Results 61 to 70 of about 23,261 (287)

Navigating the New Reality: A Review of the Epidemiological, Clinical, and Microbiological Characteristics of Candida auris, with a Focus on Children

Journal of Fungi, 2023
During the past decade, Candida auris emerged across the world, causing nosocomial outbreaks in both pediatric and adult populations, particularly in intensive care settings.
Liat Ashkenazi-Hoffnung, Chen Rosenberg Danziger   +1 more
doaj   +1 more source

The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation [PDF]

, 2017
We thank Cowen lab members for helpful discussions. We also thank David Rogers (University of Tennessee) for sharing microarray analysis of the CAS5 homozygous mutant, and Li Ang (University of Macau) for assistance in optimizing the ChIP-Seq experiments.
Andrews, Brenda J, Boone, Charles, Cowen, Leah E, Diaz, Jacinto De La Cruz, Grys, Ben T, Ho Wong, Koon, Ketela, Troy, Krieger, Jonathan R, Krysan, Damian J, Leach, Michelle D, Miao, Zhengqiang, Moran, Michael F, Qin, Longguang, Robbins, Nicole, Selmecki, Anna, Tan, Kaeling, Ting, Kenneth, Tong, Jiefei, Xie, Jinglin L   +18 more
core   +2 more sources

Emerging echinocandin-resistant Candida albicans and glabrata in Switzerland

Infection, 2020
Echinocandins represent the first-line therapy of candidemia. Echinocandin resistance among Candida spp. is mainly due to acquired FKS mutations. In this study, we report the emergence of FKS-mutant Candida albicans/glabrata in Switzerland and provide ...
A. Coste, A. Kritikos, J. Li, N. Khanna, D. Goldenberger, C. Garzoni, C. Zehnder, K. Boggian, D. Neofytos, A. Riat, D. Bachmann, D. Sanglard, F. Lamoth, F. N. K. D. Lamoth Khanna Boggian Sanglard, F. Lamoth, N. Khanna, K. Boggian, D. Sanglard   +17 more
semanticscholar   +1 more source

Treatment of Aspergillosis. [PDF]

, 2018
Infections caused by Aspergillus spp. remain associated with high morbidity and mortality. While mold-active antifungal prophylaxis has led to a decrease of occurrence of invasive aspergillosis (IA) in those patients most at risk for infection ...
Hoenigl, Martin, Jenks, Jeffrey D
core   +1 more source

Translation inhibition by rocaglates activates a species-specific cell death program in the emerging fungal pathogen Candida auris [PDF]

, 2020
Fungal infections are a major contributor to infectious disease-related deaths worldwide. Recently, global emergence of the fungal pathogen Candida auris has caused considerable concern because most C.
Brown, Lauren E., Cowen, Leah E., Henkel, Thomas, Iyer, Kali R., Porco, Jr., John A., Robbins, Nicole, Whitesell, Luke   +6 more
core   +1 more source

Gel Formulations with an Echinocandin for Cutaneous Candidiasis: The Influence of Azone and Transcutol on Biopharmaceutical Features

Gels, 2023
Caspofungin is a drug that is used for fungal infections that are difficult to treat, including invasive aspergillosis and candidemia, as well as other forms of invasive candidiasis.
Noelia Pérez-González, Lupe Carolina Espinoza, María Rincón, Lilian Sosa, Mireia Mallandrich, Joaquim Suñer-Carbó, Nuria Bozal-de Febrer, Ana Cristina Calpena, Beatriz Clares-Naveros   +8 more
doaj   +1 more source

Candida auris, what do paediatricians need to know? [PDF]

, 2018
AW is supported by the Wellcome Trust Strategic Award (grant 097377) and the MRC Centre for Medical Mycology (grant MR/N006364/1) at the University of Aberdeen.Peer reviewedPublisher ...
Warris, Adilia
core   +1 more source

Echinocandins in antifungal pharmacotherapy [PDF]

Journal of Pharmacy and Pharmacology, 2017
Abstract Objectives Echinocandins are the newest addition of the last decade to the antifungal armamentarium, which, owing to their unique mechanism of action, selectively target the fungal cells without affecting mammalian cells.
Akash Patil, Soumyajit Majumdar
openaire   +2 more sources

Treatment of Invasive Candidiasis: A Narrative Review

Journal of Fungi, 2018
Invasive candidiasis occurs frequently in hospitalized patients, and is associated with high mortality rates due to delays in recognition and initiation of appropriate antifungals.
Ronen Ben-Ami
doaj   +1 more source

A Hadal Streptomyces-Derived Echinocandin Acylase Discovered through the Prioritization of Protein Families

Marine Drugs
Naturally occurring echinocandin B and FR901379 are potent antifungal lipopeptides featuring a cyclic hexapeptide nucleus and a fatty acid side chain.
Xuejian Jiang, Hongjun Shu, Shuting Feng, Pinmei Wang, Zhizhen Zhang, Nan Wang   +5 more
doaj   +1 more source