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La entidad conocida como ébola, recibe esa denominación por el nombre del río más cercano al distrito africano, donde se presentaron los primeros casos del brote en la década de los setenta del siglo XX (1).
Comité Editorial
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Pathogenicity and Virulence of Ebolaviruses with Species- and Variant-specificity
Ebola virus (EBOV), belonging to the species Zaire ebolavirus in the genus Ebolavirus, causes a severe febrile illness in humans with case fatality rates (CFRs) up to 90%.
Satoko Yamaoka, Hideki Ebihara
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Re-emergence of Sudan ebolavirus after a decade: new challenge to Ebola control
Dear Editor, Outbreaks of African filoviruses often have resulted into high mortality, and of these, the West Africa Ebola outbreak during 2014–2016 accounted for more than 11 000 deaths among around 28 000 cases.
R. Sah+8 more
semanticscholar +1 more source
Past research has found associations between ebolavirus spillover and forest loss and fragmentation, although most predictions of the spatial distribution of ebolaviruses have not utilized these data.
C. T. T. Mph+6 more
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One-Step Reverse-Transcription FRET-PCR for Differential Detection of Five Ebolavirus Species. [PDF]
Ebola is an emerging infectious disease caused by a deadly virus belonging to the family Filoviridae, genus Ebolavirus. Based on their geographical distribution, Ebolavirus has been classified into total five species so far, mainly Zaire, Sudan, Taï ...
Guangwu Lu+6 more
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Lactic acid bacterial surface display of scytovirin inhibitors for anti-ebolavirus infection
Scytovirin (SVN) is a lectin from cyanobacteria which has a strong inhibitory activity against Ebola virus infection. We engineered scytovirin as the inhibitor for surface display of lactic acid bacteria to block Ebola virus infection.
J. Wiggins+5 more
semanticscholar +1 more source
Early detection of Ebola virus spillover into wildlife is crucial for rapid response. We developed and validated a portable, cold-chain independent Ebola virus RT-qPCR assay.
Dania M. Figueroa+14 more
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RNA binding motif 4 inhibits the replication of ebolavirus by directly targeting 3′-leader region of genomic RNA [PDF]
Ebola virus (EBOV) belongs to Filoviridae family possessing single-stranded negative-sense RNA genome, which is a serious threat to human health. Nowadays, no therapeutics have been proven to be successful in efficiently decreasing the mortality rate ...
Linjin Fan+14 more
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Natural history of Sudan ebolavirus infection in rhesus and cynomolgus macaques
Due to its high mortality rate and continued re-emergence, Ebolavirus disease (EVD) continues to pose a serious threat to global health. A group of viruses within the genus Ebolavirus causes this severe hemorrhagic disease in humans: Ebola virus (EBOV ...
Courtney Woolsey+10 more
semanticscholar +1 more source
Ebolavirus vaccines for humans and apes [PDF]
Because of high case fatality proportions, person-to-person transmission, and potential use in bioterrorism, the development of a vaccine against ebolavirus remains a top priority. Although no licensed vaccine or treatment against ebolavirus is currently available, progress in preclinical testing of countermeasures has been made.
Hugues Fausther-Bovendo+2 more
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