Data from: A systematic review and meta-analysis of seroprevalence surveys of ebolavirus infection [PDF]
, 2017 The dataset contains findings and information from 51 seroprevelance studies performed from on samples collected from 1961 to 2016. These investigated 84 exposure-defined subgroups of subjects reported to have had no symptoms of EVD during the outbreak ...
Bower, Hilary, Glynn, Judith
core +4 more sources
Newly discovered ebola virus associated with hemorrhagic fever outbreak in Uganda. [PDF]
PLoS Pathogens, 2008 Over the past 30 years, Zaire and Sudan ebolaviruses have been responsible for large hemorrhagic fever (HF) outbreaks with case fatalities ranging from 53% to 90%, while a third species, Côte d'Ivoire ebolavirus, caused a single non-fatal HF case.
Jonathan S Towner +17 more
doaj +5 more sources
Cryo-EM structure of Sudan ebolavirus glycoprotein complexed with its human endosomal receptor NPC1 [PDF]
Communications BiologySudan ebolavirus (SUDV), like Ebola ebolavirus (EBOV), poses a significant threat to global health and security due to its high lethality. However, unlike EBOV, there are no approved vaccines or treatments for SUDV, and its structural interaction with ...
Fan Bu +5 more
doaj +2 more sources
Filovirus RefSeq Entries: Evaluation and Selection of Filovirus Type Variants, Type Sequences, and Names [PDF]
Viruses, 2014 Sequence determination of complete or coding-complete genomes of viruses is becoming common practice for supporting the work of epidemiologists, ecologists, virologists, and taxonomists.
Jens H. Kuhn +75 more
doaj +5 more sources
Testing New Hypotheses Regarding Ebolavirus Reservoirs [PDF]
Viruses, 2016 Despite a relatively long search for the origin of ebolaviruses, their reservoirs remain elusive. Researchers might have to consider testing alternative hypotheses about how these viruses persist and emerge to advance ebolavirus research.
Siv Aina Jensen Leendertz
doaj +2 more sources
In Silico Identification of Antiviral Peptides as Potential Leads Against Sudan Ebolavirus VP-40. [PDF]
Biomed Res IntOmara B +12 more
europepmc +3 more sources
Ebola virus matrix protein VP40 triggers inflammatory responses linked to the ebolavirus virulence. [PDF]
Proc Natl Acad Sci U S AYamaoka S +12 more
europepmc +3 more sources
Frontiers in Immunology, 2022 Monoclonal antibodies (mAbs) have proven effective for the treatment of ebolavirus infection in humans, with two mAb-based drugs Inmazeb™ and Ebanga™ receiving FDA approval in 2020.
Charles D. Murin +5 more
doaj +1 more source
Ebolavirus is internalized into host cells via macropinocytosis in a viral glycoprotein-dependent manner. [PDF]
PLoS Pathogens, 2010 Ebolavirus (EBOV) is an enveloped, single-stranded, negative-sense RNA virus that causes severe hemorrhagic fever with mortality rates of up to 90% in humans and nonhuman primates.
Asuka Nanbo +7 more
doaj +1 more source
Ebolaviruses: New roles for old proteins. [PDF]
PLoS Neglected Tropical Diseases, 2018 In 2014, the world witnessed the largest Ebolavirus outbreak in recorded history. The subsequent humanitarian effort spurred extensive research, significantly enhancing our understanding of ebolavirus replication and pathogenicity.
Diego Cantoni, Jeremy S Rossman
doaj +1 more source