Results 81 to 90 of about 2,342 (192)

Big dynorphin as a putative endogenous ligand for the κ‐opioid receptor

, 2006
International audienceThe diversity of peptide ligands for a particular receptor may provide a greater dynamic range of functional responses, while maintaining selectivity in receptor activation.
Brigitte L. Kieffer, Bark, Niklas, Niklas Bark, Filliol, Dominique, Kieffer, Brigitte L, Bakalkin, Georgy, Igor Bazov, Merg, Florence, Hurd, Yasmin L, Bazov, Igor, Florence Merg, Dominique Filliol, Tatjana Yakovleva, Yakovleva, Tatjana, Yasmin L. Hurd, Usynin, Ivan, Georgy Bakalkin, Ivan Usynin   +17 more
core   +2 more sources

Dynorphin: friend or foe?

Pain, 2000
Pain 87 (2000) 235-239. doi:10.1016/S0304-3959(00)00360-2 ; Received by publisher: 2000-05-22 ; Harvest Date: 2016-01-04 12:22:07 ; DOI:10.1016/S0304-3959(00)00360-2 ; Page Range: 235 ...
Department of Oral Surgery, Division of Neuroscience, University of Florida College of Dentistry, P.O. Box 100416, Gainesville, FL 32610, USA ( host institution ), Caudle, Robert M. ( author ), Mannes, Andrew J. ( author )   +2 more
openaire   +3 more sources

Presentation_1_Cellular Profiles of Prodynorphin and Preproenkephalin mRNA-Expressing Neurons in the Anterior Olfactory Tubercle of Mice.PDF

, 2022
The olfactory tubercle (OT) is a striatal region that receives olfactory inputs. mRNAs of prodynorphin (Pdyn) and preproenkephalin (Penk), precursors of dynorphins and enkephalins, respectively, are strongly expressed in the striatum. Both produce opioid
Shigeharu Fujieda (188194), Yugo Fukazawa (180184), Koshi Murata (11584171), Ayako Maegawa (13134600), Kazuki Kuroda (3778783)   +4 more
core   +1 more source

From dysphoria to depression. The role of dynorphins and kappa opioid receptors in the pathophysiology of stress related disorders

, 2013
Stres jest złożonym zjawiskiem, które wywiera wpływ na zdrowie i funkcjonowanie jednostki. Dynorfiny i receptory opioidowe kappa stanowią część endogennego systemu, który kontroluje homeostazę organizmu.
Cieślak, Przemysław
core  

Calcium influx into phospholipid vesicles caused by dynorphin neuropeptides

, 2008
Dynorphins, endogeneous opioid peptides, function as ligands to the opioid kappa receptors but also induce non-opioid excitotoxic effects. Dynorphin A can increase the intra-neuronal calcium concentration through a non-opioid and non-NMDA mechanism.
Hugonin, L, Bakalkin, G, Gräslund, Astrid, Gräslund, Astrid,, Hugonin, Loïc, Hugonin, Loïc,, Graslund, A, Vukojević, Vladana, Bakalkin, Georgy,, Bakalkin, Georgy, Vukojevic, V,   +10 more
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Secondary structure transitions and aggregation induced in dynorphin neuropeptides by the detergent sodium dodecyl sulfate

, 2008
Dynorphins, endogeneous opioid neuropeptides, function as ligands to the opioid kappa receptors and also induce non-opioid effects in neurons, probably related to direct membrane interactions. We have characterized the structure transitions of dynorphins
Perálvarez-Marín, Alex,, Barth, Andreas,, Gräslund, Astrid,, Hugonin, Loïc,   +3 more
core   +2 more sources

Prodynorphin-Derived Opioid Peptides

, 2006
The dynorphin family is composed of multiple peptides. They are distributed in the central nervous system and peripheral tissues. Dynorphins dusply several biological functions, including the regulation of pain transmission, feeding, pituitary hormone ...
SPAMPINATO, SANTI MARIO, SANTI SPAMPINATO   +1 more
core   +1 more source

Mobilization of Specific Neuropeptides by Peripheral Stimulation of Identified Frequencies

, 1992
Three families of endogenous opioid peptides have been characterized in the CNS: enkephalins, endorphins and dynorphins. These can be mobilized by peripheral electrical stimulation.
Q Wang, J-S Han
core   +1 more source

Characterization of the opioid receptor type mediating inhibition of rat gastric somatostatin secretion

, 1990
The opioid peptides are potent inhibitors of gastric somatostatin-like immunoreactivity (SLI) secretion from the isolated perfused rat stomach. In addition, inhibition of SLI secretion induced by vagal stimulation is partially blocked by naloxone ...
C. H. McIntosh, Y. N. Kowk, X. Jia
core   +1 more source

L-DOPA-induced dyskinesia is associated with regional increase of striatal dynorphin peptides as elucidated by imaging mass spectrometry

, 2011
Opioid peptides are involved in various pathophysiological processes, including algesia, epilepsy and drug dependency. A strong association between L-DOPA-induced dyskinesia (LID) and elevated prodynorphin mRNA levels has been established in both ...
F\ue4lth, Maria, Ljungdahl, Anna, Mammo, Sofie Eriksson, Malin Andersson, Andersson, Malin, Sofie Eriksson Mammo, Eriksson Mammo, Sofie, Eriksson Mammo, Sofie,, Hanrieder, Jörg, Bergquist, Jonas, Jörg Hanrieder, Hanrieder, J\uf6rg, Anna Ljungdahl, Hanrieder, Jörg,, Fälth, Maria, Ljungdahl, Anna,, Maria Fälth, Andersson, Malin,, Jonas Bergquist, Bergquist, Jonas,   +19 more
core   +1 more source