Results 81 to 90 of about 3,745 (209)
VIEW, Volume 7, Issue 2, April 2026.Acupuncture anesthesia (AA) is an application of acupuncture innovation in surgical operations, combined with anesthetic techniques, and is a model of integrated Chinese and Western medicine. We proposed the Acupuncture Anesthesia Knowledge Database (AAKD), in which all data have been meticulously curated by field experts and assessed by a multi ...
Ying Wang +11 more
wiley +1 more source
Role of Opioid Ligands in the Irritable Bowel Syndrome
Canadian Journal of Gastroenterology, 1999 Endogenous opioid peptides – enkephalins, beta-endorphin and dynorphins – are located in specific sites of the brain, the spinal cord, the autonomic ganglia and the enteric nervous system.
Enrico Corazziari
doaj +1 more source
Pathology and glia type specific changes of the DPP4 activity in the spinal cord contributes to the development and maintenance of hyperalgesia and shapes opioid signalling in chronic pain states [PDF]
, 2017 Altered pain sensations such as hyperalgesia and allodynia are characteristic features of various chronic pain states, and remain difficult to treat.
Alpár, Alán +14 more
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Acupuncture analgesia for temporal summation of experimental pain: A randomised controlled study [PDF]
, 2010 Background: Temporal summation of pain, a phenomenon of the central nervous system (CNS), represents enhanced painful sensation or reduced pain threshold upon repeated stimulation. This pain model has been used to evaluate the analgesic effect of various
Da Costa, C +5 more
core +1 more source
Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 4, Page 568-574, April 2026.It is expected that the relugolix estetrol combination RE4W will enable women to control their fertility and prevent menstrual cycle related problems, while offering a smooth transition through perimenopause into the postmenopause and decrease the risk of breast cancer.
Herjan J. T. Coelingh Bennink +9 more
wiley +1 more source
British Journal of Pharmacology, Volume 183, Issue 7, Page 1313-1340, April 2026.Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang +18 more
wiley +1 more source
A Theory of Natural Addiction [PDF]
Economic theories of rational addiction aim to describe consumer behavior in the presence of habit-forming goods. We provide a biological foundation for this body of work by formally specifying conditions under which it is optimal to form a habit.
Attila Tasnádi, Trenton G. Smith
core +3 more sources
Endorphins, Exercise, and Addictions: A Review of Exercise Dependence [PDF]
, 2006 Endorphins are endogenous opioids released from the pituitary gland that are believed to mediate analgesia, induce euphoria, and play a role in the reward system in the brain. It has been suggested that endorphins are responsible for creating the relaxed
Andrea Leuenberger
core
Synthesis of a novel universal opioid receptor agonist with the 1,3,5-trioxazatriquinane skeleton and its pharmacologies [PDF]
, 2014 We designed and synthesized of 1,3,5-trioxazatriquinanes with o- or p-hydroxyphenyl rings as analogs of the κ opioid receptor agonist SYK-146 with m-hydroxyphenyl groups. Although almost all tested compounds did not bind to the opioid receptors, only 17b
Fujii Hideaki +8 more
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Kinin B(1) receptor deficiency leads to leptin hypersensitivity and resistance to obesity [PDF]
, 2008 OBJECTIVE-Kinins mediate pathophysiological processes related to hypertension, pain, and inflammation through the activation of two G-protein-coupled receptors, named B(1) and B(2).
Araujo, Ronaldo de Carvalho +19 more
core +3 more sources