the hyperreflective layer of the inner choroid in eyes with and without drusen. Methods Swept-source optical coherence tomography images of patients with drusen and normal controls were reviewed ...
Young Ho Kim, Cheolmin Yun, Jaeryung Oh
doaj   +1 more source

Population-Based Prevalence and 5-Year Change of Soft Drusen, Pseudodrusen, and Pachydrusen in a Japanese Population

Ophthalmology Science, 2021
Purpose: To elucidate the prevalence of soft drusen, pseudodrusen, and pachydrusen and their 5-year changes in a Japanese population. Design: Longitudinal population-based cohort study conducted from 2013 through 2017. Participants: Residents 40 years of
Miki Sato-Akushichi, MD, Reiko Kinouchi, MD, PhD, Satoshi Ishiko, MD, PhD, Kazuomi Hanada, MD, PhD, Hiroki Hayashi, Daiki Mikami, Shinji Ono, MD, PhD, Yasuo Yanagi, MD, PhD   +7 more
doaj   +1 more source

Increased retinal drusen in IgA glomerulonephritis are further evidence for complement activation in disease pathogenesis

Scientific Reports, 2022
Drusen are retinal deposits comprising cell debris, immune material and complement that are characteristic of macular degeneration but also found in glomerulonephritis.
P. Harraka, Tony Wightman, Sarah Akom, Kieran Sandhu, Deb Colville, Andrew Catran, David Langsford, Timothy Pianta, David Barit, Frank Ierino, Alison Skene, Heather Mack, Judy Savige   +12 more
doaj   +1 more source

Association of drusen deposition with choroidal intercapillary pillars in the aging human eye [PDF]

, 2004
PURPOSE. To determine the pattern of drusen accumulation with age and to investigate the initial sites of deposition and their relationship to choroidal capillaries in human donor eyes from the eye bank of Moorfields Eye Hospital.METHODS.
Al Hosaini, H, Bird, AC, Jeffery, G, Lengyel, I, Luthert, P, Tufail, A   +5 more
core   +1 more source

Cuticular drusen

Indian Journal of Ophthalmology - Case Reports, 2021
A 30-year-old woman presented to the OPD, and during the course of her retinal examination she was seen to have multiple drusen in both the eyes. Based on her age, drusen appearance, distribution, autofluorescence, star in the sky appearance on angiography, and sub-RPE location on SD-OCT, she was diagnosed as having Cuticular ...
Saarang Hansraj, Aliya Sultana, Rajalingam Vairagyam   +2 more
openaire   +1 more source

Clinical manifestations of cuticular drusen in Korean patients

Scientific Reports, 2020
Cuticular drusen show some similarities to and differences from soft drusen in age-related macular degeneration (AMD) and might thus be a unique AMD subtype. Previous studies on cuticular drusen were performed mainly in white ethnic groups, but AMD shows
Dong Hoon Shin, Mingui Kong, Gyule Han, Jong Chul Han, Don-Il Ham   +4 more
doaj   +1 more source

Analysis of Macular Drusen and Blood Test Results in 945 Macaca fascicularis. [PDF]

PLoS ONE, 2016
Age-dependent formation of macular drusen caused by the focal accumulation of extracellular deposits beneath the retinal pigment epithelium precede the development of age-related macular degeneration (AMD), one of the leading causes of blindness ...
Koji M Nishiguchi, Yu Yokoyama, Yusuke Fujii, Kosuke Fujita, Yusuke Tomiyama, Ryo Kawasaki, Toshinori Furukawa, Fumiko Ono, Nobuhiro Shimozawa, Mutsumi Togo, Michihiro Suzuki, Toru Nakazawa   +11 more
doaj   +1 more source

An Evaluation of a Battery of Functional and Structural Tests as Predictors of Likely Risk of Progression of Age-Related Macular Degeneration. [PDF]

, 2018
Purpose: To evaluate the ability of visual function and structural tests to identify the likely risk of progression from early/intermediate to advanced AMD, using the Age-Related Eye Disease Study (AREDS) simplified scale as a surrogate for risk of ...
Bailey, C., Binns, A. M., Margrain, T. H., Robinson, D. G.   +3 more
core   +3 more sources