Need of surveillance response systems to combat Ebola outbreaks and other emerging infectious diseases in African countries [PDF]
, 2014 There is growing concern in Sub-Saharan Africa about the spread of the Ebola virus disease (EVD), formerly known as Ebola haemorrhagic fever, and the public health burden that it ensues.
Emmanuel Ugwu +2 more
core +6 more sources
Plant phenology supports the multi-emergence hypothesis for ebola spillover events [PDF]
, 2017 Ebola virus disease outbreaks in animals (including humans and great apes) start with sporadic host switches from unknown reservoir species. The factors leading to such spillover events are little explored.
Douglas, Noah E. +6 more
core +1 more source
Tenacious Researchers Identify a Weakness in All Ebolaviruses. [PDF]
, 2018 The Ebolavirus genus has at least five members, four of which are known to cause deadly disease in humans. An ideal therapy or a vaccine would protect against all ebolaviruses, but identifying a common weakness in all of them has remained elusive.
DuBois, Rebecca M
core +1 more source
A seroepidemiologic study of Reston ebolavirus in swine in the Philippines [PDF]
BMC Veterinary Research, 2012 Abstract Background Ebola viruses cause viral hemorrhagic fever in humans and non-human primates and are endemic in Africa. Reston ebolavirus (REBOV) has caused several epizootics in cynomolgus monkeys (Macaca fascicularis) but is not associated with any human disease. In late 2008, REBOV infections were identified in
Rachel R. Azul +21 more
core +6 more sources
Protease inhibitors targeting coronavirus and filovirus entry. [PDF]
, 2015 In order to gain entry into cells, diverse viruses, including Ebola virus, SARS-coronavirus and the emerging MERS-coronavirus, depend on activation of their envelope glycoproteins by host cell proteases.
Agudelo, Juliet +10 more
core +1 more source
Virological diagnosis of Ebolavirus infection
Pathology, 2015 Ebolaviruses, and the other viral causes of haemorrhagic fevers (VHF) have always posed special problems for diagnostic laboratories. These arise from the rarity of human infections, minimal documented experience with test delivery and interpretation, the paucity of established commercial or in-house assays, the lack of clinical material for test ...
Dominic E. Dwyer +6 more
openaire +3 more sources
Re-emerging infectious diseases: Ebola hemorrhagic fever [PDF]
Romanian Journal of Military Medicine, 2014 The spring of 2014 has brought a new calamity, the exotic infectious disease: Ebola Hemorrhagic Fever, which is caused by a highly contagious and pathogenic virus, transmitted directly by interpersonal contact or indirectly by common usage of objects ...
Lucia E. Ionescu +2 more
doaj
Potent neutralizing monoclonal antibodies against Ebola virus isolated from vaccinated donors
mAbs, 2020 Ebola virus (EBOV) can cause severe hemorrhagic fever in humans, and no approved treatment is currently available. Although several antibodies have achieved good protection in animal models, the potential emerging isolates of ebolavirus and the unknown ...
Pengfei Fan +12 more
doaj +1 more source
Putative endogenous filovirus VP35-like protein potentially functions as an IFN antagonist but not a polymerase cofactor. [PDF]
PLoS ONE, 2017 It has been proposed that some non-retroviral RNA virus genes are integrated into vertebrate genomes. Endogenous filovirus-like elements (EFLs) have been discovered in some mammalian genomes.
Tatsunari Kondoh +13 more
doaj +1 more source
The face of Ebola: changing frequency of haemorrhage in the West African compared with Eastern-Central African outbreaks [PDF]
, 2015 BACKGROUND: The West-African (WA) Zaire Ebolavirus disease (EVD) outbreak was characterized by an exceptionally high number of cases and deaths as compared with the Eastern-Central African (ECA) outbreaks.
Crispian Scully +4 more
core +4 more sources