Cryo-EM structure of Sudan ebolavirus glycoprotein complexed with its human endosomal receptor NPC1 [PDF]
Communications BiologySudan ebolavirus (SUDV), like Ebola ebolavirus (EBOV), poses a significant threat to global health and security due to its high lethality. However, unlike EBOV, there are no approved vaccines or treatments for SUDV, and its structural interaction with ...
Fan Bu +5 more
doaj +3 more sources
rVSV-ZEBOV vaccination in people with pre-existing immunity to Ebolavirus: an open-label safety and immunogenicity study in Guinean communities affected by Ebola virus disease (l’essai proches) [PDF]
BMC MedBackground Zaire Ebolavirus disease (EVD) outbreaks can be controlled using rVSV-ZEBOV vaccination and other public health measures. People in high-risk areas may have pre-existing antibodies from asymptomatic Ebolavirus exposure that might affect ...
Conall H. Watson +36 more
semanticscholar +3 more sources
Resurgence of Ebola in Uganda: Response Strategies, Lessons Learned, and Future Directions [PDF]
Health Science Reports, Volume 8, Issue 7, July 2025.ABSTRACT Introduction The recent resurgence of Ebola virus disease (EVD), specifically the Sudan virus strain, in Uganda highlights the ongoing threat of emerging infectious diseases. This article aims to analyze the multifaceted factors contributing to this resurgence, evaluate the public health impact, and assess the effectiveness of response ...
Majani Edward +3 more
wiley +2 more sources
Filovirus RefSeq Entries: Evaluation and Selection of Filovirus Type Variants, Type Sequences, and Names [PDF]
Viruses, 2014 Sequence determination of complete or coding-complete genomes of viruses is becoming common practice for supporting the work of epidemiologists, ecologists, virologists, and taxonomists.
Jens H. Kuhn +75 more
doaj +5 more sources
The Molecular Genetic Peculiarities of Genomic Structure of Members of the Ebolavirus Genus
Проблемы особо опасных инфекций, 2015 The molecular genetic peculiarities of genomic structure of the Ebolavirus genus members are viewed in the review. The Ebola virus disease outbreaks in West African countries constitute a threat not only for Africa, but for the whole world in view of ...
A. A. Petrov +8 more
doaj +3 more sources
Glycan shield of the ebolavirus envelope glycoprotein GP [PDF]
Communications Biology, 2022 The envelope glycoprotein GP of the ebolaviruses is essential for host cell entry and the primary target of the host antibody response. GP is heavily glycosylated with up to 17 N-linked sites, numerous O-linked glycans in its disordered mucin-like domain
W. Peng +9 more
semanticscholar +8 more sources
Rapid detection of Ebolavirus using isothermal recombinase‐aided amplification
Journal of Medical Virology, Volume 96, Issue 6, June 2024.Ebolavirus disease (EVD) is an often‐lethal disease caused by the genus Ebolavirus (EBOV). Although vaccines are being developed and recently used, outbreak control still relies on a combination of various factors, including rapid identification of EVD ...
Arianna Ceruti +8 more
semanticscholar +2 more sources
Natural History of Sudan ebolavirus to Support Medical Countermeasure Development [PDF]
Vaccines, 2022 Sudan ebolavirus (SUDV) is one of four members of the Ebolavirus genus known to cause Ebola Virus Disease (EVD) in humans, which is characterized by hemorrhagic fever and a high case fatality rate.
Caroline Carbonnelle +18 more
openalex +2 more sources
Risks Posed by Reston, the Forgotten Ebolavirus [PDF]
mSphere, 2016 Out of the five members of the Ebolavirus family, four cause lifethreatening disease, whereas the fifth, Reston virus (RESTV), is nonpathogenic in humans. The reasons for this discrepancy remain unclear. In this review, we analyze the currently available
Arran Hamlet +5 more
core +8 more sources
Informatics in Medicine Unlocked, 2021 Bombali Ebolavirus belongs to the RNA group of viruses which causes lethal hemorrhagic fever with a high mortality rate. Despite these facts, yet there is no approved vaccine have been developed for the eradication of Bombali Ebolavirus infections ...
Mujahed I. Mustafa +3 more
doaj +2 more sources