Results 131 to 140 of about 9,677 (245)

The mammalian dynein/dynactin complex is a strong opponent to kinesin in a tug-of-war competition

Nature Cell Biology, 2016
Kinesin and dynein motors transport intracellular cargos bidirectionally by pulling them in opposite directions along microtubules, through a process frequently described as a ‘tug of war’. While kinesin produces 6 pN of force, mammalian dynein was found
V. Belyy, Max A. Schlager, H. Foster, Armando Reimer, A. Carter, A. Yildiz   +5 more
semanticscholar   +1 more source

Ultrastructural analysis of the dynactin complex: an actin-related protein is a component of a filament that resembles F-actin. [PDF]

, 1994
Dorothy A. Schafer, Steven R. Gill, John A. Cooper, John E. Heuser, Trina A. Schroer   +4 more
openalex   +1 more source

Role of Dynactin in Endocytic Traffic: Effects of Dynamitin Overexpression and Colocalization with CLIP-170 [PDF]

, 1999
Caterina Valetti, Dawn M. Wetzel, Michael Schrader, M. Josh Hasbani, Steven R. Gill, Thomas E. Kreis, Trina A. Schroer   +6 more
openalex   +1 more source

Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation [PDF]

, 2001
Bonnie J. Howell, B.F. McEwen, Julie C. Canman, David B. Hoffman, Emily M Farrar, C L Rieder, Edward D. Salmon   +6 more
openalex   +3 more sources

Human dynein-dynactin is a fast processive motor in living cells

bioRxiv, 2023
Vikash Verma, Patricia Wadsworth, T. Maresca   +2 more
semanticscholar   +1 more source

Affinity Chromatography Demonstrates a Direct Binding between Cytoplasmic Dynein and the Dynactin Complex [PDF]

, 1995
Sher Karki, Erika L.F. Holzbaur
openalex   +1 more source

Dynactin p150 promotes processive motility of DDB complexes by minimizing diffusional behavior of dynein

bioRxiv, 2019
Cytoplasmic dynein is activated by forming a complex with dynactin and the adaptor protein BicD2. We used Interferometric Scattering (iSCAT) microscopy to track dynein-dynactin-BicD2 (DDB) complexes in vitro and developed a regression-based algorithm to ...
Qingzhou Feng, A. Gicking, W. Hancock
semanticscholar   +1 more source

Hexameric NuMA:LGN structures promote multivalent interactions required for planar epithelial divisions

Nature Communications, 2019
LGN and NuMA link epithelial polarity sites with astral microtubules and associate with dynein, but the architecture of such cortical force-generating complexes is unknown.
Laura Pirovano, Simone Culurgioni, Manuel Carminati, Andrea Alfieri, Silvia Monzani, Valentina Cecatiello, Chiara Gaddoni, Francesca Rizzelli, James Foadi, Sebastiano Pasqualato, Marina Mapelli   +10 more
doaj   +1 more source

Cytoplasmic Dynein and Dynactin Are Required for the Transport of Microtubules into the Axon [PDF]

, 1998
Fridoon Jawad Ahmad, Christophe J. Echeverri, Richard B. Vallee, Peter W. Baas   +3 more
openalex   +1 more source

Functional Analysis of Dynactin and Cytoplasmic Dynein in Slow Axonal Transport [PDF]

, 1996
James F. Dillman, Lewis P. Dabney, Sher Karki, Bryce M. Paschal, Erika L.F. Holzbaur, K. Kevin Pfister   +5 more
openalex   +1 more source