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Drusen, an Old but New Frontier [PDF]
Retina, 2010 Early in the education of ophthalmologists the student is introduced to the concept of drusen. The material is presented in an efficient unquestioning manner: drusen are formed by material under the retinal pigment epithelium (RPE). This material seems to have varying composition, which may have clinically recognizable correlates.1-4 Classification ...
Richard F. Spaide +2 more
openalex +4 more sources
British Journal of Ophthalmology, 1990 The characteristics of drusen in 81 patients with bilateral drusen as a manifestation of age related disease were analysed for symmetry between the two eyes. It was found that there was close concordance with respect to drusen size, number, density, and fluorescence which was greater than would have been expected by chance alone.
I C Chisholm +4 more
openaire +3 more sources
Drusen, AMD, and history [PDF]
Graefe's Archive for Clinical and Experimental Ophthalmology, 2015 It is becoming increasingly difficult to get manuscripts on (ophthalmic) history accepted by medical journals. This, in spite of the fact that studying the history of disorders yields valuable insights, which can offer new approaches to solving problems of pathophysiology or delimiting disease entities.
Paulus T. V. M. de Jong +1 more
openaire +4 more sources
Scientific Reports, 2022 Drusen are retinal deposits comprising cell debris, immune material and complement that are characteristic of macular degeneration but also found in glomerulonephritis.
P. Harraka +12 more
doaj +1 more source
JAMA ophthalmology, 2020 Importance The morphologic changes and their pathognomonic distribution in progressing age-related macular degeneration (AMD) are not well understood. Objectives To characterize the pathognomonic distribution and time course of morphologic patterns in ...
S. Waldstein +5 more
semanticscholar +1 more source
Clinical manifestations of cuticular drusen in Korean patients
Scientific Reports, 2020 Cuticular drusen show some similarities to and differences from soft drusen in age-related macular degeneration (AMD) and might thus be a unique AMD subtype. Previous studies on cuticular drusen were performed mainly in white ethnic groups, but AMD shows
Dong Hoon Shin +4 more
doaj +1 more source
Dynamic Drusen Remodelling in Participants of the Nutritional AMD Treatment-2 (NAT-2) Randomized Trial. [PDF]
PLoS ONE, 2016 PURPOSE:To evaluate the dynamic remodeling of drusen in subjects with unilateral neovascular age-related macular degeneration (AMD) receiving a three-year course of oral docosahexaenoic acid (DHA) or placebo. SETTING:Institutional setting.
Giuseppe Querques +9 more
doaj +1 more source
An Evaluation of a Battery of Functional and Structural Tests as Predictors of Likely Risk of Progression of Age-Related Macular Degeneration. [PDF]
, 2018 Purpose: To evaluate the ability of visual function and structural tests to identify the likely risk of progression from early/intermediate to advanced AMD, using the Age-Related Eye Disease Study (AREDS) simplified scale as a surrogate for risk of ...
Bailey, C. +3 more
core +3 more sources
Analysis of Macular Drusen and Blood Test Results in 945 Macaca fascicularis. [PDF]
PLoS ONE, 2016 Age-dependent formation of macular drusen caused by the focal accumulation of extracellular deposits beneath the retinal pigment epithelium precede the development of age-related macular degeneration (AMD), one of the leading causes of blindness ...
Koji M Nishiguchi +11 more
doaj +1 more source
Translational Vision Science & Technology, 2021 Purpose Drusen are dynamic sub-RPE deposits that are risk factors for late-stage age-related macular degeneration (AMD). Here we show a new imaging method using flood-illumination adaptive optics (FIAO) that reveal drusen with high contrast and ...
E. Rossi +16 more
semanticscholar +1 more source