Results 1 to 10 of about 17,129 (220)

Azadirachtin disrupts ecdysone signaling and alters sand fly immunity [PDF]

Parasites & Vectors
Background Leishmaniasis is a group of neglected vector-borne diseases transmitted by phlebotomine sand flies. Leishmania parasites must overcome various defenses in the sand fly midgut, including the insects’s immune response.
Cecilia Stahl Vieira, Sara Bisogno, Marco Salvemini, Erich Loza Telleria, Petr Volf   +4 more
doaj   +2 more sources

Ecdysone coordinates plastic growth with robust pattern in the developing wing

eLife, 2022
Animals develop in unpredictable, variable environments. In response to environmental change, some aspects of development adjust to generate plastic phenotypes.
André Nogueira Alves, Marisa Mateus Oliveira, Takashi Koyama, Alexander Shingleton, Christen Kerry Mirth   +4 more
doaj   +1 more source

Larval diapause termination in the bamboo borer, Omphisa fuscidentalis. [PDF]

PLoS ONE, 2017
In insects, juvenile hormone (JH) and 20-hydroxyecdysone (20E) regulate larval growth and molting. However, little is known about how this cooperative control is terminating larval diapause especially in the bamboo borer, Omphisa fuscidentalis.
Suphawan Suang, Manaporn Manaboon, Tippawan Singtripop, Kiyoshi Hiruma, Yu Kaneko, Pimonrat Tiansawat, Peter Neumann, Panuwan Chantawannakul   +7 more
doaj   +1 more source

Ecdysone Quantification from Whole Body Samples of Drosophila melanogaster Larvae

Bio-Protocol, 2021
Steroid hormones strictly control the timing of sexual maturation and final body size both in vertebrates and invertebrates. In insects, the steroid hormone ecdysone controls the timing of the molts between larval instars as well as the transition to ...
Takashi Koyama, Christen Mirth
doaj   +1 more source

Nuclear receptor DHR4 controls the timing of steroid hormone pulses during Drosophila development. [PDF]

PLoS Biology, 2011
In insects, precisely timed periodic pulses of the molting hormone ecdysone control major developmental transitions such as molts and metamorphosis. The synthesis and release of ecdysone, a steroid hormone, is itself controlled by PTTH (prothoracicotopic
Qiuxiang Ou, Adam Magico, Kirst King-Jones   +2 more
doaj   +1 more source

Network pharmacology combined with molecular docking to explore the anti-osteoporosis mechanisms of β-ecdysone derived from medicinal plants

Open Chemistry, 2022
β-Ecdysone is a phytosteroid derived from multifarious medicinal plants, such as Achyranthes root (Achyranthes bidentata) and Tinospora cordifolia, possessing the potential anti-osteoporosis effect.
Zeng Bin, Wu Xudong, Liang Wenqing, Huang Xiaogang   +3 more
doaj   +1 more source

Identification of Ecdysone Hormone Receptor Agonists as a Therapeutic Approach for Treating Filarial Infections. [PDF]

PLoS Neglected Tropical Diseases, 2016
BACKGROUND:A homologue of the ecdysone receptor has previously been identified in human filarial parasites. As the ecdysone receptor is not found in vertebrates, it and the regulatory pathways it controls represent attractive potential chemotherapeutic ...
Amruta S Mhashilkar, Sai L Vankayala, Canhui Liu, Fiona Kearns, Priyanka Mehrotra, George Tzertzinis, Subba R Palli, H Lee Woodcock, Thomas R Unnasch   +8 more
doaj   +1 more source

Ecdysone acts through cortex glia to regulate sleep in Drosophila

eLife, 2023
Steroid hormones are attractive candidates for transmitting long-range signals to affect behavior. These lipid-soluble molecules derived from dietary cholesterol easily penetrate the brain and act through nuclear hormone receptors (NHRs) that function as
Yongjun Li, Paula Haynes, Shirley L Zhang, Zhifeng Yue, Amita Sehgal   +4 more
doaj   +1 more source

Co-option of immune effectors by the hormonal signalling system triggering metamorphosis in Drosophila melanogaster.

PLoS Genetics, 2021
Insect metamorphosis is triggered by the production, secretion and degradation of 20-hydroxyecdysone (ecdysone). In addition to its role in developmental regulation, increasing evidence suggests that ecdysone is involved in innate immunity processes ...
Catarina Nunes, Takashi Koyama, Élio Sucena   +2 more
doaj   +1 more source

Cyromazine Effects the Reproduction of Drosophila by Decreasing the Number of Germ Cells in the Female Adult Ovary

Insects, 2022
In the present study, we observed a 58% decrease in the fecundity of Drosophila melanogaster, after treatment with the cyromazine. To further elucidate the effects of cyromazine on reproduction, we counted the number of both germline stem cells (GSCs ...
Muhammad Zaryab Khalid, Zhipeng Sun, Yaoyao Chen, Jing Zhang, Guohua Zhong   +4 more
doaj   +1 more source