Results 31 to 40 of about 12,924 (266)
Depletion of Bone Marrow Hematopoietic Cells in Ebolavirus-Infected Rhesus Macaques [PDF]
American Journal of Pathology, 2023 David X. Liu +16 more
openalex +2 more sources
Characterization of Ebolavirus regulatory genomic regions [PDF]
Virus Research, 2009 For filoviruses, such as Ebolavirus and the closely related Marburgvirus, transcriptional regulation is poorly understood. The open reading frames (ORFs) that encode the viral proteins are separated by regulatory regions composed of the 3' nontranslated region (NTR) of the upstream gene, highly conserved transcription stop and start signals, and the 5 ...
Gabriele Neumann +2 more
openalex +3 more sources
Ebolavirus is internalized into host cells via macropinocytosis in a viral glycoprotein-dependent manner. [PDF]
PLoS Pathogens, 2010 Ebolavirus (EBOV) is an enveloped, single-stranded, negative-sense RNA virus that causes severe hemorrhagic fever with mortality rates of up to 90% in humans and nonhuman primates.
Asuka Nanbo +7 more
doaj +1 more source
Ebolaviruscomparative genomics [PDF]
FEMS Microbiology Reviews, 2015 (Uploaded by Plazi for the Bat Literature Project) The 2014 Ebola outbreak in West Africa is the largest documented for this virus. To examine the dynamics of this genome, we compare more than 100 currently available ebolavirus genomes to each other and to other viral genomes.
Qian Zhang +19 more
openaire +5 more sources
Cell, 2017 Ebola virus disease poses a global health threat. Here, two studies by Wec et al. and Zhao et al. identified vulnerability in an internal fusion loop of an ebolavirus glycoprotein. Monoclonal antibodies elicited from immunization and isolated from a human survivor that recognized epitopes in this area neutralized all five ebolaviruses, guiding the ...
Seiya Yamayoshi +2 more
openaire +3 more sources
Ebolaviruses: New roles for old proteins. [PDF]
PLoS Neglected Tropical Diseases, 2018 In 2014, the world witnessed the largest Ebolavirus outbreak in recorded history. The subsequent humanitarian effort spurred extensive research, significantly enhancing our understanding of ebolavirus replication and pathogenicity.
Diego Cantoni, Jeremy S Rossman
doaj +1 more source
Frontiers in Pharmacology, 2023 On 20 September 2022, the Ministry of Health in Uganda, together with the World Health Organization—Regional Office for Africa (WHO AFRO) confirmed an outbreak of EVD due to Sudan ebolavirus in Mubende District, after one fatal case was confirmed.
Francesco Branda +4 more
semanticscholar +1 more source
Revista Ciencias Biomédicas, 2020 La entidad conocida como ébola, recibe esa denominación por el nombre del río más cercano al distrito africano, donde se presentaron los primeros casos del brote en la década de los setenta del siglo XX (1).
Comité Editorial
doaj +1 more source
A Pan-ebolavirus Monoclonal Antibody Cocktail Provides Protection against Ebola and Sudan Viruses.
Journal of Infectious Diseases, 2023 Filoviruses, including ebolaviruses and marburgviruses, can cause severe and often fatal disease in humans. Over the past several years, antibody therapy has emerged as a promising strategy for the treatment of filovirus disease.
Guodong Liu +12 more
semanticscholar +1 more source
Ebolavirus Δ-Peptide Immunoadhesins Inhibit Marburgvirus and Ebolavirus Cell Entry [PDF]
Journal of Virology, 2011 ABSTRACT With the exception of Reston and Lloviu viruses, filoviruses (marburgviruses, ebolaviruses, and “cuevaviruses”) cause severe viral hemorrhagic fevers in humans. Filoviruses use a class I fusion protein, GP 1,2 , to bind to an unknown, but shared, cell surface receptor to initiate virus-cell fusion.
Krishna P. Kota +21 more
openaire +3 more sources