Results 251 to 260 of about 50,252 (279)
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Negative Regulation of YY1 Transcription Factor on the Dynamin I Gene Promoter
Biochemical and Biophysical Research Communications, 2001Dynamin I is highly expressed in brain and plays a critical role in clathrin-mediated endocytosis and synaptic vesicle recycling. To elucidate the molecular mechanism by which expression of dynamin I is tissue-specifically regulated, we previously cloned and characterized the promoter of the mouse dynamin I gene and suggested that there is a negative ...
J, Yoo +6 more
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Calcineurin Inhibition of Dynamin I GTPase Activity Coupled to Nerve Terminal Depolarization
Science, 1994Dynamin I is a nerve terminal phosphoprotein with intrinsic guanosine triphosphatase (GTPase) activity that is required for endocytosis. Upon depolarization and synaptic vesicle recycling, dynamin I undergoes a rapid dephosphorylation. Dynamin I was found to be a specific high-affinity substrate for calcineurin in vitro.
J P, Liu, A T, Sim, P J, Robinson
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Age‐ and experience‐dependent expression of Dynamin I and Synaptotagmin I in cat visual system
Journal of Comparative Neurology, 2007AbstractDynamin I (Dyn I) and Synaptotagmin I (Syt I) are essential for endocytosis‐exocytosis processes, thus for neurotransmission. Despite their related function at presynaptic terminals, Dyn I and Syt I displayed opposite expression patterns during visual cortex maturation in the cat.
Lieselotte, Cnops +5 more
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Small Molecule Inhibitors of Dynamin I GTPase Activity: Development of Dimeric Tyrphostins
Journal of Medicinal Chemistry, 2005Dynamin I is a GTPase enzyme required for endocytosis and is an excellent target for the design of potential endocytosis inhibitors. Screening of a library of tyrphostins, in our laboratory, against the GTPase activity of dynamin I gave rise to a microM potent lead, 2-cyano-3-(3,4-dihydroxyphenyl)thioacrylamide (1, IC50 70 microM).
Hill, Timothy +10 more
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Case of dynamin 2 mutation‐related sporadic centronuclear myopathy with peripheral neuropathy
Neurology and Clinical Neuroscience, 2015AbstractA 53‐year‐old man presented with bilateral ptosis, diffuse muscle weakness and easy fatigability, and was admitted to Toyonaka Municipal Hospital, Osaka, Japan. The patient was diagnosed with myasthenia gravis in his childhood. Since then, he had been developing muscle weakness with atrophy.
Yuko Kawasaki +7 more
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SEARCHING FOR A PUTATIVE DYNAMIN HOMOLOGUE IN PARAMECIUM
Biochemical Society Transactions, 2000J. Wieiak, A. Platek, E. Wyroba
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Dynamin, a membrane-remodelling GTPase
Nature Reviews Molecular Cell Biology, 2012Shawn M Ferguson
exaly
The dynamin superfamily: universal membrane tubulation and fission molecules?
Nature Reviews Molecular Cell Biology, 2004Gerrit Jk Praefcke, Harvey T Mcmahon
exaly