Results 11 to 20 of about 4,194,149 (156)
Assessment of glymphatic function in narcolepsy using DTI-ALPS index [PDF]
Sleep Medicine, 2023 Sleep is a modulator of glymphatic activity which is altered in various sleep disorders. Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness (EDS), rapid onset of rapid eye movement (REM) sleep, cataplexy, disturbed night sleep with fragmentation.
Ekim Gumeler +4 more
core +6 more sources
Changes in DTI-ALPS index and its associations with neuronal damage in Lewy body disease [PDF]
Parkinsonism & Related DisordersDysfunction of the glymphatic system is thought to lead to build up of toxic proteins including β-amyloid and α-synuclein, and thus may be involved in dementia with Lewy bodies (DLB) and Alzheimer's disease (AD). The Diffusion Tensor Image Analysis Along the Perivascular Space (DTI-ALPS) index has been proposed as a marker of glymphatic function.To ...
M.J. Firbank +13 more
core +6 more sources
DTI-ALPS index decreased in patients with Type 2 Diabetes Mellitus [PDF]
Frontiers in NeuroscienceBackgroundsType 2 Diabetes Mellitus (T2DM) has become a significant global public health issue, characterized by a rising prevalence and associated deficits across multiple organ systems. Our study aims to utilize the DTI-ALPS technique to assess the change of ALPS index in T2DM patients, and to explore whether such changes are correlated with ...
Shuncheng Yu +8 more
openaire +4 more sources
Glymphatic System Assessment Using DTI-ALPS in Age-Dependent Neurodegenerative Diseases [PDF]
Анналы клинической и экспериментальной неврологииIntroduction. Dysfunction of the glymphatic system glymphatic system of the brain is considered a pathogenetic factor in some age-dependent neurodegenerative diseases, including Alzheimer's disease (AD), dementia with Lewy bodies (DLB), Parkinson's ...
Alina A. Liaskovik +6 more
doaj +3 more sources
Assessment of the glymphatic dysfunction in amyotrophic lateral sclerosis using the diffusion tensor imaging along the perivascular spaces index: a pilot study [PDF]
Frontiers in Aging NeuroscienceBackgroundThe glymphatic system plays a critical role in clearing interstitial waste from the brain. Dysfunction of this system has been linked to various neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS).
Seol-Hee Baek +4 more
doaj +2 more sources
Renal FailureObjectives To investigate glymphatic function in nondialysis-dependent ESRD (ND-ESRD) patients with diabetic kidney disease (DKD) or non-DKD using the diffusion tensor image analysis along the perivascular space (DTI-ALPS) method and choroid plexus (CP ...
Bingxin Yu +7 more
doaj +2 more sources
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease MonitoringINTRODUCTION We evaluated whether the brain glymphatic drainage function estimated by the diffusion tensor imaging along the perivascular space (DTI‐ALPS) index relates to white matter (WM) integrity, Alzheimer's disease (AD) neuropathology, resting ...
Susanna Lopez +41 more
doaj +2 more sources
Scientific ReportsIn recent years, the glymphatic system has received increasing attention due to its possible implications in biological mechanisms associated with neurodegeneration.
Tommaso Costa +8 more
doaj +2 more sources
Altered perivascular-aligned diffusivity in postherpetic neuralgia assessed by the DTI-ALPS index
Frontiers in NeuroscienceBackgroundThe glymphatic system has been proposed as a key pathway for interstitial fluid clearance in the brain, but its role in chronic neuropathic pain conditions such as postherpetic neuralgia (PHN) remains unclear.
Daeseok Oh +4 more
doaj +2 more sources
Early Improvement in Interstitial Fluid Flow in Patients With Severe Carotid Stenosis After Angioplasty and Stenting [PDF]
Journal of StrokeBackground and Purpose This study aimed to investigate early changes in interstitial fluid (ISF) flow in patients with severe carotid stenosis after carotid angioplasty and stenting (CAS).
Chia-Hung Wu +8 more
doaj +3 more sources