miR-93/miR-106b/miR-375-CIC-CRABP1: a novel regulatory axis in prostate cancer progression [PDF]
Capicua (CIC) has been implicated in pathogenesis of spinocerebellar ataxia type-1 (SCA1) neurodegenerative disease and some types of cancer; however, the role of CIC in prostate cancer remains unknown.
Cho, YM +9 more
core +1 more source
Assessment of Genetic Mutations DMD, DYSF, EMD, LMNA, DUX4, DMPK, ZNF9, PABPN1 Genes Induction Duchenne Muscular Dystrophy [PDF]
, 2017 Shahin Asadi
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Targeted epigenetic repression by CRISPR/dSaCas9 suppresses pathogenic DUX4-fl expression in FSHD [PDF]
, 2020 Charis L. Himeda +2 more
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DUX4, the rockstar of embryonic genome activation?
The International Journal of Developmental BiologyPeer ...
Nykänen, Sonja, Vuoristo, Sanna
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DUX4 is a common driver of immune evasion and immunotherapy failure in metastatic cancers
eLifeCancer immune evasion contributes to checkpoint immunotherapy failure in many patients with metastatic cancers. The embryonic transcription factor DUX4 was recently characterized as a suppressor of interferon-γ signaling and antigen presentation that is ...
Jose Mario Bello Pineda +1 more
doaj +1 more source
Genetically Engineered Mouse Models of CIC-DUX4 Sarcoma Reveal an Unexpected Sensitivity to Histone Deacetylase (HDAC) Inhibition [PDF]
, 2023 Peter G. Hendrickson +5 more
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DUX4 Transcript Knockdown with Antisense 2′-O-Methoxyethyl Gapmers for the Treatment of Facioscapulohumeral Muscular Dystrophy [PDF]
, 2020 Kenji Rowel Q. Lim +9 more
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DUX4HD2-DNAERG structure reveals new insight into DUX4-Responsive-Element [PDF]
Leukemia, 2018 Xue Dong +4 more
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Expression of the CIC-DUX4 fusion oncoprotein mimics human CIC-rearranged sarcoma in genetically engineered mouse models [PDF]
, 2023 Peter G. Hendrickson +7 more
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