Results 31 to 40 of about 12,455 (266)
Natural History of Sudan ebolavirus to Support Medical Countermeasure Development [PDF]
Vaccines, 2022 Sudan ebolavirus (SUDV) is one of four members of the Ebolavirus genus known to cause Ebola Virus Disease (EVD) in humans, which is characterized by hemorrhagic fever and a high case fatality rate.
Caroline Carbonnelle +18 more
openalex +2 more sources
, 2021 The genus Ebolavirus from the family Filoviridae is composed of five species including Sudan Ebolavirus, Reston Ebolavirus, Bundibugyo Ebolavirus, Taï Forest Ebolavirus, and Zaire Ebolavirus The transmission of these viruses to human body is via direct ...
Pada, Meis Rafelin
core +2 more sources
Mapping of Ebola virus spillover: Suitability and seasonal variability at the landscape scale [PDF]
PLOS Neglected Tropical Diseases 15, e0009683 (2021), 2021 The unexpected Ebola virus outbreak in West Africa in 2014 involving the Zaire ebolavirus made clear that other regions outside Central Africa, its previously documented niche, were at risk of future epidemics. The complex transmission cycle and a lack of epidemiological data make mapping areas at risk of the disease challenging.
arxiv +1 more source
Frontiers in Pharmacology, 2023 On 20 September 2022, the Ministry of Health in Uganda, together with the World Health Organization—Regional Office for Africa (WHO AFRO) confirmed an outbreak of EVD due to Sudan ebolavirus in Mubende District, after one fatal case was confirmed.
Francesco Branda +4 more
semanticscholar +1 more source
Cell, 2017 Ebola virus disease poses a global health threat. Here, two studies by Wec et al. and Zhao et al. identified vulnerability in an internal fusion loop of an ebolavirus glycoprotein. Monoclonal antibodies elicited from immunization and isolated from a human survivor that recognized epitopes in this area neutralized all five ebolaviruses, guiding the ...
Seiya Yamayoshi +2 more
openaire +3 more sources
A Pan-ebolavirus Monoclonal Antibody Cocktail Provides Protection against Ebola and Sudan Viruses.
Journal of Infectious Diseases, 2023 Filoviruses, including ebolaviruses and marburgviruses, can cause severe and often fatal disease in humans. Over the past several years, antibody therapy has emerged as a promising strategy for the treatment of filovirus disease.
Guodong Liu +12 more
semanticscholar +1 more source
Ebolaviruses: New roles for old proteins. [PDF]
PLoS Neglected Tropical Diseases, 2018 In 2014, the world witnessed the largest Ebolavirus outbreak in recorded history. The subsequent humanitarian effort spurred extensive research, significantly enhancing our understanding of ebolavirus replication and pathogenicity.
Diego Cantoni, Jeremy S Rossman
doaj +1 more source
Ebolavirus Species-Specific Interferon Antagonism Mediated by VP24
Viruses, 2023 Members of the Ebolavirus genus demonstrate a marked differences in pathogenicity in humans with Ebola (EBOV) being the most pathogenic, Bundibugyo (BDBV) less pathogenic, and Reston (RESTV) is not known to cause a disease in humans.
Palaniappan Ramanathan +11 more
semanticscholar +1 more source
Ebolavirus Δ-Peptide Immunoadhesins Inhibit Marburgvirus and Ebolavirus Cell Entry [PDF]
Journal of Virology, 2011 ABSTRACT With the exception of Reston and Lloviu viruses, filoviruses (marburgviruses, ebolaviruses, and “cuevaviruses”) cause severe viral hemorrhagic fevers in humans. Filoviruses use a class I fusion protein, GP 1,2 , to bind to an unknown, but shared, cell surface receptor to initiate virus-cell fusion.
Krishna P. Kota +21 more
openaire +3 more sources
Expert Review of Vaccines, 2023 BACKGROUND This review aimed to systematically evaluate the immunogenicity and safety of the candidate ebolavirus vaccine (EVV). METHODS We searched five databases for randomized controlled trials (RCTs) evaluating the effects of EVV on healthy adults.
Mingsan Miao +4 more
semanticscholar +1 more source