Results 1 to 10 of about 4,214 (243)

Tracking autophagy during proliferation and differentiation of Trypanosoma brucei [PDF]

open access: yesMicrobial Cell, 2016
The dynamins represent a superfamily of proteins that have been shown to function in a wide range of membrane fusion and fission events. An increasing number of mutations in the human classical dynamins, Dyn-1 and Dyn-2 has been reported, with diseases ...
Laila Moustaq   +4 more
doaj   +6 more sources

Mesoscopic elasticity controls dynamin-driven fission of lipid tubules [PDF]

open access: yesScientific Reports
Mesoscale physics bridges the gap between the microscopic degrees of freedom of a system and its large-scale continuous behavior and highlights the role of a few key quantities in complex and multiscale phenomena, like dynamin-driven fission of lipid ...
Marco Bussoletti   +4 more
doaj   +2 more sources

The dynamin-related protein PfDyn2 is essential for both apicoplast and mitochondrial fission in Plasmodium falciparum [PDF]

open access: yesmBio
Dynamins, or dynamin-related proteins (DRPs), are large mechano-sensitive GTPases that mediate membrane dynamics or organellar fission/fusion events. Plasmodium falciparum encodes three dynamin-like proteins whose functions are poorly understood.
Alexander A. Morano   +5 more
doaj   +2 more sources

Organelle Dynamics in Apicomplexan Parasites

open access: yesmBio, 2021
Apicomplexan parasites, such as Toxoplasma gondii and Plasmodium falciparum, are the cause of many important human and animal diseases. While T. gondii tachyzoites replicate through endodyogeny, during which two daughter cells are formed within the ...
Julie M. J. Verhoef   +2 more
doaj   +1 more source

Filamentous actin destabilization by H2O2 favors DnmA aggregation, with crucial roles of cysteines 450 and 776 in mitochondrial and peroxisomal division in Aspergillus nidulans

open access: yesmBio, 2023
The dynamin-like protein DnmA and its receptor FisA are essential for mitochondrial division in the fungus Aspergillus nidulans. Our research has demonstrated that H2O2 triggers significant changes in mitochondrial morphology, including constriction ...
Verónica Garrido-Bazán   +3 more
doaj   +1 more source

Arabidopsis Dynamin-Related Protein AtDRP2A Contributes to Late Flg22-Signaling and Effective Immunity Against Pseudomonas syringae Bacteria

open access: yesMolecular Plant-Microbe Interactions, 2023
In eukaryotes, dynamins and dynamin-related proteins (DRPs) are high–molecular weight GTPases responsible for mechanochemical fission of organelles or membranes.
Gayani Ekanayake   +3 more
doaj   +1 more source

Cardiolipin targets a dynamin-related protein to the nuclear membrane

open access: yeseLife, 2021
Dynamins are targeted to specific cellular membranes that they remodel via membrane fusion or fission. The molecular basis of conferring specificity to dynamins for their target membrane selection is not known.
Usha Pallabi Kar   +2 more
doaj   +1 more source

Changes of different connexins and mitochondrial dynamins in early acute kidney injury after liver transplantation [PDF]

open access: yesXin yixue, 2023
Objective To explore the potential relationship between different connexins and mitochondrial dynamic imbalance and mitochondrial injury in early acute kidney injury after liver transplantation.
Mai Kangfeng, Li Jiaai, Wei Jingru, Chen Chaojin, Li Xiaoyun
doaj   +1 more source

Role of GTPase-Dependent Mitochondrial Dynamins in Heart Diseases

open access: yesFrontiers in Cardiovascular Medicine, 2021
Heart function maintenance requires a large amount of energy, which is supplied by the mitochondria. In addition to providing energy to cardiomyocytes, mitochondria also play an important role in maintaining cell function and homeostasis.
Jiangen Liu   +3 more
doaj   +1 more source

TMEM16F and dynamins control expansive plasma membrane reservoirs

open access: yesNature Communications, 2021
Cells locally expand and retract their surface in response to environmental factors such as changes in membrane tension. Here the authors show the membrane adapter, dynamin2, locally constricts surface membrane to form an isolated but contiguous membrane
Christine Deisl   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy