Results 11 to 20 of about 12,943 (270)
Pathogens, 2022 Intravenous (IV) administration of antiviral monoclonal antibodies (mAbs) can be challenging, particularly during an ongoing epidemic, due to the considerable resources required for performing infusions.
Erin Kuang +17 more
doaj +4 more sources
Fruit-frugivore dependencies are important in Ebolavirus outbreaks in Sub-Saharan Africa. [PDF]
EcographyEbolaviruses have the ability to infect a wide variety of species, with many African mammals potentially serving either as primary reservoirs or secondary amplifying hosts.
Sundaram M +8 more
europepmc +3 more sources
Glycan shield of the ebolavirus envelope glycoprotein GP [PDF]
Communications Biology, 2022 The envelope glycoprotein GP of the ebolaviruses is essential for host cell entry and the primary target of the host antibody response. GP is heavily glycosylated with up to 17 N-linked sites, numerous O-linked glycans in its disordered mucin-like domain
W. Peng +9 more
semanticscholar +8 more sources
Ebolavirus evolution and emergence are associated with land use change
Ecological Monographs, Volume 95, Issue 1, February 2025.Anthropogenic land use change facilitates disease emergence by altering the interface between humans and pathogen reservoirs and is hypothesized to drive pathogen evolution.
Christian E. Lange +8 more
semanticscholar +3 more sources
PLoS Neglected Tropical Diseases, 2022 Although multiple antigenically distinct ebolavirus species can cause human disease, previous serosurveys focused on only Zaire ebolavirus (EBOV). Thus, the extent of reactivity or exposure to other ebolaviruses, and which sociodemographic factors are ...
Kelly C L Shaffer +18 more
doaj +2 more sources
Traits, phylogeny and host cell receptors predict Ebolavirus host status among African mammals.
PLoS Neglected Tropical Diseases, 2022 We explore how animal host traits, phylogenetic identity and cell receptor sequences relate to infection status and mortality from ebolaviruses. We gathered exhaustive databases of mortality from Ebolavirus after exposure and infection status based on ...
Mekala Sundaram +4 more
doaj +2 more sources
Rapid detection of Ebolavirus using isothermal recombinase‐aided amplification
Journal of Medical Virology, Volume 96, Issue 6, June 2024.Ebolavirus disease (EVD) is an often‐lethal disease caused by the genus Ebolavirus (EBOV). Although vaccines are being developed and recently used, outbreak control still relies on a combination of various factors, including rapid identification of EVD ...
Arianna Ceruti +8 more
semanticscholar +2 more sources
Bombali Ebolavirus in Mops condylurus Bats (Molossidae), Mozambique
Emerging Infectious Diseases, 2022 We detected Bombali ebolavirus RNA in 3 free-tailed bats (Mops condylurus, Molossidae) in Mozambique. Sequencing of the large protein gene revealed 98% identity with viruses previously detected in Sierra Leone, Kenya, and Guinea.
Camille Lebarbenchon +9 more
doaj +2 more sources
Serological evidence of ebolavirus infection in bats, China [PDF]
Virology Journal, 2012 Background The genus Ebolavirus of the family Filoviridae currently consists of five species. All species, with the exception of Reston ebolavirus, have been found in Africa and caused severe human diseases.
Yuan Junfa +5 more
doaj +4 more sources
Design and characterization of protective pan-ebolavirus and pan-filovirus bispecific antibodies.
PLoS PathogensMonoclonal antibodies (mAbs) are an important class of antiviral therapeutics. MAbs are highly selective, well tolerated, and have long in vivo half-life as well as the capacity to induce immune-mediated virus clearance.
Ariel S Wirchnianski +21 more
doaj +2 more sources