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Ebolavirus evolution and emergence are associated with land use change
Ecological Monographs, Volume 95, Issue 1, February 2025.Anthropogenic land use change facilitates disease emergence by altering the interface between humans and pathogen reservoirs and is hypothesized to drive pathogen evolution.
Christian E. Lange +8 more
semanticscholar +3 more sources
Ebolavirus replication and Tetherin/BST-2 [PDF]
Frontiers in Microbiology, 2012 Ebolavirus (EBOV) is an enveloped, non-segmented, negative-stranded RNA virus, which consists of five species: Zaire ebolavirus (ZEBOV), Sudan ebolavirus (SEBOV), Tai Forest ebolavirus (TFEBOV), Bundibugyo ebolavirus (BEBOV), and Reston ebolavirus (REBOV)
Jiro eYasuda
doaj +2 more sources
Pathogens, 2022 Intravenous (IV) administration of antiviral monoclonal antibodies (mAbs) can be challenging, particularly during an ongoing epidemic, due to the considerable resources required for performing infusions.
Erin Kuang +17 more
doaj +2 more sources
PLoS Neglected Tropical Diseases, 2022 Although multiple antigenically distinct ebolavirus species can cause human disease, previous serosurveys focused on only Zaire ebolavirus (EBOV). Thus, the extent of reactivity or exposure to other ebolaviruses, and which sociodemographic factors are ...
Kelly C L Shaffer +18 more
doaj +2 more sources
Newly discovered ebola virus associated with hemorrhagic fever outbreak in Uganda. [PDF]
PLoS Pathogens, 2008 Over the past 30 years, Zaire and Sudan ebolaviruses have been responsible for large hemorrhagic fever (HF) outbreaks with case fatalities ranging from 53% to 90%, while a third species, Côte d'Ivoire ebolavirus, caused a single non-fatal HF case.
Jonathan S Towner +17 more
doaj +5 more sources
Fruit–frugivore dependencies are important in Ebolavirus outbreaks in Sub-Saharan Africa
Ecography, Volume 2024, Issue 10, October 2024.Ebolaviruses have the ability to infect a wide variety of species, with many African mammals potentially serving either as primary reservoirs or secondary amplifying hosts.
Mekala Sundaram +8 more
semanticscholar +2 more sources
Frontiers in Immunology, 2022 Monoclonal antibodies (mAbs) have proven effective for the treatment of ebolavirus infection in humans, with two mAb-based drugs Inmazeb™ and Ebanga™ receiving FDA approval in 2020.
Charles D. Murin +5 more
doaj +2 more sources
Ebolavirus diagnosis made simple, comparable and faster than molecular detection methods: preparing for the future [PDF]
Virology Journal, 2018 Background The 2014/2015 Ebolavirus outbreak resulted in more than 28,000 cases and 11,323 reported deaths, as of March 2016. Domestic transmission of the Guinea strain associated with the outbreak occurred mainly in six African countries, and ...
Ameh S. James +4 more
doaj +2 more sources
Traits, phylogeny and host cell receptors predict Ebolavirus host status among African mammals.
PLoS Neglected Tropical Diseases, 2022 We explore how animal host traits, phylogenetic identity and cell receptor sequences relate to infection status and mortality from ebolaviruses. We gathered exhaustive databases of mortality from Ebolavirus after exposure and infection status based on ...
Mekala Sundaram +4 more
doaj +2 more sources
Bombali Ebolavirus in Mops condylurus Bats (Molossidae), Mozambique
Emerging Infectious Diseases, 2022 We detected Bombali ebolavirus RNA in 3 free-tailed bats (Mops condylurus, Molossidae) in Mozambique. Sequencing of the large protein gene revealed 98% identity with viruses previously detected in Sierra Leone, Kenya, and Guinea.
Camille Lebarbenchon +9 more
doaj +2 more sources