Results 41 to 50 of about 12,943 (270)
Tracking ebolavirus genomic drift with a resequencing microarray.
PLoS ONE, 2022 Filoviruses are emerging pathogens that cause acute fever with high fatality rate and present a global public health threat. During the 2013-2016 Ebola virus outbreak, genome sequencing allowed the study of virus evolution, mutations affecting ...
Irina Tiper +7 more
doaj +1 more source
Epidemiology of Ebolaviruses from an Etiological Perspective
Pathogens, 2023 Since the inception of the ebolavirus in 1976, 32 outbreaks have resulted in nearly 15,350 deaths in more than ten countries of the African continent. In the last decade, the largest (2013–2016) and second largest (2018–2020) ebolavirus outbreaks have ...
Sahil Jain +4 more
doaj +1 more source
RNA binding motif 4 inhibits the replication of ebolavirus by directly targeting 3′-leader region of genomic RNA [PDF]
Emerging Microbes and InfectionsEbola virus (EBOV) belongs to Filoviridae family possessing single-stranded negative-sense RNA genome, which is a serious threat to human health. Nowadays, no therapeutics have been proven to be successful in efficiently decreasing the mortality rate ...
Linjin Fan +14 more
openalex +2 more sources
Re-emergence of Sudan ebolavirus after a decade: new challenge to Ebola control
International Journal of Surgery, 2023 Dear Editor, Outbreaks of African filoviruses often have resulted into high mortality, and of these, the West Africa Ebola outbreak during 2014–2016 accounted for more than 11 000 deaths among around 28 000 cases.
R. Sah +8 more
semanticscholar +1 more source
Ebolavirus and Other Filoviruses [PDF]
, 2007 (Uploaded by Plazi for the Bat Literature Project) Since Ebola fever emerged in Central Africa in 1976, a number of studies have been undertaken to investigate its natural history and to characterize its transmission from a hypothetical reservoir host(s) to humans.
Xavier Pourrut +2 more
openaire +3 more sources
Autophagy, 2022 Zaire ebolavirus (EBOV) causes a severe hemorrhagic fever in humans and non-human primates with high morbidity and mortality. EBOV infection is dependent on its structural glycoprotein (GP), but high levels of GP expression also trigger cell rounding ...
Bin Wang +10 more
semanticscholar +1 more source
Ebolavirus: Pseudotypes, Libraries and Standards [PDF]
Future Virology, 2015 Globalization, accompanied by increasing levels of international travel and trade, climate change, altered human behavior and demographics, is leading to the emergence of manifold viral diseases, many of which are highly pathogenic and hence are considered of great public and animal health importance to the global populace [1].
Nigel J. Temperton, Mark Page
openaire +3 more sources
Natural history of Sudan ebolavirus infection in rhesus and cynomolgus macaques
Emerging Microbes and Infections, 2022 Due to its high mortality rate and continued re-emergence, Ebolavirus disease (EVD) continues to pose a serious threat to global health. A group of viruses within the genus Ebolavirus causes this severe hemorrhagic disease in humans: Ebola virus (EBOV ...
Courtney Woolsey +10 more
semanticscholar +1 more source
Ebolavirus vaccines for humans and apes [PDF]
Current Opinion in Virology, 2012 Because of high case fatality proportions, person-to-person transmission, and potential use in bioterrorism, the development of a vaccine against ebolavirus remains a top priority. Although no licensed vaccine or treatment against ebolavirus is currently available, progress in preclinical testing of countermeasures has been made.
Hugues Fausther-Bovendo +2 more
openaire +3 more sources
Ebolavirus Evolution: Past and Present
PLOS Pathogens, 2015 The past year has marked the most devastating Ebola outbreak the world has ever witnessed, with over 28,000 cases and over 11,000 deaths. Ebola virus (EBOV) has now been around for almost 50 years. In this review, we discuss past and present outbreaks of EBOV and how those variants evolved over time.
Derek R. Stein +4 more
openaire +7 more sources