Results 121 to 130 of about 687,252 (300)

Untested Assumptions and Tenuous Evidence: A Critique of the Dual-Process Account of Moral Judgment

open access: yesBehavioral Sciences
The dual-process theory of moral judgment asserts that moral judgments come about because of the operation of either of two independent decision processes, often described as a cognitive/rational process and an intuitive/affective process. In some cases,
Philip T. Quinlan, Dale J. Cohen
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

APPLICATIONS OF DUAL THEORY IN FISHERIES: A SURVEY

open access: yes
This paper surveys empirical studies that utilize the theory of the firm and dual theory to reveal economic and technological conditions of fish harvesting firms.
Jensen, Carsten Lynge
core  

Nahm’s equation and the search for classical solutions in Yang-Mills theory [PDF]

open access: yes, 1987
The history of the theory of magnetic monopoles in classical electrodynamics and unified gauge theories is reviewed, and the Atiyah-Ward and Atiyah-Drinfe1d-Hitchin-Man in constructions of exact classical solutions to the self-dual Yang-Mills equations
Wainwright, P.R., Wainwright, P.R
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

The complex phenomenon of dysrational antibiotics prescribing decisions in German primary healthcare: a qualitative interview study using dual process theory. [PDF]

open access: yesAntimicrob Resist Infect Control, 2020
Poss-Doering R   +6 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Portfolio Selection with minimum transaction lots: an approach with dual expected utility [PDF]

open access: yes
In this paper we analyse the portfolio selectionproblem with minimum transactionlots in the context of non-expected utility theory. We assume that the decisionmaker ranks the alternatives by using a specific DualExpectedUtility.
Floriana Filippini, Marisa Cenci
core  

Home - About - Disclaimer - Privacy