Results 11 to 20 of about 14,789 (259)
A Genetic Mosaic Screen Reveals Ecdysone-Responsive Genes Regulating Drosophila Oogenesis
G3: Genes, Genomes, Genetics, 2016 Multiple aspects of Drosophila oogenesis, including germline stem cell activity, germ cell differentiation, and follicle survival, are regulated by the steroid hormone ecdysone.
Elizabeth T. Ables +4 more
doaj +2 more sources
Identification of Ecdysone Hormone Receptor Agonists as a Therapeutic Approach for Treating Filarial Infections. [PDF]
PLoS Neglected Tropical Diseases, 2016 BACKGROUND:A homologue of the ecdysone receptor has previously been identified in human filarial parasites. As the ecdysone receptor is not found in vertebrates, it and the regulatory pathways it controls represent attractive potential chemotherapeutic ...
Amruta S Mhashilkar +8 more
doaj +2 more sources
BMC Biology, 2018 Background Drosophila is a powerful model for the study of factors modulating innate immunity. This study examines the effect of water-loss dehydration on innate immune responsiveness in the Drosophila renal system (Malpighian tubules; MTs), and how this
Wenjing Zheng +6 more
doaj +2 more sources
Ecdysone signaling induces two phases of cell cycle exit in Drosophila cells
Biology Open, 2016 During development, cell proliferation and differentiation must be tightly coordinated to ensure proper tissue morphogenesis. Because steroid hormones are central regulators of developmental timing, understanding the links between steroid hormone ...
Yongfeng Guo +4 more
doaj +2 more sources
Polished Rice Regulates Maturation but Not Survival of Secondary Cells in Drosophila Male Accessory Gland. [PDF]
Genes CellsNutrient signal‐dependent expression of Dve and Ecdysone receptor (EcR) determines the optimal number of SCs during the critical period. Subsequent maturation is regulated by the small peptide Polished rice (Pri) through the nutrient signal‐dependent EcR‐FtzF1‐Pri‐AbdB pathway. ABSTRACT In Drosophila males, the accessory gland is responsive to nutrient
Otsune S +4 more
europepmc +2 more sources
Ecdysone acts through cortex glia to regulate sleep in Drosophila
bioRxiv, 2022 Steroid hormones are attractive candidates for transmitting long-range signals to affect behavior. These lipid-soluble molecules derived from dietary cholesterol easily penetrate the brain and act through nuclear hormone receptors (NHRs) that function as
Yongjun Li +4 more
semanticscholar +1 more source
Steroid hormone ecdysone deficiency stimulates preparation for photoperiodic reproductive diapause
PLoS Genetics, 2021 Diapause, a programmed developmental arrest primarily induced by seasonal environmental changes, is very common in the animal kingdom, and found in vertebrates and invertebrates alike.
Shuang Guo +6 more
semanticscholar +1 more source
Regulation of ecdysone production in Drosophila by neuropeptides and peptide hormones
Open Biology, 2021 In both mammals and insects, steroid hormones play a major role in directing the animal's progression through developmental stages. To maximize fitness outcomes, steroid hormone production is regulated by the environmental conditions experienced by the ...
J. Kannangara, C. Mirth, C. Warr
semanticscholar +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2021 Significance PRC2-mediated H3K27 methylation functions in epigenetic transcriptional repression and is involved in various developmental processes in eukaryotes.
Yan Yang +9 more
semanticscholar +1 more source
Ecdysone regulates Drosophila wing disc size via a TORC1 dependent mechanism
Nature Communications, 2021 Most cells in a developing organ stop proliferating when the organ reaches a correct, final size. The underlying molecular mechanisms are not understood. We find that in Drosophila the hormone ecdysone controls wing disc size.
K. Strassburger +3 more
semanticscholar +1 more source