RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease
Hepatology, EarlyView., 2022 RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso +16 more
wiley +1 more source
The role of clathrin in post-golgi trafficking in toxoplasma gondii [PDF]
, 2013 Apicomplexan parasites are single eukaryotic cells with a highly polarised secretory system that contains unique secretory organelles (micronemes and rhoptries) that are required for host cell invasion.
Ferguson, D.J.P. +3 more
core +8 more sources
A proteomic study of memory after imprinting in the domestic chick
Frontiers in Behavioral Neuroscience, 2015 The intermediate and medial mesopallium (IMM) of the domestic chick forebrain has previously been shown to be a memory system for visual imprinting. Learning-related changes occur in certain plasma membrane and mitochondrial proteins in the IMM.
Maia eMeparishvili +6 more
doaj +1 more source
Dynamin-like proteins in Trypanosoma brucei: A division of labour between two paralogs? [PDF]
PLoS ONE, 2017 Dynamins and dynamin-like proteins (DLPs) belong to a family of large GTPases involved in membrane remodelling events. These include both fusion and fission processes with different dynamin proteins often having a specialised function within the same ...
Corinna Benz +3 more
doaj +1 more source
Virtual Screening and Hit Selection of Natural Compounds as Acetylcholinesterase Inhibitors
Molecules, 2022 Acetylcholinesterase (AChE) is one of the classical targets in the treatment of Alzheimer’s disease (AD). Inhibition of AChE slows down the hydrolysis of acetycholine and increases choline levels, improving the cognitive function. The achieved success of
Mariyana Atanasova +6 more
doaj +1 more source
mBio, 2022 Bacillus subtilis DynA is a member of the dynamin superfamily, involved in membrane remodeling processes. DynA was shown to catalyze full membrane fusion and it plays a role in membrane surveillance against antibiotics.
Lijun Guo +4 more
doaj +1 more source
Dynamins maintain nuclear envelope homeostasis and genome stability
Nature CommunicationsThe nuclear envelope is a protective barrier for the genome and a mechanotransduction interface between cytoplasm and nucleus, whose malfunction disrupts nucleocytoplasmic transport, compromises DNA repair, accelerates telomere shortening, and promotes ...
Célia Aveleira +13 more
doaj +1 more source
Dynamin-Like Protein B of Dictyostelium Contributes to Cytokinesis Cooperatively with Other Dynamins
Cells, 2019 Dynamin is a large GTPase responsible for diverse cellular processes, such as endocytosis, division of organelles, and cytokinesis. The social amoebozoan, Dictyostelium discoideum, has five dynamin-like proteins: dymA, dymB, dlpA, dlpB, and dlpC.
Koushiro Fujimoto +8 more
doaj +1 more source
Identification of novel NPRAP/δ-catenin-interacting proteins and the direct association of NPRAP with dynamin 2. [PDF]
PLoS ONE, 2011 Neural plakophilin-related armadillo protein (NPRAP or δ-catenin) is a neuronal-specific protein that is best known for its interaction with presenilin 1 (PS1).
Carolina Koutras, Georges Lévesque
doaj +1 more source
Open and cut: allosteric motion and membrane fission by dynamin superfamily proteins. [PDF]
, 2019 Cells have evolved diverse protein-based machinery to reshape, cut, or fuse their membrane-delimited compartments. Dynamin superfamily proteins are principal components of this machinery and use their ability to hydrolyze GTP and to polymerize into ...
Frost, Adam, Kalia, Raghav
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