Molecular Aspect of Annelid Neuroendocrine system
, 2007 Hormonal processes along with enzymatic processing similar to that found in vertebrates occur in annelids. Amino acid sequence determination of annelids precursor gene products reveals the presence of the respective peptides that exhibit high sequence ...
Salzet, M.
core +1 more source
Pathology and glia type specific changes of the DPP4 activity in the spinal cord contributes to the development and maintenance of hyperalgesia and shapes opioid signalling in chronic pain states [PDF]
, 2017 Altered pain sensations such as hyperalgesia and allodynia are characteristic features of various chronic pain states, and remain difficult to treat.
Alpár, Alán +14 more
core
A standardized transcutaneous electric acupoint stimulation for relieving tobacco urges in dependent smokers [PDF]
, 2008 The efficacy of acupuncture in smoking cessation, and its effect on the urge to smoke are unclear. We evaluated the effect of a standardized protocol of transcutaneous electric acupoint stimulations (TEAS) on alleviating the urge to smoke.
Berlin, Ivan +6 more
core +1 more source
A Biological Model of Acupuncture and its Derived Mathematical Modeling and Simulations [PDF]
, 2015 International audience(Aims) Acupuncture was employed since 2 millenaries, but the underlying mechanisms are not globally handled. The present study is aimed at proposing an explanation by pointing out involved processes and a convincing modeling to ...
Deleuze, Yannick +2 more
core +4 more sources
Switching to low-dose oral prolonged-release oxycodone/naloxone from WHO-step i drugs in elderly patients with chronic pain at high risk of early opioid discontinuation [PDF]
, 2016 Chronic pain has a high prevalence in the aging population. Strong opioids also should be considered in older people for the treatment of moderate to severe pain or for pain that impairs functioning and the quality of life. This study aimed to assess the
Caldarulo, C +6 more
core +2 more sources
Individual differences in the neuropsychopathology of addiction. [PDF]
, 2017 Drug addiction or substance-use disorder is a chronically relapsing disorder that progresses through binge/intoxication, withdrawal/negative affect and preoccupation/anticipation stages.
George, Olivier, Koob, George F
core
Kappa opioid receptor and dynorphin signaling in the central amygdala regulates alcohol intake
, 2020 Daniel W. Bloodgood +9 more
openalex +2 more sources
Dynorphin opioids present in dentate granule cells may function as retrograde inhibitory neurotransmitters [PDF]
, 1994 CT Drake +6 more
openalex +1 more source
Endorphins, Exercise, and Addictions: A Review of Exercise Dependence [PDF]
, 2006 Endorphins are endogenous opioids released from the pituitary gland that are believed to mediate analgesia, induce euphoria, and play a role in the reward system in the brain. It has been suggested that endorphins are responsible for creating the relaxed
Andrea Leuenberger
core