Spray‐induced gene silencing to control plant pathogenic fungi: A step‐by‐step guide
Journal of Integrative Plant Biology, Volume 67, Issue 3, Page 801-825, March 2025.Spray‐induced gene silencing is an innovative, eco‐friendly technology for controlling plant fungal diseases by applying RNA molecules that silence key fungal genes via RNA interference. This guide explores how to develop safe and effective formulations based on current knowledge, aiming to improve their efficacy under real‐world conditions.
Sandra Mosquera +6 more
wiley +1 more source
Assembly and activation of dynein–dynactin by the cargo adaptor protein Hook3
bioRxiv, 2016 Metazoan cytoplasmic dynein moves processively along microtubules with the aid of dynactin and an adaptor protein that joins dynein and dynactin into a stable ternary complex.
C. M. Schroeder, R. Vale
semanticscholar +1 more source
Cytoplasmic dynein and its regulatory proteins in Golgi pathology in nervous system disorders
Frontiers in Neuroscience, 2015 The Golgi apparatus is a dynamic organelle involved in processing and sorting of lipids and proteins. In neurons, the Golgi apparatus is important for the development of axons and dendrites and maintenance of their highly polarized morphology.
Dick eJaarsma, Casper eHoogenraad
doaj +1 more source
A tunable LIC1-adaptor interaction modulates dynein activity in a cargo-specific manner
Nature Communications, 2020 Activating adaptors that link dynein to its general cofactor dynactin recruit specific cargoes and regulate dynein’s activity and processive motility in retrograde transport.
In-Gyun Lee +4 more
doaj +1 more source
Structure of dynein–dynactin on microtubules shows tandem adaptor binding
Nature, 2022 Sami Chaaban, A. Carter
semanticscholar +1 more source
HIV-1 Engages a Dynein-Dynactin-BICD2 Complex for Infection and Transport to the Nucleus
Journal of Virology, 2018 During HIV-1 infection, the virus must travel across the cytoplasm to enter the nucleus. The host cell motor protein complex dynein has been implicated in HIV-1 intracellular transport. We show that expression of the dynein heavy chain, components of the
Stephanie K. Carnes +2 more
semanticscholar +1 more source
Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility
Nature Structural & Molecular Biology, 2017 Cytoplasmic dynein is a protein complex that transports molecular cargo along microtubules (MTs), playing a key role in the intracellular trafficking network.
D. Grotjahn +5 more
semanticscholar +1 more source
A Novel De Novo Splice Acceptor Variant in BICD2 Is Associated With Spinal Muscular Atrophy
American Journal of Medical Genetics Part A, Volume 197, Issue 4, April 2025.
Giulia F. Del Gobbo +7 more
wiley +1 more source
Dynactin drives dynein without microtubule binding [PDF]
The Journal of Cell Biology, 2007 Dynactin might bind to and organize microtubules. But it doesn't need to bind microtubules to jump-start dynein motoring, Kim et al. report on page 641. Figure 1 Organelle cargo distribution is similar in wild-type cells (left) and cells expressing nonmicrotubule-binding dynactin (right), indicating that transport remains intact ...
openaire +2 more sources
Ndel1 disfavors dynein–dynactin–adaptor complex formation in two distinct ways
Journal of Biological Chemistry, 2023 Sharon R. Garrott +5 more
semanticscholar +1 more source