Results 61 to 70 of about 6,647,962 (373)
Slicely Countably Determined Banach spaces [PDF]
, 2009 We introduce the class of slicely countably determined Banach spaces which contains in particular all spaces with the RNP and all spaces without copies of $\ell_1$. We present many examples and several properties of this class.
Aviles, Antonio +4 more
core +4 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Vector subdifferentials and tangent cones
Journal of Numerical Analysis and Approximation Theory, 2005 Following the Rockafellar's definition for the subdifferential of a real map we define a vector subdifferential using the normal cone to the epigraph of the function.
Cristina Stamate
doaj +2 more sources
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
The Lorentz space as a dual space [PDF]
Proceedings of the American Mathematical Society, 1984 If ( X , S , μ ) (X,S,\mu ) is a finite, completely nonatomic measure space and ϕ ( t ) = t 1 / p ( p &
openaire +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Geometrical approach to duality in N=1 supersymmetric theories [PDF]
, 1997 We investigate the geometry of the moduli spaces of dual electric and magnetic N=1 supersymmetric field theories. Using the SU(N_c) gauge group as a guideline we show that the electric and magnetic moduli spaces coincide for a suitable choice of the ...
Brax, Ph, Grojean, C., Savoy, C. A.
core +1 more source