Results 101 to 110 of about 12,943 (270)

First laboratory confirmation and sequencing of Zaire ebolavirus in Uganda following two independent introductions of cases from the 10th Ebola Outbreak in the Democratic Republic of the Congo, June 2019

PLoS Neglected Tropical Diseases, 2022
Uganda established a domestic Viral Hemorrhagic Fever (VHF) testing capacity in 2010 in response to the increasing occurrence of filovirus outbreaks.
L. Nyakarahuka, S. Mulei, S. Whitmer, Kyondo Jackson, A. Tumusiime, A. Schuh, J. Baluku, Allison Joyce, F. Ocom, J. Tusiime, J. Montgomery, S. Balinandi, J. Lutwama, J. Klena, T. Shoemaker   +14 more
semanticscholar   +1 more source

Antiviral therapies against Ebola and other emerging viral diseases using existing medicines that block virus entry [PDF]

, 2015
Emerging viral diseases pose a threat to the global population as intervention strategies are mainly limited to basic containment due to the lack of efficacious and approved vaccines and antiviral drugs.
A De Milito, A De Milito, A Freiberg, A Gulland, A Marzi, A Sheraly, A Yoshimura, B Bishop, B Elander, B Salvador, D Gatherer, D Vigerust, E Fellenius, E Ooi, E Wright, F Luciani, F Perut, F Turone, G Gehring, H Feldmann, H Kibuuka, J Kouznetsova, J Lalezari, J Ledgerwood, J Long, J Nuckols, J Pallister, J Tuukkanen, K Chandran, K Gnirss, K Maitland, K Mizunashi, K Mupapa, K Müller, K Saliba, K Schornberg, L Oestereich, M Brecher, M Rutz, N Paton, N Temperton, N White, O Hart, O Moncorgé, P Jahrling, P Madrid, R Dean, R Gasparini, R Kanapathipillai, R Wool-Lewis, S Avnet, S Baize, S Chikte, S Ekins, S Mather, S Smither, T Burnouf, T Lind, T Nagata, T Shintani, V Sandrin, V Tricou, W Howard, X De Lamballerie, X Qiu, Y Li   +65 more
core   +4 more sources

Land Use Change and Infectious Disease Emergence

Reviews of Geophysics, Volume 63, Issue 2, June 2025.
Abstract Major infectious diseases threatening human health are transmitted to people from animals or by arthropod vectors such as insects. In recent decades, disease outbreaks have become more common, especially in tropical regions, including new and emerging infections that were previously undetected or unknown. Even though there is growing awareness
M. Cristina Rulli, Paolo D’Odorico, Nikolas Galli, Reju S. John, Renata L. Muylaert, Monia Santini, David T. S. Hayman   +6 more
wiley   +1 more source

Ebola Haemorrhagic Fever in Africa: a Necessary Highlight [PDF]

, 2019
The purpose of this commentary is to re-evaluate the historic and scientific facts on Ebola haemorrhagic fever and the role of the International community, especially Economic Community of West African States (ECOWAS) in stemming the tide.
Adu-Gyamfi, S. (Samuel)
core   +3 more sources

Process Intensification for Recombinant Marburg Virus Glycoprotein Production Using Drosophila S2 Cells

Engineering in Life Sciences, Volume 25, Issue 5, May 2025.
ABSTRACT Marburg marburgvirus (MARV) is a highly virulent human pathogen with limited therapeutic options. Recombinant MARV glycoprotein (GP) produced in Drosophila Schneider 2 (S2) cells has been extensively investigated as potential vaccine antigen with promising efficacy demonstrated in nonhuman primate models.
Sven Göbel, Ludwig Mayerlen, Isabelle Yazel Eiser, Lisa Fichtmueller, David Clements, Udo Reichl, Yvonne Genzel, AxelT. Lehrer   +7 more
wiley   +1 more source

Comparative Analysis of the Sequenced Zaire ebolavirus Samples from the Republic of Guinea

Проблемы особо опасных инфекций, 2015
An unprecedented on its scale Ebola fever epidemic, caused by Zaire ebolavirus, has been registered in the territory of West Africa in 2014-2015. The virus quickly spread from the Republic of Guinea into the neighboring countries.
Ya. M. Krasnov, V. A. Safronov, N. Yu. Nosov, V. V. Kutyrev, A. Yu. Popova   +4 more
doaj   +1 more source

Lessons Learned from the Development and Roll-Out of the rVSVΔG-ZEBOV-GP Zaire ebolavirus Vaccine to Inform Marburg Virus and Sudan ebolavirus Vaccines

Vaccines, 2022
This review describes key aspects of the development of the rVSVΔG-ZEBOV-GP Ebola vaccine and key activities which are continuing to further expand our knowledge of the product.
B. Coller, W. Lapps, Mahum Yunus, S. Bruno, M. Eichberg, A. Lee, Ken Liu, R. Drury, J. Millogo, L. Macareo, Thomas H. Armstrong, J. Blue, L. Isopi, Melissa Hughes, Susan M. VanRheenen, Jonathan Deutsch, J. Tell, S. Dubey   +17 more
semanticscholar   +1 more source

Marburg Virus Disease: A Narrative Review

Health Science Reports, Volume 8, Issue 5, May 2025.
ABSTRACT Background and Aims Given the recent deadly outbreaks of the Marburg virus (MARV), in early 2023 in Tanzania and Equatorial Guinea, and the most recent one in Rwanda in 2024, there has been renewed attention across Africa on the threat posed by the re‐emergence of MARV as a growing concern for public health.
Arash Letafati, Somayeh Sadat Hosseini Fakhr, Ali Qaraee Najafabadi, Negin Karami, Hassan Karami   +4 more
wiley   +1 more source

Ebola virus disease: past, present and future

Asian Pacific Journal of Tropical Biomedicine, 2015
Ebola virus disease is one of the most deadly ailments known to mankind due to its high mortality rate (up to 90%) accompanying with the disease. Ebola haemorrhagic fever (EHF) is an infectious disease of animal that can be transmitted to both human and ...
Harish Rajak, Deepak Kumar Jain, Avineesh Singh, Ajay Kumar Sharma, Anshuman Dixit   +4 more
doaj   +1 more source

A broadly-neutralizing antibody againstEbolavirusglycoprotein that potentiates the breadth and neutralization potency of other antibodies

bioRxiv
Ebolavirus disease (EVD) is caused by multiple species of Ebolavirus. Monoclonal antibodies (mAbs) against the virus glycoprotein (GP) are the only class of therapeutic approved for treatment of EVD caused by Zaire ebolavirus (EBOV).
Donnellan FR, Rayaprolu V, Rijal P, O’Dowd V, Parvate A, Callaway H, Hariharan C, Parekh D, Hui S, Shaffer K, Avalos RD, Hastie K, Schimanski L, Müller-Kräuter H, Strecker T, Balaram A, Halfmann P, Saphire EO, Lightwood DJ, Townsend AR, Draper SJ.   +20 more
europepmc   +2 more sources