Results 41 to 50 of about 22,596 (200)

Integrative analysis of the choroid by quantifying Haller vessel and choriocapillaris parameters in different drusen subtypes

open access: yesScientific Reports, 2021
This study aimed to quantify the Haller vessel and choriocapillaris (CC) parameters in drusen subtypes in nonexudative age-related macular degeneration (AMD) and pachydrusen.
Hyungwoo Lee   +6 more
doaj   +1 more source

Association of Retinal Vascular Caliber and Age-Related Macular Degeneration in Patients With the Acquired Immunodeficiency Syndrome. [PDF]

open access: yes, 2018
PurposeTo evaluate the relationship between retinal vascular caliber and AMD in patients with AIDS.MethodsParticipants enrolled in the Longitudinal Study of the Ocular Complications of AIDS had retinal photographs taken at enrollment.
Danis, Ronald P   +4 more
core   +1 more source

Morphometric parameters of the optic disc and peripapillary retina in children in cases of congenital pathology

open access: yesРоссийский офтальмологический журнал, 2022
Purpose: to study the nature of changes in morphological parameters of the children’s optic disc and peripapillary retina in cases of congenital pathology.Material and methods.
T. V. Sudovskaya, L. V. Kogoleva
doaj   +1 more source

Prevalence of age-related macular degeneration in Nakuru, Kenya: a cross-sectional population-based study. [PDF]

open access: yes, 2013
BACKGROUND: Diseases of the posterior segment of the eye, including age-related macular degeneration (AMD), have recently been recognised as the leading or second leading cause of blindness in several African countries.
Bastawrous, Andrew   +5 more
core   +6 more sources

Dietary fatty acids and lipoproteins on progression of age-related macular degeneration [PDF]

open access: yes, 2017
Age-related macular degeneration (AMD) is a medical condition of central loss vision and blindness. Numerous studies have revealed that changes on certain dietary fatty acids (FAs) could have useful for AMD management.
Abia González, María del Rocío   +5 more
core   +3 more sources

Developing an image-based grading scale for peripheral drusen to investigate associations of peripheral drusen type with age-related macular degeneration

open access: yesScientific Reports
Age-related macular degeneration (AMD) is a leading cause of blindness. It is associated with peripheral drusen which has not been categorized. We investigated peripheral drusen to validate an image grading system and to understand possible associations ...
Paripoorna Sharma   +4 more
doaj   +1 more source

Photodegradable Hydrogels for On‐Demand Modeling of Age‐Related Spatiotemporal ECM Deformation

open access: yesSmall, EarlyView.
A light‐tunable PEG hydrogel enables on‐demand, spatiotemporal modeling of drusen‐like ECM bulges in the aging outer retina. By precisely controlling bulge size, the platform reveals how retinal pigment epithelium morphology adapts to topographical changes without disrupting actin cytoskeleton or polarity, effectively mimicking early ageing before ...
Felix Reul   +8 more
wiley   +1 more source

Epithelial phenotype restoring drugs suppress macular degeneration phenotypes in an iPSC model

open access: yesNature Communications, 2021
Age-related macular degeneration is characterized by lipid-rich drusen deposits underneath the retinal pigment epithelium (RPE). Here the authors report an in vitro iPSC-RPE model for AMD that recapitulates drusen and RPE atrophy, and identify two drugs ...
Ruchi Sharma   +22 more
doaj   +1 more source

Humanin G (HNG) protects age-related macular degeneration (AMD) transmitochondrial ARPE-19 cybrids from mitochondrial and cellular damage. [PDF]

open access: yes, 2017
Age-related macular degeneration (AMD) ranks third among the leading causes of visual impairment with a blindness prevalence rate of 8.7%. Despite several treatment regimens, such as anti-angiogenic drugs, laser therapy, and vitamin supplementation ...
Chwa, Marilyn   +6 more
core   +1 more source

Power and clinical utility of mesopic microperimetry analysis strategies in age‐related macular degeneration

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose This study evaluates whether mesopic microperimetry (MMP) provides a more robust measure of retinal function compared to visual acuity (VA) in age‐related macular degeneration (AMD) clinical trials, with a focus on optimal analysis strategies. Method Fellow‐eyes of unilateral neovascular AMD were prospectively studied.
Francesco Cinque   +9 more
wiley   +1 more source

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