Results 1 to 10 of about 64,052 (190)
SUSTAINED EXOCYTOSIS AFTER ACTION POTENTIAL-LIKE STIMULATION AT LOW FREQUENCIES IN MOUSE CHROMAFFIN CELLS DEPENDS ON A DYNAMIN-DEPENDENT FAST ENDOCYTOTIC PROCESS [PDF]
Frontiers in Cellular Neuroscience, 2016 Under basal conditions the action potential firing rate of adrenal chromaffin cells is lower than 0.5 Hz. The maintenance of the secretory response at such frequencies requires a continuous replenishment of releasable vesicles.
José Moya-Díaz +7 more
doaj +3 more sources
Frontiers in Cell and Developmental Biology, 2022 Dynamin is an endocytic protein that functions in vesicle formation by scission of invaginated membranes. Dynamin maintains the structure of foot processes in glomerular podocytes by directly and indirectly interacting with actin filaments.
Eriko Hamasaki +16 more
doaj +1 more source
Synthesis and Effect of Conformationally Locked Carbocyclic Guanine Nucleotides on Dynamin
Biomolecules, 2022 Guanine nucleotides can flip between a North and South conformation in the ribose moiety. To test the enzymatic activity of GTPases bound to nucleotides in the two conformations, we generated methanocarba guanine nucleotides in the North or South ...
Kiran S. Toti +4 more
doaj +1 more source
Entry pathways of herpes simplex virus type 1 into human keratinocytes are dynamin- and cholesterol-dependent [PDF]
, 2011 Herpes simplex virus type 1 (HSV-1) can enter cells via endocytic pathways or direct fusion at the plasma membrane depending on the cell line and receptor(s).
Geraghty, R.J. +5 more
core +15 more sources
Life, 2021 Cytomegalovirus (CMV) infection initiates massive rearrangement of cytoplasmic organelles to generate assembly compartment (AC). The earliest events, the establishment of the preAC, are initiated in the early phase as an extensive reorganization of early
Igor Štimac +5 more
doaj +1 more source
Disease Models & Mechanisms, 2022 Generating reliable preclinical data in animal models of disease is essential in therapy development. Here, we performed statistical analysis and joint longitudinal–survival modeling of the progressive phenotype observed in Mtm1−/y mice, a reliable model
Suzie Buono +8 more
doaj +1 more source
CryoEM structure of the super-constricted two-start dynamin 1 filament
Nature Communications, 2021 Dynamin mediates the fission of vesicles during endocytosis. Here, the authors report the cryoEM structure of a super-constricted two-start dynamin 1 filament- one of the two known helical forms of dynamin, with insights into the molecular mechanisms of ...
Jiwei Liu +4 more
doaj +1 more source
Chemical Inhibitors of Dynamin Exert Differential Effects in VEGF Signaling
Cells, 2021 VEGFR2 is the main receptor and mediator of the vasculogenic and angiogenic activity of VEGF. Activated VEGFR2 internalizes through clathrin-mediated endocytosis and macropinocytosis.
Dimitris Basagiannis +5 more
doaj +1 more source
Cardiolipin targets a dynamin-related protein to the nuclear membrane
eLife, 2021 Dynamins are targeted to specific cellular membranes that they remodel via membrane fusion or fission. The molecular basis of conferring specificity to dynamins for their target membrane selection is not known.
Usha Pallabi Kar +2 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2022 Tilapia Lake Virus (TiLV) is an emerging virus lethal to tilapia, which threatens the global tilapia aquaculture with severe implications for food security.
Reem Abu Rass +5 more
doaj +1 more source