Results 31 to 40 of about 63,555 (261)

Role of Clathrin and Dynamin in Clathrin Mediated Endocytosis/Synaptic Vesicle Recycling and Implications in Neurological Diseases

Frontiers in Cellular Neuroscience, 2022
Endocytosis is a process essential to the health and well-being of cell. It is required for the internalisation and sorting of “cargo”—the macromolecules, proteins, receptors and lipids of cell signalling.
Kate L. Prichard, Nicholas S. O'Brien, Sari R. Murcia, Jennifer R. Baker, Adam McCluskey   +4 more
doaj   +1 more source

Dynamin Subunit Interactions Revealed [PDF]

Developmental Cell, 2010
Dynamin family members are large GTPases that assemble into multimeric spirals. These spirals promote membrane fission or fusion, or they inhibit processes such as viral replication. Two new studies by Chappie et al. and Gao et al. in a recent issue of Nature identify interactions between subunits of dynamin spirals, advancing mechanistic understanding
van der Bliek, Alexander M., Payne, Gregory S.   +1 more
openaire   +2 more sources

Ebulin l Is Internalized in Cells by Both Clathrin-Dependent and -Independent Mechanisms and Does Not Require Clathrin or Dynamin for Intoxication

Toxins, 2021
Ebulin l is an A-B toxin, and despite the presence of a B chain, this toxin displays much less toxicity to cells than the potent A-B toxin ricin. Here, we studied the binding, mechanisms of endocytosis, and intracellular pathway followed by ebulin l and ...
Rosario Iglesias, José M. Ferreras, Alicia Llorente, Lucía Citores   +3 more
doaj   +1 more source

Loss of flotillin expression results in weakened desmosomal adhesion and Pemphigus vulgaris-like localisation of desmoglein-3 in human keratinocytes [PDF]

, 2016
Desmosomes are adhesion plaques that mediate cell-cell adhesion in many tissues, including the epidermis, and generate mechanical resistance to tissues. The extracellular domains of desmosomal cadherin proteins, desmogleins and desmocollins, are required
Ali, Jawahir, Banning, Antje, Eming, Rüdiger, Exner, Yvonne, Hertl, Michael, Kurrle, Nina, Tikkanen, Ritva, Völlner, Frauke   +7 more
core   +1 more source

Dynamin-2 mutations linked to Centronuclear Myopathy impair actin-dependent trafficking in muscle cells

Scientific Reports, 2017
Dynamin-2 is a ubiquitously expressed GTP-ase that mediates membrane remodeling. Recent findings indicate that dynamin-2 also regulates actin dynamics.
Arlek M. González-Jamett, Ximena Baez-Matus, María José Olivares, Fernando Hinostroza, Maria José Guerra-Fernández, Jacqueline Vasquez-Navarrete, Mai Thao Bui, Pascale Guicheney, Norma Beatriz Romero, Jorge A. Bevilacqua, Marc Bitoun, Pablo Caviedes, Ana M. Cárdenas   +12 more
doaj   +1 more source

Dynamin recruitment by clathrin coats: a physical step? [PDF]

, 2003
Recent structural findings have shown that dynamin, a cytosol protein playing a key-role in clathrin-mediated endocytosis, inserts partly within the lipid bilayer and tends to self-assemble around lipid tubules. Taking into account these observations, we
Dommersnes, P. -G., Fournier, J. -B., Galatola, P.   +2 more
core   +2 more sources

Dynamin at actin tails [PDF]

Proceedings of the National Academy of Sciences, 2002
Dynamin, the product of the shibire gene of Drosophila, is a GTPase critically required for endocytosis. Some studies have suggested a functional link between dynamin and the actin cytoskeleton.
Eunkyung, Lee, Pietro, De Camilli
openaire   +2 more sources

The role of dynamin in absorbing lipids into endodermal epithelial cells of yolk sac membranes during embryonic development in Japanese quail

Poultry Science, 2021
: Endodermal epithelial cells (EECs) within the yolk sac membrane (YSM) of avian embryos are responsible for the absorption and utilization of lipids.
Cheng-Ting Tung, Han-Jen Lin, Chiao-Wei Lin, Harry John Mersmann, Shih-Torng Ding   +4 more
doaj   +1 more source

Dynamin- and Rab5-Dependent Endocytosis of a Ca²⁺-Activated K⁺ Channel, KCa2.3 [PDF]

, 2012
Regulation of the number of ion channels at the plasma membrane is a critical component of the physiological response. We recently demonstrated that the Ca2+-activated K+ channel, KCa2.3 is rapidly endocytosed and enters a Rab35- and EPI64C-dependent ...
Agustin Guerrero-Hernandez, Claudia A. Bertuccio, Corina M. Balut, Daniel C. Devor, Simon C. Watkins, Yajuan Gao   +5 more
core   +3 more sources

The Function of NM23-H1/NME1 and Its Homologs in Major Processes Linked to Metastasis [PDF]

, 2020
International ...
Boissan, Mathieu, Farkas, Zsolt, Kopper, László, Mehta, Anil, Mátyási, Barbara, Sebestyén, Anna, Takács-Vellai, Krisztina   +6 more
core   +4 more sources