Results 61 to 70 of about 17,768 (255)
The seizure of illicit assets: patterns of civil forfeiture in Canada and Ireland [PDF]
, 2013 No description ...
Gallant, M Michelle, King, Colin
core +1 more source
Repositioning Antimicrobial Peptides Against WHO‐Priority Fungi
Advanced Science, Volume 12, Issue 37, October 6, 2025.The growing burden of drug‐resistant fungal infections, driven by pathogens such as Candida auris, Cryptococcus neoformans, and Aspergillus fumigatus, underscores the urgent need for novel antifungal therapies. This review explores antimicrobial peptides as promising agents with membrane‐disruptive activity, immunomodulatory properties, and delivery ...
Cesar Augusto Roque‐Borda +12 more
wiley +1 more source
Archiv der Pharmazie, Volume 358, Issue 10, October 2025.A series of 13 hybrid molecules of both lead structures were prepared using reductive amination as key reaction step. The antimycotic potency of the resulting compounds was evaluated against yeast and mold species. Two compounds showed remarkable potency against several yeasts, and even against Candida krusei.
Marie‐Christin Hain +4 more
wiley +1 more source
Frontiers in Microbiology, 2019 A series of 4-(arylmethylene)-3-isochromanones have been prepared with base-catalyzed Knoevenagel condensation starting from 3-isochromanone and aromatic aldehydes.
Rodrigo Berzaghi +6 more
doaj +1 more source
Clumping Morphology Influences Virulence Uncoupled from Echinocandin Resistance in Candida glabrata
Microbiology Spectrum, 2022 Here, we report two paired sets of an index wild-type Candida glabrata bloodstream isolate and subsequent echinocandin-resistant FKS mutant. One paired set exhibited a higher proportion of clumping cells and was more virulent in the invertebrate host ...
Chenlin Hu +4 more
doaj +1 more source
Treatment of invasive candidiasis with echinocandins [PDF]
Mycoses, 2009 SummaryBlood stream infections by Candida spp. represent the majority of invasive fungal infections in intensive care patients. The high crude mortality of invasive candidiasis remained essentially unchanged during the last two decades despite new treatment options that became available.
Angela Steinbach +3 more
openaire +3 more sources
ChemistryOpen, Volume 14, Issue 10, October 2025.A series of azomethine‐pyrazole derivatives bearing a para‐substituted azo‐phenyl ring is straightforwardly prepared. The new compounds display an elevated antifungal activity against various Candida species and Cryptococcus neoformans strains. DFT and molecular docking calculations are used to determine possible routes of action through interactions ...
María Isabel Murillo +8 more
wiley +1 more source
Treatment of Invasive Candidiasis: A Narrative Review
Journal of Fungi, 2018 Invasive candidiasis occurs frequently in hospitalized patients, and is associated with high mortality rates due to delays in recognition and initiation of appropriate antifungals.
Ronen Ben-Ami
doaj +1 more source
ChemistryEurope, Volume 3, Issue 5, September 18, 2025.A standalone enzyme, derived from the reductase domain of a polyketide synthase‐nonribosomal peptide synthetase hybrid enzyme, is identified as a pyrroline carboxylate reductase. This enzyme is involved in the biosynthesis of 3‐methylproline, an amino acid building block of a unique tricyclic pyrrolizidinone structure of a fungal metabolite ...
Naoki Kato +6 more
wiley +1 more source
Fungal Resistance to Echinocandins and the MDR Phenomenon in Candida glabrata
Journal of Fungi, 2018 Candida glabrata has thoroughly adapted to successfully colonize human mucosal membranes and survive in vivo pressures. prior to and during antifungal treatment. Out of all the medically relevant Candida species, C.
Kelley R. Healey, David S. Perlin
doaj +1 more source