Results 11 to 20 of about 13,687 (277)
Pathogens, 2022 Intravenous (IV) administration of antiviral monoclonal antibodies (mAbs) can be challenging, particularly during an ongoing epidemic, due to the considerable resources required for performing infusions.
Erin Kuang +17 more
doaj +4 more sources
Ebolavirus evolution and emergence are associated with land use change. [PDF]
Ecol MonogrAnthropogenic land use change facilitates disease emergence by altering the interface between humans and pathogen reservoirs and is hypothesized to drive pathogen evolution.
Lange CE +8 more
europepmc +3 more sources
Ebolavirus replication and Tetherin/BST-2 [PDF]
Frontiers in Microbiology, 2012 Ebolavirus (EBOV) is an enveloped, non-segmented, negative-stranded RNA virus, which consists of five species: Zaire ebolavirus (ZEBOV), Sudan ebolavirus (SEBOV), Tai Forest ebolavirus (TFEBOV), Bundibugyo ebolavirus (BEBOV), and Reston ebolavirus (REBOV)
Jiro eYasuda
doaj +3 more sources
Traits, phylogeny and host cell receptors predict Ebolavirus host status among African mammals.
PLoS Neglected Tropical Diseases, 2022 We explore how animal host traits, phylogenetic identity and cell receptor sequences relate to infection status and mortality from ebolaviruses. We gathered exhaustive databases of mortality from Ebolavirus after exposure and infection status based on ...
Mekala Sundaram +4 more
doaj +2 more sources
Revista Gestão & Saúde, 2015 O atual surto de ebola tem devastado centenas de vidas, preocupando a comunidade cientifica devido à alta letalidade e difícil controle. Objetivamos observar quais os principais desafios para o controle do vírus e entender a importância de uma gestão ...
Rachid Figueirôa Souza +4 more
doaj +1 more source
Bombali Ebolavirus in Mops condylurus Bats (Molossidae), Mozambique
Emerging Infectious Diseases, 2022 We detected Bombali ebolavirus RNA in 3 free-tailed bats (Mops condylurus, Molossidae) in Mozambique. Sequencing of the large protein gene revealed 98% identity with viruses previously detected in Sierra Leone, Kenya, and Guinea.
Camille Lebarbenchon +9 more
doaj +2 more sources
Design and characterization of protective pan-ebolavirus and pan-filovirus bispecific antibodies.
PLoS PathogensMonoclonal antibodies (mAbs) are an important class of antiviral therapeutics. MAbs are highly selective, well tolerated, and have long in vivo half-life as well as the capacity to induce immune-mediated virus clearance.
Ariel S Wirchnianski +21 more
doaj +2 more sources
Lactic acid bacterial surface display of scytovirin inhibitors for anti-ebolavirus infection [PDF]
Frontiers in Microbiology, 2023 Scytovirin (SVN) is a lectin from cyanobacteria which has a strong inhibitory activity against Ebola virus infection. We engineered scytovirin as the inhibitor for surface display of lactic acid bacteria to block Ebola virus infection.
Joshua Wiggins +5 more
openalex +2 more sources
Glycan shield of the ebolavirus envelope glycoprotein GP [PDF]
Communications Biology, 2022 The envelope glycoprotein GP of the ebolaviruses is essential for host cell entry and the primary target of the host antibody response. GP is heavily glycosylated with up to 17 N-linked sites, numerous O-linked glycans in its disordered mucin-like domain
Weiwei Peng +9 more
openalex +2 more sources
Predictive Model for Estimating Annual Ebolavirus Spillover Potential. [PDF]
Emerg Infect DisForest changes, human population dynamics, and meteorologic conditions have been associated with zoonotic Ebolavirus spillover into humans. High-resolution spatial data for those variables can be used to produce estimates of spillover potential and ...
Telford CT +5 more
europepmc +2 more sources