Results 121 to 130 of about 21,836 (300)

Clinical and Laboratory Development of Echinocandin Resistance in Candida glabrata: Molecular Characterization

Frontiers in Microbiology, 2019
The pathogenic yeast Candida glabrata has become a public health issue due to the increasing number of echinocandin resistant clinical strains reported.
Olga Rivero-Menendez, Patricia Navarro-Rodriguez, Leticia Bernal-Martinez, Leticia Bernal-Martinez, Gema Martin-Cano, Laura Lopez-Perez, Isabel Sanchez-Romero, Ana Perez-Ayala, Javier Capilla, Oscar Zaragoza, Oscar Zaragoza, Ana Alastruey-Izquierdo, Ana Alastruey-Izquierdo   +12 more
doaj   +1 more source

Extracellular Vesicles From Fungal Infection in Humans: A Key Player in Immunological Responses

Journal of Extracellular Biology, Volume 4, Issue 8, August 2025.
ABSTRACT Fungal infections cause approximately 1.6 million deaths annually. Diagnosing and treating fungal infections is difficult due to limited access to diagnostic tests and rising antifungal resistance. Extracellular vesicles (EVs) facilitate interactions between fungal cells and hosts, significantly influencing the pathogen‐host relationship ...
Caroline P. de Rezende, Patrick W. S. Santos, Renan A. Piraine, Virgínia C. Silvestrini, Julio C. J. Barbosa, Fabiana C. P. Valera, Edwin Tamashiro, Guilherme G. Podolski‐Gondim, Silvana M. Quintana, Rodrigo Calado, Roberto Martinez, Taicia P. Fill, Márcio L. Rodrigues, Fausto Almeida   +13 more
wiley   +1 more source

Candida glabrata : a review of its features and resistance [PDF]

, 2014
Candida species belong to the normal microbiota of the oral cavity and gastrointestinal and vaginal tracts, and are responsible for several clinical manifestations, from mucocutaneous overgrowth to bloodstream infections.
A Chakrabarti, A Chakrabarti, A Kalkanci, A Kramer, A Peñas De Las, A Roetzer, A Roetzer, A Roetzer, A Roetzer, A Thierry, AA Almeida de, AL Colombo, AM Calcagno, AM Nicola, AW Segal, B Dujon, B Guo, B Klempp-Selb, BB Magee, BD Alexander, BP Cormack, C Lass-Flörl, C Marcos-Arias, C. F. Rodrigues, CJ Seneviratne, CS Kaufmann, CS Lim, CT Hittinger, CY Lin, D Dyk van, D Wilson, DA Stead, DC Sheppard, DJ Klionsky, DJ Klionsky, DM Kuhn, DR Reagan, EA Kraneveld, EJ Helmerhorst, EJ Helmerhorst, EK Bethea, EM Kojic, F Bambeke Van, F Barchiesi, F Hasan, FC Odds, FG Oppenheim, FG Oppenheim, G Butler, G Butler, G Luo, G Luo, G Ramage, G Ramage, GM Cox, GR Thompson 3rd, H Muller, H Tsai, H Urk Van, H Wisplinghoff, HM Bandara, HT Taff, I Castaño, I Iraqui, J Chandra, J Chandra, J Kim, J Lee, JA Hagerty, JA Jayatilake, JA Noble, JA Vazquez, JA Vazquez, JCO Sardi, JE Bennett, JH Shin, JL Vincent, JP Vermitsky, JR Blankenship, K Gulshan, K Lewis, K Lewis, K Seider, K Ueno, KE Caudle, KH Chen, KH Wolfe, KJ Verstrepen, KW Henry, L Vale-Silva, LP Samaranayake, LP Samaranayake, M Bassetti, M Edgerton, M Negri, M Niimi, M Niimi, M Riera, M Sikora, M Tscherner, M. Henriques, MA Al-Fattani, MA Pfaller, MA Pfaller, MA Pfaller, MC Arendrup, MC Lorenz, MD LaFleur, MD Lafleur, MN Rai, N Berila, NK Tamura, O Bader, P Gutiérrez-Escribano, P Perumal, P Shahi, P Sundstrom, P Uppuluri, P Vandeputte, P Vandeputte, PL Fidel Jr, PW Groot De, R Domergue, R Kaur, R Kaur, R Kaur, R Rajendran, RA Akins, RA Calderone, RD Cannon, RK Shields, S Brunke, S Brunke, S Farahyar, S Ferrari, S Ferrari, S Hawser, S Paul, S Silva, S Silva, S Silva, S Silva, S Silva, S. Silva, SC Halliwell, SP Hawser, SY Ruan, T Miyazaki, T Saijo, TFC Mah, V Krcmery, V Krcmery, V Mohan das, Y Nakagawa, Z Jandric, Z Xie   +155 more
core   +1 more source

‘Case of the Month’ from Herlev and Gentofte Hospital, Denmark: candidaemia and fungus ball in a patient with diabetes on sodium‐glucose co‐transporter 2 inhibitor

BJU International, Volume 136, Issue 3, Page 408-411, September 2025.
Anne Sofie Frøkiær Mathiasen, Maria Feldborg Bruun Andersen, Valeria Antsupova, Mikkel Fode   +3 more
wiley   +1 more source

Invasive candidiasis as a cause of sepsis in the critically ill patient. [PDF]

, 2013
Invasive fungal infections are an increasingly frequent etiology of sepsis in critically ill patients causing substantial morbidity and mortality. Candida species are by far the predominant agent of fungal sepsis accounting for 10% to 15% of health-care ...
Calandra, T., Delaloye, J.
core   +1 more source

Susceptibility testing of Candida glabrata clinical strains to echinocandins using SensititreTM YeastOneTM system [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2018
Objective. To determine susceptibility of C. glabrata isolates to anidulafungin, caspofungin and micafungin using the SensititreTM YeastOneTM system. Materials and Methods. C. glabrata isolates were taken prospectively from clinical specimens or from
Veselov A.V., Vasilyeva N.V., Bogomolova T.S., Raush E.R., Kutsevalova O.Yu., Nizhegorodceva I.A., Petrova L.V., Shmidt N.V., Moskvitina E.N., Sukhorukova M.V., Ivanchik N.V., Kozlov R.S.   +11 more
doaj  

Structure-Activity Relationships of a Series of Echinocandins and the Discovery of CD101, a Highly Stable and Soluble Echinocandin with Distinctive Pharmacokinetic Properties

Antimicrobial Agents and Chemotherapy, 2016
Echinocandins are a first-line therapy for candidemia and invasive candidiasis. They are generally safe with few drug interactions, but the stability and pharmacokinetic properties of currently approved echinocandins are such that each was developed for ...
K. D. James, C. Laudeman, N. B. Malkar, R. Krishnan, K. Polowy   +4 more
semanticscholar   +1 more source

Antifungal Therapy: New Advances in the Understanding and Treatment of Mycosis [PDF]

, 2017
The high rates of morbidity and mortality caused by fungal infections are associated with the current limited antifungal arsenal and the high toxicity of the compounds.
Ana C. A. de Paula e Silva, Ana M. Fusco-Almeida, Caroline B. Costa-Orlandi, Caroline M. Marcos, Haroldo C. de Oliveira, Liliana Scorzoni, Maria J. S. Mendes-Giannini, Patrícia A. Assato, Wanessa C. M. A. de Melo   +8 more
core   +1 more source

Portrait of matrix gene expression in Candida glabrata biofilms with stress induced by different drugs [PDF]

, 2018
(1) Background: Candida glabrata is one of the most significant Candida species associated with severe cases of candidiasis. Biofilm formation is an important feature, closely associated with antifungal resistance, involving alterations of gene ...
Henriques, Mariana, Rodrigues, Célia F.
core   +2 more sources

SIGNIFICANCE OF YEASTS IN BLOODSTREAM INFECTION: EPIDEMIOLOGY AND PREDISPOSING FACTORS OF CANDIDAEMIA IN ADULT PATIENTS AT A UNIVERSITY HOSPITAL (2010-2014) [PDF]

, 2015
The incidence of Candida bloodstream infection (BSI) has increased during the past decades. Species distribution is changing worldwide, and non-albicans Candida spp. are becoming more prevalent.
Iván, Miklós, Juhász, Emese, Kristóf, Katalin, Pongrácz, Júlia   +3 more
core   +2 more sources