Results 101 to 110 of about 12,924 (266)

A comprehensive overview on the crosstalk between microRNAs and viral pathogenesis and infection

Medicinal Research Reviews, Volume 45, Issue 2, Page 349-425, March 2025.
Abstract Infections caused by viruses as the smallest infectious agents, pose a major threat to global public health. Viral infections utilize different host mechanisms to facilitate their own propagation and pathogenesis. MicroRNAs (miRNAs), as small noncoding RNA molecules, play important regulatory roles in different diseases, including viral ...
Seyedeh Zahra Bahojb Mahdavi, Asiyeh Jebelli, Parisa Shiri Aghbash, Behzad Baradaran, Mohammad Amini, Fatemeh Oroojalian, Nasser Pouladi, Hossein Bannazadeh Baghi, Miguel de la Guardia, Amir Ali Mokhtarzadeh   +9 more
wiley   +1 more source

Taï Forest Virus Does Not Cause Lethal Disease in Ferrets

Microorganisms, 2021
Filoviruses are zoonotic, negative-sense RNA viruses, most of which are capable of causing severe disease in humans and nonhuman primates, often with high case fatality rates.
Zachary Schiffman, Feihu Yan, Shihua He, Kevin Tierney, Wenjun Zhu, Karla Emeterio, Huajun Zhang, Logan Banadyga, Xiangguo Qiu   +8 more
doaj   +1 more source

Seroprevalence of Ebola virus infection in Bombali District, Sierra Leone [PDF]

, 2017
A serosurvey of anti-Ebola Zaire virus nucleoprotein IgG prevalence was carried out among Ebola virus disease survivors and their Community Contacts in Bombali District, Sierra Leone. Our data suggest that the specie of Ebola virus (Zaire) responsible of
Antonella Minutolo, Brima Kargbo, Carla Montesano, Ebola Study Group, Emmanuel Iwerima, Gianluca Russo, Marta Giovanetti, Massimo Amicosante, Mattei Maurizio, Nadege Goumkwa Mafopa, Patrick Turay, Raoul Emeric Guetiya Wadoum, Thomas B. Turay, Vincent Batwala   +13 more
core   +2 more sources

Standardization of the Filovirus Plaque Assay for Use in Preclinical Studies

Viruses, 2012
The filovirus plaque assay serves as the assay of choice to measure infectious virus in a cell culture, blood, or homogenized tissue sample. It has been in use for more than 30 years and is the generally accepted assay used to titrate virus in samples ...
Gene G. Olinger, Ana Kuehne, Jennifer L. Audet, Kendra J. Alfson, Anthony Griffiths, Holly A. Bloomfield, Elizabeth E. Zumbrun, Ashley E. Keeney, Julia E. Biggins, Amy C. Shurtleff, Sina Bavari   +10 more
doaj   +1 more source

Comprehensive Enteroviral Serology Links Infection and Anti‐Melanoma Differentiation‐Associated Protein 5 Dermatomyositis

ACR Open Rheumatology, Volume 7, Issue 1, January 2025.
Objective Idiopathic inflammatory myopathies (IIMs) are a group of heterogeneous, systemic autoimmune diseases characterized by specific clinical features and, frequently, skeletal muscle inflammation. Specific subtypes of IIMs can be characterized by myositis‐specific autoantibodies and are associated with distinct clinical phenotypes.
Sahana Jayaraman, Eleni Tiniakou, William R. Morgenlander, Miso Na, Lisa Christopher‐Stine, H. Benjamin Larman   +5 more
wiley   +1 more source

Characterization of Sudan Ebolavirus infection in ferrets

Oncotarget, 2017
Sudan virus (SUDV) outbreaks in Africa are highly lethal; however, the development and testing of novel antivirals and vaccines for this virus has been limited by a lack of suitable animal models. Non-human primates (NHP) remain the gold standard for modeling filovirus disease, but they are not conducive to screening large numbers of experimental ...
Andrea Kroeker, Andrea Kroeker, Shihua He, Shihua He, Marc-Antoine de La Vega, Marc-Antoine de La Vega, Marc-Antoine de La Vega, Gary Wong, Gary Wong, Xiangguo Qiu, Xiangguo Qiu, Carissa Embury-Hyatt   +11 more
openaire   +3 more sources

Replication-Deficient Ebolavirus as a Vaccine Candidate [PDF]

Journal of Virology, 2009
ABSTRACT Ebolavirus causes severe hemorrhagic fever, with case fatality rates as high as 90%. Currently, no licensed vaccine is available against Ebolavirus. We previously generated a replication-deficient, biologically contained Ebolavirus, EbolaΔVP30, which lacks the essential VP30 gene, grows only in cells stably expressing ...
Shinji Watanabe, Yasuko Hatta, Gabriele Neumann, Hideki Ebihara, Hideki Ebihara, Heinz Feldmann, Heinz Feldmann, Peter Halfmann, Andrea Marzi, M. Suresh, Yoshihiro Kawaoka, Yoshihiro Kawaoka   +11 more
openaire   +3 more sources

Generalidades de la familia Filoviridae y el virus del Ébola: una actualización de sus implicaciones en la población humana

, 2020
Characteristics of the family Filoviridae and the Ebola virus: an update of its implications in the human population The family Filoviridae is integrated by a group of filamentous RNA viruses that cause severe hemorrhagic fevers in primates and other ...
Burgueño-Sosa, E., Esquivel Gómez, L., León-López, A., Rivadeneyra-Gutiérrez, E.   +3 more
core   +1 more source

Influence of Host and Landscape‐Associated Factors in the Infection and Transmission of Pathogens: The Case of Directly Transmitted Virus in Mammals

Veterinary Medicine and Science, Volume 11, Issue 1, January 2025.
The figure shows the effects (increasing upward arrow or decreasing downward arrow) the most common host traits, landscape attributes, climatic features and anthropogenic variables recorded in the review had on the infection and transmission of directly transmitted virus to mammals.
María del Carmen Villalobos‐Segura, Oscar Rico‐Chávez, Gerardo Suzán, Andrea Chaves   +3 more
wiley   +1 more source

Predictive and comparative analysis of Ebolavirus proteins [PDF]

Cell Cycle, 2015
Ebolavirus is the pathogen for Ebola Hemorrhagic Fever (EHF). This disease exhibits a high fatality rate and has recently reached a historically epidemic proportion in West Africa. Out of the 5 known Ebolavirus species, only Reston ebolavirus has lost human pathogenicity, while retaining the ability to cause EHF in long-tailed macaque.
Nick V. Grishin, Qian Cong, Jimin Pei
openaire   +3 more sources