Results 41 to 50 of about 1,167,163 (294)

Early Life Stress, Hormones, and Neurodevelopmental Disorders

Hormone Research in Paediatrics, 2022
Background: Early life stress (ELS) describes a broad spectrum of adverse and stressful prenatal events, namely, prenatal maternal stress (PMS), or early postnatal events, which can have detrimental long-term influences on the physiology, cognition, and behavior of an individual. There is abundant evidence indicating that ELS exerts its lasting effects
Gerasimos Makris, Anna Eleftheriades, Panagiota Pervanidou   +2 more
openaire   +3 more sources

Early Life Stress, Nicotinic Acetylcholine Receptors and Alcohol Use Disorders

, 2015
Stress is a major driving force in alcohol use disorders (AUDs). It influences how much one consumes, craving intensity and whether an abstinent individual will return to harmful alcohol consumption. We are most vulnerable to the effects of stress during
Selena E. Bartlett, Joan Holgate, Selena Bartlett, Bartlett, Selena E., Holgate, Joan Y., Joan Y. Holgate   +5 more
core   +1 more source

Stress in healthy young women : psychophysiological stress response and sleep in the context of adverse childhood experiences and daily stress [PDF]

, 2014
The aim of the present dissertation is to contribute to the knowledge about different aspects of stress and their impact on healthy young women. The relationship between daily stress, presleep arousal, and sleep was investigated and additionally, the ...
Winzeler, Katja
core   +1 more source

Neurobiology of Maternal Stress: Role of Social Rank and Central Oxytocin in Hypothalamic-Pituitary Adrenal Axis Modulation

Frontiers in Psychiatry, 2015
Background: Chronic stress may conceivably require plasticity of maternal physiology and behavior to cope with the conflicting primary demands of infant rearing and foraging for food.
Jeremy D Coplan, Asif eKarim, Prakash eChandra, Garleen eSt. Germain, Chadi G Abdallah, Margaret eAltemus   +5 more
doaj   +1 more source

Perceived control, loneliness, early-life stress, and parents’ perceptions of stress

Scientific Reports, 2023
The COVID-19 pandemic has highlighted the importance of understanding what contributes to individual variability in experiences of stress. Increases in stress related to the pandemic have been especially pronounced in parents, indicating a need for ...
Karen E. Smith, Eileen Graf, Kelly E. Faig, Stephanie J. Dimitroff, Frederica Rockwood, Marc W. Hernandez, Greg J. Norman   +6 more
doaj   +1 more source

Dysregulation of the mesoprefrontal dopamine circuit mediates an early-life stress-induced synaptic imbalance in the prefrontal cortex

Cell Reports, 2021
Summary: Stress adversely affects an array of cognitive functions. Although stress-related disorders are often addressed in adulthood, far less is known about how early-life stress (ELS) affects the developing brain in early postnatal periods.
Won Chan Oh, Gabriela Rodríguez, Douglas Asede, Kanghoon Jung, In-Wook Hwang, Roberto Ogelman, McLean M. Bolton, Hyung-Bae Kwon   +7 more
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Insecure attachment during infancy predicts greater amygdala volumes in early adulthood [PDF]

, 2014
Background The quality of the early environment is hypothesized to be an influence on morphological development in key neural areas related to affective responding, but direct evidence to support this possibility is limited.
Pliatsikas, C., Johnstone, Tom, Halligan, S.L., Moutsiana, C., Goodyer, I., Goodyer, Ian, Moutsiana, Christina, Murray, Lynne, Halligan, Sarah L., Cooper, Peter J., Johnstone, T., Fearon, P., Cooper, P.J., Murray, L., Fearon, Pasco, Pliatsikas, Christos   +15 more
core   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Cortisol diurnal rhythm and stress reactivity in male adolescents with early-onset or adolescence-onset conduct disorder [PDF]

, 2008
Background: Previous studies have reported lower basal cortisol levels and reduced cortisol responses to stress in children and adolescents with conduct disorder (CD). It is not known whether these findings are specific to early-onset CD.
Stephanie H.M. van Goozen, Sarah J. Stollery, Gardiner, Julian, van Goozen, Stephanie HM, van Goozen, Stephanie H.M., Van Goozen, Stephanie Helena Maria, Graeme Fairchild, Stollery, Sarah J., Goodyer, Ian M, Herbert, Joe, Stollery, Sarah J, Brown, Jamie, Goodyer, Ian M., Goodyer, Ian M., Ian M. Goodyer, Julian Gardiner, Stollery, Sarah J.., Joe Herbert, Jamie Brown, Fairchild, Graeme   +19 more
core   +1 more source