Results 331 to 340 of about 114,219 (358)
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dsRNA-protein interactions studied by molecular dynamics techniques. Unravelling dsRNA recognition by DCL1

Archives of Biochemistry and Biophysics, 2016
Double stranded RNA (dsRNA) participates in several biological processes, where RNA molecules acquire secondary structure inside the cell through base complementarity. The double stranded RNA binding domain (dsRBD) is one of the main protein folds that is able to recognize and bind to dsRNA regions. The N-terminal dsRBD of DCL1 in Arabidopsis thaliana (
Rodolfo M. Rasia   +5 more
openaire   +4 more sources

Activation of the dsRNA-Dependent Kinase

1994
The double-stranded RNA (dsRNA)-dependent protein kinase, designated here as dsI, but also referred to as DAI, Pl kinase, p68 kinase and PI/eIF-2α protein kinase, is an interferon-induced serine/threonine protein kinase. It is uniquely distinguished from other protein kinases in that its activation to a functional enzyme, and in some cases prevention ...
R. A. Petryshyn, J. Li, R. Judware
openaire   +3 more sources

Packaging in dsRNA Viruses

2011
Several families of viruses have segmented genomes with 3-12 chromosomes. They are capable of packaging these segments in a precise manner so that each virus particle contains one each of the genomic segments. The Cystoviridae are a family of bacteriophages that contain three genomic segments of dsRNA.
openaire   +3 more sources

The next generation of insecticides: dsRNA is stable as a foliar-applied insecticide.

Pest Management Science, 2016
BACKGROUND RNAi is a powerful tool used to study gene function. It also has been hypothesized to be a promising new method for control of insect pests on crops, although the perceived instability of dsRNA in the environment has constrained thinking about
Keri San Miguel, J. G. Scott
semanticscholar   +1 more source

Receptor-dsRNA-Receptor

Science Signaling, 2008
Toll-like receptors recognize molecules associated with pathogens and initiate inflammatory responses. For example, Toll-like receptor 3 (TLR3) recognizes double-stranded RNA (dsRNA), an intermediate viral replication. The TLR3 ectodomain binds as a dimer to dsRNA, but the molecular basis for signaling remains unclear.
openaire   +2 more sources

dsRNA in Diagnosis

2019
This chapter describes the practical value for attempting to detect and describes the double-stranded (dsRNAs) lies in the ease with which they can be isolated and characterized. Most diagnostic laboratories recognize the value of less specific tests which can be used in addition to specific tests in the early testing stages, especially when the ...
openaire   +2 more sources

Contributions of dsRNases to differential RNAi efficiencies between the injection and oral delivery of dsRNA in Locusta migratoria.

Pest Management Science, 2019
BACKGROUND The efficiency of RNA interference (RNAi) varies considerably among different insect species, and there is growing evidence to suggest that degradation of double-stranded (dsRNA) prior to uptake is an important factor that limits the ...
Huifang Song   +9 more
semanticscholar   +1 more source

dsRNA killer systems in yeast [PDF]

open access: possible, 1987
Killer yeasts, first identified by Bevan and Makower (1963), secrete proteinaceous toxins which kill other, sensitive yeasts. It is now more than a decade since the cytoplasmic determinants associated with the killing phenomenon were shown to be encapsidated dsRNA molecules.
Diane J. Mitchell, E. Alan Bevan
openaire   +1 more source

Topical dsRNA delivery induces gene silencing and mortality in the pea aphid.

Pest Management Science, 2019
BACKGROUND With the growing number of available aphid genomes and transcriptomes, an efficient and easy-to-adapt tool for gene function study is urgently required.
J. Niu   +13 more
semanticscholar   +1 more source

Continuity of the dsRNA genome of bluetongue virus

Current Microbiology, 1978
The duplex RNA genome of bluetongue virus, extracted under acidic conditions with sodium dodecyl sulfate and phenol, is an unfragmented continuous structure. Most genomes appeared as a rosette with 10 loops (genes) emanating from a central crescent- or doughnutshaped area. The genome has a mean length of ca.
Thomas E. Walton   +2 more
openaire   +3 more sources

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