Results 11 to 20 of about 12,455 (266)
Pathogens, 2022 Intravenous (IV) administration of antiviral monoclonal antibodies (mAbs) can be challenging, particularly during an ongoing epidemic, due to the considerable resources required for performing infusions.
Erin Kuang +17 more
doaj +4 more sources
Glycan shield of the ebolavirus envelope glycoprotein GP [PDF]
Communications Biology, 2022 The envelope glycoprotein GP of the ebolaviruses is essential for host cell entry and the primary target of the host antibody response. GP is heavily glycosylated with up to 17 N-linked sites, numerous O-linked glycans in its disordered mucin-like domain
W. Peng +9 more
semanticscholar +8 more sources
Frontiers in Immunology, 2022 Monoclonal antibodies (mAbs) have proven effective for the treatment of ebolavirus infection in humans, with two mAb-based drugs Inmazeb™ and Ebanga™ receiving FDA approval in 2020.
Charles D. Murin +5 more
doaj +2 more sources
PLoS Neglected Tropical Diseases, 2022 Although multiple antigenically distinct ebolavirus species can cause human disease, previous serosurveys focused on only Zaire ebolavirus (EBOV). Thus, the extent of reactivity or exposure to other ebolaviruses, and which sociodemographic factors are ...
Kelly C L Shaffer +18 more
doaj +2 more sources
Bombali Ebolavirus in Mops condylurus Bats (Molossidae), Mozambique
Emerging Infectious Diseases, 2022 We detected Bombali ebolavirus RNA in 3 free-tailed bats (Mops condylurus, Molossidae) in Mozambique. Sequencing of the large protein gene revealed 98% identity with viruses previously detected in Sierra Leone, Kenya, and Guinea.
Camille Lebarbenchon +9 more
doaj +2 more sources
Traits, phylogeny and host cell receptors predict Ebolavirus host status among African mammals.
PLoS Neglected Tropical Diseases, 2022 We explore how animal host traits, phylogenetic identity and cell receptor sequences relate to infection status and mortality from ebolaviruses. We gathered exhaustive databases of mortality from Ebolavirus after exposure and infection status based on ...
Mekala Sundaram +4 more
doaj +2 more sources
Tracking ebolavirus genomic drift with a resequencing microarray.
PLoS ONE, 2022 Filoviruses are emerging pathogens that cause acute fever with high fatality rate and present a global public health threat. During the 2013-2016 Ebola virus outbreak, genome sequencing allowed the study of virus evolution, mutations affecting ...
Irina Tiper +7 more
doaj +2 more sources
Ebolavirus and Marburgvirus: insight the Filoviridae family [PDF]
Molecular Aspects of Medicine, 2008 Ebolavirus and Marburgvirus (belonging to the Filoviridae family) emerged four decades ago and cause epidemics of haemorrhagic fever with high case-fatality rates. The genome of filoviruses encodes seven proteins.
A. Bocedi +7 more
core +10 more sources
Rapid detection of Ebolavirus using isothermal recombinase‐aided amplification
Journal of Medical Virology, Volume 96, Issue 6, June 2024.Abstract Ebolavirus disease (EVD) is an often‐lethal disease caused by the genus Ebolavirus (EBOV). Although vaccines are being developed and recently used, outbreak control still relies on a combination of various factors, including rapid identification of EVD cases. This allows rapid patient isolation and control measure implementation.
Arianna Ceruti +8 more
wiley +2 more sources
Influence of Host and Landscape-Associated Factors in the Infection and Transmission of Pathogens: The Case of Directly Transmitted Virus in Mammals. [PDF]
Vet Med SciThe figure shows the effects (increasing upward arrow or decreasing downward arrow) the most common host traits, landscape attributes, climatic features and anthropogenic variables recorded in the review had on the infection and transmission of directly transmitted virus to mammals.
Villalobos-Segura MDC +3 more
europepmc +2 more sources