Results 11 to 20 of about 64,116 (254)
Gain-of-Function Properties of a Dynamin 2 Mutant Implicated in Charcot-Marie-Tooth Disease
Frontiers in Cellular Neuroscience, 2021 Mutations in the gene encoding dynamin 2 (DNM2), a GTPase that catalyzes membrane constriction and fission, are associated with two autosomal-dominant motor disorders, Charcot-Marie-Tooth disease (CMT) and centronuclear myopathy (CNM), which affect nerve
Tara C. Tassin +10 more
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Viruses, 2020 Endocytosis is a pathway used by viruses to enter cells that can be classified based on the proteins involved, such as dynamin, clathrin or caveolin. Although the entry of herpes simplex type 1 (HSV-1) by endocytosis has been documented in different cell
Beatriz Praena +2 more
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Effect of 4 Weeks of Moderate-Intensity Endurance Exercise and Lithium Administration on Blood Glucose Level in STZ-Induced Type 1 Diabetes Mellitus Mice [PDF]
운동과학, 2022 Purpose The purpose of this study was to investigate the effects of short-term endurance exercise and lithium treatment on fasting blood glucose in rats with type 1 diabetes (T1DM).
Su-Ryun Jung
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Traffic, 2006 Animal and plant cytokineses appear morphologically distinct. Recent studies, however, have revealed that these cellular processes have many things in common, including the requirement of co‐ordinated membrane trafficking and cytoskeletal dynamics. At the intersection of these two processes are the members of the dynamin family of ubiquitous eukaryotic
Catherine A, Konopka +3 more
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Current Biology, 2018 The dynamin superfamily comprises a growing assortment of multi-domain GTPases, found from bacteria to man, that are distinguished from typical GTPases of the Ras, Rab and G-protein families by their modular structure (Figure 1), relatively large size (>70 kDa), and low affinity for guanine nucleotides.
Rajesh, Ramachandran, Sandra L, Schmid
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American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023 Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei +4 more
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Mutations in human dynamin block an intermediate stage in coated vesicle formation [PDF]
, 1993 The role of human dynamin in receptor-mediated endocytosis was investigated by transient expression of GTP-binding domain mutants in mammalian cells. Using assays which detect intermediates in coated vesicle formation, the dynamin mutants were found to ...
Damke, Hanna +5 more
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eLife, 2017 Dynamin is a large GTPase that forms a helical collar at the neck of endocytic pits, and catalyzes membrane fission (Schmid and Frolov, 2011; Ferguson and De Camilli, 2012).
Valentina Galli +5 more
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Essential function of dynamin in the invasive properties and actin architecture of v-Src induced podosomes/invadosomes. [PDF]
PLoS ONE, 2013 The large GTPase dynamin plays a key role in endocytosis but is also localized at numerous actin rich sites. We investigated dynamin functions at podosomes/invadosomes, actin-based cellular adhesion structures implicated in tissue invasion.
Olivier Destaing +6 more
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Monitoring of dynamin during the Toxoplasma gondii cell cycle [PDF]
, 2016 The obligate intracellular protozoan parasite Toxoplasma gondii actively invades virtually all warm-blooded nucleated cells. This process results in a non-fusogenic vacuole, inside which the parasites replicate continuously until egress signaling is ...
Attias, Marcia +4 more
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